140 related articles for article (PubMed ID: 30948782)
1. Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells.
Allende-Vega N; Villalba M
Sci Rep; 2019 Apr; 9(1):5637. PubMed ID: 30948782
[TBL] [Abstract][Full Text] [Related]
2. The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism.
Allende-Vega N; Krzywinska E; Orecchioni S; Lopez-Royuela N; Reggiani F; Talarico G; Rossi JF; Rossignol R; Hicheri Y; Cartron G; Bertolini F; Villalba M
Oncotarget; 2015 Aug; 6(22):19228-45. PubMed ID: 26231043
[TBL] [Abstract][Full Text] [Related]
3. Dominant-negative p53 mutant R248Q increases the motile and invasive activities of oral squamous cell carcinoma cells.
Nakazawa S; Sakata KI; Liang S; Yoshikawa K; Iizasa H; Tada M; Hamada JI; Kashiwazaki H; Kitagawa Y; Yamazaki Y
Biomed Res; 2019; 40(1):37-49. PubMed ID: 30787262
[TBL] [Abstract][Full Text] [Related]
4. Chaperone-mediated autophagy degrades mutant p53.
Vakifahmetoglu-Norberg H; Kim M; Xia HG; Iwanicki MP; Ofengeim D; Coloff JL; Pan L; Ince TA; Kroemer G; Brugge JS; Yuan J
Genes Dev; 2013 Aug; 27(15):1718-30. PubMed ID: 23913924
[TBL] [Abstract][Full Text] [Related]
5. Mutant p53
Hernández-Reséndiz I; Gallardo-Pérez JC; López-Macay A; Robledo-Cadena DX; García-Villa E; Gariglio P; Saavedra E; Moreno-Sánchez R; Rodríguez-Enríquez S
J Cell Physiol; 2019 May; 234(5):5524-5536. PubMed ID: 30272821
[TBL] [Abstract][Full Text] [Related]
6. Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG.
Liu H; Zhang T; Chen R; McConkey DJ; Ward JF; Curley SA
J Surg Res; 2012 Jul; 176(1):147-53. PubMed ID: 22099584
[TBL] [Abstract][Full Text] [Related]
7. P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines.
Shintani S; Zhang T; Aslam A; Sebastian K; Yoshimura T; Hamakawa H
Int J Oncol; 2006 Nov; 29(5):1111-7. PubMed ID: 17016641
[TBL] [Abstract][Full Text] [Related]
8. Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting Mdm2-mediated p53-R248Q ubiquitination and degradation.
Wu AY; Gu LY; Cang W; Cheng MX; Wang WJ; Di W; Huang L; Qiu LH
J Exp Clin Cancer Res; 2019 Apr; 38(1):176. PubMed ID: 31023317
[TBL] [Abstract][Full Text] [Related]
9. R248Q mutation--Beyond p53-DNA binding.
Ng JW; Lama D; Lukman S; Lane DP; Verma CS; Sim AY
Proteins; 2015 Dec; 83(12):2240-50. PubMed ID: 26442703
[TBL] [Abstract][Full Text] [Related]
10. A degradative detour for mutant TP53.
Vakifahmetoglu-Norberg H; Yuan J
Autophagy; 2013 Dec; 9(12):2158-60. PubMed ID: 24145670
[TBL] [Abstract][Full Text] [Related]
11. Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
Al Shaer L; Walsby E; Gilkes A; Tonks A; Walsh V; Mills K; Burnett A; Rowntree C
Br J Haematol; 2008 May; 141(4):483-93. PubMed ID: 18373709
[TBL] [Abstract][Full Text] [Related]
12. Ganetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent manner.
Alexandrova EM; Xu S; Moll UM
Cell Death Dis; 2017 Mar; 8(3):e2683. PubMed ID: 28300840
[TBL] [Abstract][Full Text] [Related]
13. Elucidating the Mechanisms of R248Q Mutation-Enhanced p53 Aggregation and Its Inhibition by Resveratrol.
Liu Q; Li L; Yu Y; Wei G
J Phys Chem B; 2023 Sep; 127(36):7708-7720. PubMed ID: 37665658
[TBL] [Abstract][Full Text] [Related]
14. Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights.
Merabet A; Houlleberghs H; Maclagan K; Akanho E; Bui TT; Pagano B; Drake AF; Fraternali F; Nikolova PV
Biochem J; 2010 Mar; 427(2):225-36. PubMed ID: 20113312
[TBL] [Abstract][Full Text] [Related]
15. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level.
Yu W; Rao Q; Wang M; Tian Z; Lin D; Liu X; Wang J
Leuk Res; 2006 May; 30(5):575-82. PubMed ID: 16213582
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of autophagy with chloroquine is effective in melanoma.
Egger ME; Huang JS; Yin W; McMasters KM; McNally LR
J Surg Res; 2013 Sep; 184(1):274-81. PubMed ID: 23706562
[TBL] [Abstract][Full Text] [Related]
17. Synergism between etoposide and 17-AAG in leukemia cells: critical roles for Hsp90, FLT3, topoisomerase II, Chk1, and Rad51.
Yao Q; Weigel B; Kersey J
Clin Cancer Res; 2007 Mar; 13(5):1591-600. PubMed ID: 17332306
[TBL] [Abstract][Full Text] [Related]
18. Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells.
Yoshikawa K; Hamada J; Tada M; Kameyama T; Nakagawa K; Suzuki Y; Ikawa M; Hassan NM; Kitagawa Y; Moriuchi T
Biomed Res; 2010 Dec; 31(6):401-11. PubMed ID: 21187651
[TBL] [Abstract][Full Text] [Related]
19. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ.
Wang H; Bao W; Jiang F; Che Q; Chen Z; Wang F; Tong H; Dai C; He X; Liao Y; Liu B; Sun J; Wan X
Cancer Lett; 2015 May; 360(2):269-79. PubMed ID: 25697482
[TBL] [Abstract][Full Text] [Related]
20. Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
Robles AI; Wright MH; Gandhi B; Feis SS; Hanigan CL; Wiestner A; Varticovski L
Clin Cancer Res; 2006 Nov; 12(21):6547-56. PubMed ID: 17085670
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]