BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 30947659)

  • 21. MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells.
    Mulherkar N; Prasad KV; Prabhakar BS
    J Biol Chem; 2007 Apr; 282(16):11715-21. PubMed ID: 17314102
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4.
    Li P; Jayarama S; Ganesh L; Mordi D; Carr R; Kanteti P; Hay N; Prabhakar BS
    J Biol Chem; 2010 Jul; 285(29):22713-22. PubMed ID: 20484047
    [TBL] [Abstract][Full Text] [Related]  

  • 23. DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease.
    Mo Y; Williams C; Miller CA
    J Mol Neurosci; 2012 Sep; 48(1):97-110. PubMed ID: 22678883
    [TBL] [Abstract][Full Text] [Related]  

  • 24. IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs.
    Efimova EV; Al-Zoubi AM; Martinez O; Kaithamana S; Lu S; Arima T; Prabhakar BS
    Oncogene; 2004 Feb; 23(5):1076-87. PubMed ID: 14716293
    [TBL] [Abstract][Full Text] [Related]  

  • 25. miR-181 interacts with signaling adaptor molecule DENN/MADD and enhances TNF-induced cell death.
    Ghorbani S; Talebi F; Ghasemi S; Jahanbazi Jahan Abad A; Vojgani M; Noorbakhsh F
    PLoS One; 2017; 12(3):e0174368. PubMed ID: 28323882
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D.
    Zhang T; Hu Y; Ju J; Hou L; Li Z; Xiao D; Li Y; Yao J; Wang C; Zhang Y; Zhang L
    Sci Rep; 2016 Jan; 6():19346. PubMed ID: 26783084
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons.
    Del Villar K; Miller CA
    Proc Natl Acad Sci U S A; 2004 Mar; 101(12):4210-5. PubMed ID: 15007167
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [Sequence-dependent effect of docetaxel with gefitinib on the proliferation and signal protein expression of human lung adenocarcinoma cell SPC-A1].
    Zhang W; Zhang W; Wang L; Zheng J; Xiao F
    Zhongguo Fei Ai Za Zhi; 2011 May; 14(5):385-90. PubMed ID: 21569641
    [TBL] [Abstract][Full Text] [Related]  

  • 29. IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth.
    Efimova E; Martinez O; Lokshin A; Arima T; Prabhakar BS
    Cancer Res; 2003 Dec; 63(24):8768-76. PubMed ID: 14695193
    [TBL] [Abstract][Full Text] [Related]  

  • 30. [Inhibition Function of Dominant-negative Mutant Gene Survivin-D53A to SPC-A1 Lung Adenocarcinoma Xenograft in Nude Mice Models].
    Yu M; Peng X; Lu Y; Huang M
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2015 Jun; 32(3):624-8. PubMed ID: 26485989
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Induction of marked apoptosis in mammalian cancer cell lines by antisense DNA treatment to abolish expression of DENN (differentially expressed in normal and neoplastic cells).
    Lim KM; Chow VT
    Mol Carcinog; 2002 Nov; 35(3):110-26. PubMed ID: 12410563
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of livin expression suppresses cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma cells.
    Zhuang L; Shen LD; Li K; Yang RX; Zhang QY; Chen Y; Gao CL; Dong C; Bi Q; Tao JN; Wang XN; Tian Q
    Mol Med Rep; 2015 Jul; 12(1):547-52. PubMed ID: 25695324
    [TBL] [Abstract][Full Text] [Related]  

  • 33. siRNA-induced TRAF6 knockdown promotes the apoptosis and inhibits the invasion of human lung cancer SPC-A1 cells.
    He Z; Huang C; Lin G; Ye Y
    Oncol Rep; 2016 Apr; 35(4):1933-40. PubMed ID: 26847475
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene.
    Li LC; Sheng JR; Mulherkar N; Prabhakar BS; Meriggioli MN
    Cancer Res; 2008 Sep; 68(18):7352-61. PubMed ID: 18794122
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells.
    Li LC; Jayaram S; Ganesh L; Qian L; Rotmensch J; Maker AV; Prabhakar BS
    Am J Obstet Gynecol; 2011 Oct; 205(4):362.e12-25. PubMed ID: 21855847
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder.
    Schneeberger PE; Kortüm F; Korenke GC; Alawi M; Santer R; Woidy M; Buhas D; Fox S; Juusola J; Alfadhel M; Webb BD; Coci EG; Abou Jamra R; Siekmeyer M; Biskup S; Heller C; Maier EM; Javaher-Haghighi P; Bedeschi MF; Ajmone PF; Iascone M; Peeters H; Ballon K; Jaeken J; Rodríguez Alonso A; Palomares-Bralo M; Santos-Simarro F; Meuwissen MEC; Beysen D; Kooy RF; Houlden H; Murphy D; Doosti M; Karimiani EG; Mojarrad M; Maroofian R; Noskova L; Kmoch S; Honzik T; Cope H; Sanchez-Valle A; ; Gelb BD; Kurth I; Hempel M; Kutsche K
    Brain; 2020 Aug; 143(8):2437-2453. PubMed ID: 32761064
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo.
    Xu C; Gui Q; Chen W; Wu L; Sun W; Zhang N; Xu Q; Wang J; Fu X
    J Exp Clin Cancer Res; 2011 May; 30(1):63. PubMed ID: 21619686
    [TBL] [Abstract][Full Text] [Related]  

  • 38. IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.
    Ramaswamy M; Efimova EV; Martinez O; Mulherkar NU; Singh SP; Prabhakar BS
    Oncogene; 2004 Aug; 23(36):6083-94. PubMed ID: 15208670
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Aurora-A/NF-ĸB Signaling Is Associated With Radio-resistance in Human Lung Adenocarcinoma.
    Liu JB; Hu L; Yang Z; Sun YU; Hoffman RM; Yi Z
    Anticancer Res; 2019 Nov; 39(11):5991-5998. PubMed ID: 31704824
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Homozygous variant in MADD, encoding a Rab guanine nucleotide exchange factor, results in pleiotropic effects and a multisystemic disorder.
    Abu-Libdeh B; Mor-Shaked H; Atawna AA; Gillis D; Halstuk O; Shaul-Lotan N; Slae M; Sultan M; Meiner V; Elpeleg O; Harel T
    Eur J Hum Genet; 2021 Jun; 29(6):977-987. PubMed ID: 33723354
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.