BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 30947315)

  • 1. Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability.
    Abdelhameed AS; Kadi AA; Attwa MW; AlRabiah H
    PLoS One; 2019; 14(4):e0214598. PubMed ID: 30947315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC-MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies.
    Attwa MW; Kadi AA; Abdelhameed AS; Alhazmi HA
    Drug Des Devel Ther; 2020; 14():783-793. PubMed ID: 32158196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simultaneous determination of dacomitinib and its major metabolite, O-desmethyl dacomitinib in human plasma by LC-MS/MS and its application to clinical testing in patients with non-small cell lung cancer.
    Feng X; Ding Y; Zhang P; Fu Q; Zhang L; Zheng H
    J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Oct; 1182():122940. PubMed ID: 34564058
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development and validation of an HPLC-MS/MS method for the determination of filgotinib, a selective Janus kinase 1 inhibitor: Application to a metabolic stability study.
    AlRabiah H; Kadi AA; Attwa MW; Mostafa GAE
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Oct; 1154():122195. PubMed ID: 32943176
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LC-MS/MS Estimation of Rociletinib Levels in Human Liver Microsomes: Application to Metabolic Stability Estimation.
    Attwa MW; Abdelhameed AS; Kadi AA
    Drug Des Devel Ther; 2021; 15():3915-3925. PubMed ID: 34552321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability.
    Kadi AA; Darwish HW; Attwa MW; Amer SM
    PLoS One; 2016; 11(10):e0164967. PubMed ID: 27764191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes.
    Mostafa GAE; Kadi AA; AlMasoud N; Attwa MW; Al-Shakliah NS; AlRabiah H
    J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Aug; 1179():122806. PubMed ID: 34325312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative bioanalytical assay for the human epidermal growth factor receptor (HER) inhibitor dacomitinib in rat plasma by UPLC-MS/MS.
    Qiu X; Lin Q; Ning Z; Qian X; Li P; Ye L; Xie S
    J Pharm Biomed Anal; 2019 Mar; 166():66-70. PubMed ID: 30612075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation.
    Attwa MW; AlRabiah H; Mostafa GAE; Kadi AA
    Molecules; 2023 Mar; 28(5):. PubMed ID: 36903565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method.
    Attwa MW; AlRabiah H; Mostafa GAE; Bakheit AH; Kadi AA
    Molecules; 2023 Mar; 28(6):. PubMed ID: 36985590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation.
    Amer SM; Kadi AA; Darwish HW; Attwa MW
    Chem Cent J; 2017 May; 11(1):45. PubMed ID: 29086823
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LC-MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate.
    Amer SM; Kadi AA; Darwish HW; Attwa MW
    Chem Cent J; 2017 Dec; 11(1):136. PubMed ID: 29274040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes.
    Attwa MW; AlRabiah H; Kadi AA
    Molecules; 2023 Mar; 28(5):. PubMed ID: 36903615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantification of the irreversible fibroblast growth factor receptor inhibitor futibatinib by UPLC-MS/MS: Application to the metabolic stability assay in human liver microsomes for the estimation of its in vitro hepatic intrinsic clearance.
    Tang LWT; Chan ECY
    J Pharm Biomed Anal; 2022 May; 214():114731. PubMed ID: 35325798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation.
    Abdelhameed AS; Attwa MW; Al-Shaklia NS; Kadi AA
    R Soc Open Sci; 2019 Jun; 6(6):190434. PubMed ID: 31312501
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessment.
    Alrabiah H; Kadi AA; Attwa MW; Abdelhameed AS
    RSC Adv; 2019 Feb; 9(9):4862-4869. PubMed ID: 35514667
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry.
    Attwa MW; Kadi AA; Darwish HW
    Drug Des Devel Ther; 2020; 14():111-119. PubMed ID: 32021096
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and validation of a new liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of afatinib, dacomitinib, osimertinib, and the active metabolites of osimertinib in human serum.
    Ishikawa E; Yokoyama Y; Chishima H; Kuniyoshi O; Sato I; Nakaya N; Nakajima H; Kimura M; Hakamata J; Suehiro N; Nakada H; Ikemura S; Jibiki A; Kawazoe H; Muramatsu H; Suzuki S; Nakamura T
    J Chromatogr B Analyt Technol Biomed Life Sci; 2022 May; 1199():123245. PubMed ID: 35436724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: Application to metabolic stability investigation and excretion rate.
    Attwa MW; Kadi AA; Darwish HW; Amer SM; Alrabiah H
    Eur J Mass Spectrom (Chichester); 2018 Aug; 24(4):344-351. PubMed ID: 29629565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay.
    Attwa MW; Abdelhameed AS; Al-Shakliah NS; Kadi AA
    Drug Des Devel Ther; 2020; 14():4439-4449. PubMed ID: 33122888
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.