BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

843 related articles for article (PubMed ID: 30936558)

  • 1. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.
    Zhang P; Kishimoto Y; Grammatikakis I; Gottimukkala K; Cutler RG; Zhang S; Abdelmohsen K; Bohr VA; Misra Sen J; Gorospe M; Mattson MP
    Nat Neurosci; 2019 May; 22(5):719-728. PubMed ID: 30936558
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease.
    Vanzulli I; Papanikolaou M; De-La-Rocha IC; Pieropan F; Rivera AD; Gomez-Nicola D; Verkhratsky A; Rodríguez JJ; Butt AM
    Neurobiol Aging; 2020 Oct; 94():130-139. PubMed ID: 32619874
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease.
    Wei Z; Chen XC; Song Y; Pan XD; Dai XM; Zhang J; Cui XL; Wu XL; Zhu YG
    Chin Med J (Engl); 2016 Aug; 129(15):1835-44. PubMed ID: 27453234
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
    Sebastian Monasor L; Müller SA; Colombo AV; Tanrioever G; König J; Roth S; Liesz A; Berghofer A; Piechotta A; Prestel M; Saito T; Saido TC; Herms J; Willem M; Haass C; Lichtenthaler SF; Tahirovic S
    Elife; 2020 Jun; 9():. PubMed ID: 32510331
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
    Shin MK; Kim HG; Baek SH; Jung WR; Park DI; Park JS; Jo DG; Kim KL
    Neurobiol Aging; 2014 May; 35(5):990-1001. PubMed ID: 24268884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.
    Ricke KM; Cruz SA; Qin Z; Farrokhi K; Sharmin F; Zhang L; Zasloff MA; Stewart AFR; Chen HH
    J Neurosci; 2020 Feb; 40(7):1581-1593. PubMed ID: 31915254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Zhang W; Hao J; Liu R; Zhang Z; Lei G; Su C; Miao J; Li Z
    Behav Brain Res; 2011 Sep; 222(2):342-50. PubMed ID: 21513747
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.
    Zhang W; Zhang W; Li Z; Hao J; Zhang Z; Liu L; Mao N; Miao J; Zhang L
    Pharmacol Biochem Behav; 2012 Jan; 100(3):361-9. PubMed ID: 21993310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
    Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
    J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
    [No Abstract]   [Full Text] [Related]  

  • 10. Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
    Meilandt WJ; Cisse M; Ho K; Wu T; Esposito LA; Scearce-Levie K; Cheng IH; Yu GQ; Mucke L
    J Neurosci; 2009 Feb; 29(7):1977-86. PubMed ID: 19228952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
    Baik SH; Kang S; Son SM; Mook-Jung I
    Glia; 2016 Dec; 64(12):2274-2290. PubMed ID: 27658617
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.
    Zeng Y; Zhang J; Zhu Y; Zhang J; Shen H; Lu J; Pan X; Lin N; Dai X; Zhou M; Chen X
    J Neurochem; 2015 Apr; 133(1):38-52. PubMed ID: 25661995
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SEN1500, a novel oral amyloid-β aggregation inhibitor, attenuates brain pathology in a mouse model of Alzheimer's disease.
    Brunner D; Flunkert S; Neddens J; Duller S; Scopes DIC; Treherne JM; Hutter-Paier B
    Neurosci Lett; 2017 Nov; 660():96-102. PubMed ID: 28917978
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.
    Zhang XM; Cai Y; Xiong K; Cai H; Luo XG; Feng JC; Clough RW; Struble RG; Patrylo PR; Yan XX
    Eur J Neurosci; 2009 Dec; 30(12):2271-83. PubMed ID: 20092570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.
    Peng Y; Sun J; Hon S; Nylander AN; Xia W; Feng Y; Wang X; Lemere CA
    J Neurosci; 2010 Jun; 30(24):8180-9. PubMed ID: 20554868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease.
    Wu X; Kosaraju J; Zhou W; Tam KY
    ACS Chem Neurosci; 2017 Mar; 8(3):676-685. PubMed ID: 28032988
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model.
    Martínez-Mármol R; Mohannak N; Qian L; Wang T; Gormal RS; Ruitenberg MJ; Vanhaesebroeck B; Coulson EJ; Meunier FA
    J Neurosci; 2019 Oct; 39(40):7976-7991. PubMed ID: 31363064
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multifocal Cerebral Microinfarcts Modulate Early Alzheimer's Disease Pathology in a Sex-Dependent Manner.
    Lecordier S; Pons V; Rivest S; ElAli A
    Front Immunol; 2021; 12():813536. PubMed ID: 35173711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.
    Guo XD; Sun GL; Zhou TT; Xu X; Zhu ZY; Rukachaisirikul V; Hu LH; Shen X
    Acta Pharmacol Sin; 2016 Sep; 37(10):1281-1297. PubMed ID: 27569389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.
    Hoshino T; Murao N; Namba T; Takehara M; Adachi H; Katsuno M; Sobue G; Matsushima T; Suzuki T; Mizushima T
    J Neurosci; 2011 Apr; 31(14):5225-34. PubMed ID: 21471357
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.