BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 30937959)

  • 1. Bioprospection of anti-inflammatory phytochemicals suggests rutaecarpine and quinine as promising 15-lipoxygenase inhibitors.
    Gurung AB; Pamay P; Tripathy D; Biswas K; Chatterjee A; Joshi SR; Bhattacharjee A
    J Cell Biochem; 2019 Aug; 120(8):13598-13613. PubMed ID: 30937959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 'Mechanistic insights into 5-lipoxygenase inhibition by active principles derived from essential oils of Curcuma species: Molecular docking, ADMET analysis and molecular dynamic simulation study.
    Gadnayak A; Dehury B; Nayak A; Jena S; Sahoo A; Panda PC; Ray A; Nayak S
    PLoS One; 2022; 17(7):e0271956. PubMed ID: 35867724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lipoxygenase directed anti-inflammatory and anti-cancerous secondary metabolites: ADMET-based screening, molecular docking and dynamics simulation.
    Singh S; Awasthi M; Pandey VP; Dwivedi UN
    J Biomol Struct Dyn; 2017 Feb; 35(3):657-668. PubMed ID: 26942689
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity.
    Naaz F; Preeti Pallavi MC; Shafi S; Mulakayala N; Shahar Yar M; Sampath Kumar HM
    Bioorg Chem; 2018 Dec; 81():1-20. PubMed ID: 30081353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
    Omar YM; Abdu-Allah HHM; Abdel-Moty SG
    Bioorg Chem; 2018 Oct; 80():461-471. PubMed ID: 29986191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The bioactive alkaloids identified from Cortex Phellodendri ameliorate benign prostatic hyperplasia via LOX-5/COX-2 pathways.
    Wang S; Lee DY; Shang Y; Liao J; Cao X; Xie L; Zhang T; Liu J; Dai R
    Phytomedicine; 2021 Dec; 93():153813. PubMed ID: 34735909
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX.
    Bhuktar H; Shukla S; Kakularam KR; Battu S; Srikanth M; Srivastava S; Medishetti R; Ram P; Jagadish PC; Rasool M; Chakraborty S; Khan N; Reddanna P; Oruganti S; Pal M
    Bioorg Chem; 2023 Sep; 138():106606. PubMed ID: 37210826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF; Ali WAM; Bazgier V; Rárová L
    Eur J Med Chem; 2016 Nov; 123():803-813. PubMed ID: 27541263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
    Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-B-RUT, a derivative of RUT, protected against alcohol-induced liver injury by attenuating inflammation and oxidative stress.
    Xu JJ; Li HD; Wu MF; Zhu L; Du XS; Li JJ; Li Z; Meng XM; Huang C; Li J
    Int Immunopharmacol; 2021 Jun; 95():107471. PubMed ID: 33756231
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y; Zhang B; Li J; Liu H; Zhang Y; Yang Z; Liu W
    Eur J Med Chem; 2019 Oct; 180():41-50. PubMed ID: 31299586
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rutaecarpine ameliorated sepsis-induced peritoneal resident macrophages apoptosis and inflammation responses.
    Li Z; Yang M; Peng Y; Gao M; Yang B
    Life Sci; 2019 Jul; 228():11-20. PubMed ID: 30690081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: In vitro and in silico studies.
    Theoduloz C; Alzate-Morales J; Jiménez-Aspee F; Isla MI; Alberto MR; Pertino MW; Schmeda-Hirschmann G
    Chem Biol Drug Des; 2019 Mar; 93(3):290-299. PubMed ID: 30294891
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF; Philoppes JN; Rárová L
    Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700311. PubMed ID: 29400411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evodiamine and rutaecarpine from Tetradium ruticarpum in the treatment of liver diseases.
    Li X; Ge J; Zheng Q; Zhang J; Sun R; Liu R
    Phytomedicine; 2020 Mar; 68():153180. PubMed ID: 32092638
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study.
    Liu J; Guo H; Zhou J; Wang Y; Yan H; Jin R; Tang Y
    Int J Mol Sci; 2022 Sep; 23(19):. PubMed ID: 36232809
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I; Rizk OH; Ibrahim TM; Henen SS; El-Khawass EM; Bayad AE; El-Ashmawy IM; Nematalla HA
    Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Benzimidazole scaffold based hybrid molecules for various inflammatory targets: Synthesis and evaluation.
    Kaur G; Silakari O
    Bioorg Chem; 2018 Oct; 80():24-35. PubMed ID: 29864685
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phytochemicals as multi-target inhibitors of the inflammatory pathway- A modeling and experimental study.
    Devi NS; Ramanan M; Paragi-Vedanthi P; Doble M
    Biochem Biophys Res Commun; 2017 Mar; 484(3):467-473. PubMed ID: 28088519
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.