344 related articles for article (PubMed ID: 30937520)
1. FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Marrone L; Drexler HCA; Wang J; Tripathi P; Distler T; Heisterkamp P; Anderson EN; Kour S; Moraiti A; Maharana S; Bhatnagar R; Belgard TG; Tripathy V; Kalmbach N; Hosseinzadeh Z; Crippa V; Abo-Rady M; Wegner F; Poletti A; Troost D; Aronica E; Busskamp V; Weis J; Pandey UB; Hyman AA; Alberti S; Goswami A; Sterneckert J
Acta Neuropathol; 2019 Jul; 138(1):67-84. PubMed ID: 30937520
[TBL] [Abstract][Full Text] [Related]
2. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
Harley J; Patani R
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
[TBL] [Abstract][Full Text] [Related]
3. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
[TBL] [Abstract][Full Text] [Related]
4. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
[TBL] [Abstract][Full Text] [Related]
5. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A
Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359
[TBL] [Abstract][Full Text] [Related]
6. Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy.
Castillo Bautista CM; Eismann K; Gentzel M; Pelucchi S; Mertens J; Walters HE; Yun MH; Sterneckert J
Cells; 2023 Sep; 12(18):. PubMed ID: 37759469
[TBL] [Abstract][Full Text] [Related]
7. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
8. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
[TBL] [Abstract][Full Text] [Related]
9. 4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.
Naujock M; Stanslowsky N; Bufler S; Naumann M; Reinhardt P; Sterneckert J; Kefalakes E; Kassebaum C; Bursch F; Lojewski X; Storch A; Frickenhaus M; Boeckers TM; Putz S; Demestre M; Liebau S; Klingenstein M; Ludolph AC; Dengler R; Kim KS; Hermann A; Wegner F; Petri S
Stem Cells; 2016 Jun; 34(6):1563-75. PubMed ID: 26946488
[TBL] [Abstract][Full Text] [Related]
10. Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
Farg MA; Soo KY; Warraich ST; Sundaramoorthy V; Blair IP; Atkin JD
Hum Mol Genet; 2013 Feb; 22(4):717-28. PubMed ID: 23172909
[TBL] [Abstract][Full Text] [Related]
11. Disrupted autophagy and neuronal dysfunction in C. elegans knockin models of FUS amyotrophic lateral sclerosis.
Baskoylu SN; Chapkis N; Unsal B; Lins J; Schuch K; Simon J; Hart AC
Cell Rep; 2022 Jan; 38(4):110195. PubMed ID: 35081350
[TBL] [Abstract][Full Text] [Related]
12. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
[TBL] [Abstract][Full Text] [Related]
13. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
[TBL] [Abstract][Full Text] [Related]
14. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L
Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725
[TBL] [Abstract][Full Text] [Related]
15. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
16. M
Di Timoteo G; Giuliani A; Setti A; Biagi MC; Lisi M; Santini T; Grandioso A; Mariani D; Castagnetti F; Perego E; Zappone S; Lattante S; Sabatelli M; Rotili D; Vicidomini G; Bozzoni I
Nat Commun; 2024 Jun; 15(1):5033. PubMed ID: 38866783
[TBL] [Abstract][Full Text] [Related]
17. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.
De Santis R; Alfano V; de Turris V; Colantoni A; Santini L; Garone MG; Antonacci G; Peruzzi G; Sudria-Lopez E; Wyler E; Anink JJ; Aronica E; Landthaler M; Pasterkamp RJ; Bozzoni I; Rosa A
Cell Rep; 2019 Jun; 27(13):3818-3831.e5. PubMed ID: 31242416
[TBL] [Abstract][Full Text] [Related]
18. [The FUS protein: Physiological functions and a role in amyotrophic lateral sclerosis].
Efimova AD; Ovchinnikov RK; Roman AY; Maltsev AV; Grigoriev VV; Kovrazhkina EA; Skvortsova VI
Mol Biol (Mosk); 2017; 51(3):387-399. PubMed ID: 28707655
[TBL] [Abstract][Full Text] [Related]
19. Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L; Poser I; Casci I; Japtok J; Reinhardt P; Janosch A; Andree C; Lee HO; Moebius C; Koerner E; Reinhardt L; Cicardi ME; Hackmann K; Klink B; Poletti A; Alberti S; Bickle M; Hermann A; Pandey UB; Hyman AA; Sterneckert JL
Stem Cell Reports; 2018 Feb; 10(2):375-389. PubMed ID: 29358088
[TBL] [Abstract][Full Text] [Related]
20. Cytoplasmic aggregation of mutant FUS causes multistep RNA splicing perturbations in the course of motor neuron pathology.
Rezvykh AP; Ustyugov AA; Chaprov KD; Teterina EV; Nebogatikov VO; Spasskaya DS; Evgen'ev MB; Morozov AV; Funikov SY
Nucleic Acids Res; 2023 Jun; 51(11):5810-5830. PubMed ID: 37115004
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
