BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 30949773)

  • 21. Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules.
    Cho JH; Johnson GV
    J Neurochem; 2004 Jan; 88(2):349-58. PubMed ID: 14690523
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer.
    Ahuja LG; Kornev AP; McClendon CL; Veglia G; Taylor SS
    Proc Natl Acad Sci U S A; 2017 Feb; 114(6):E931-E940. PubMed ID: 28115705
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The binding and phosphorylation of Thr231 is critical for Tau's hyperphosphorylation and functional regulation by glycogen synthase kinase 3beta.
    Lin YT; Cheng JT; Liang LC; Ko CY; Lo YK; Lu PJ
    J Neurochem; 2007 Oct; 103(2):802-13. PubMed ID: 17680984
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of two potential glycogen synthase kinase 3β inhibitors for the treatment of osteosarcoma.
    Lu K; Wang X; Chen Y; Liang D; Luo H; Long L; Hu Z; Bao J
    Acta Biochim Biophys Sin (Shanghai); 2018 May; 50(5):456-464. PubMed ID: 29546355
    [TBL] [Abstract][Full Text] [Related]  

  • 25. How do mutations and allosteric inhibitors modulate caspase-7 activity? A molecular dynamics study.
    Bingöl EN; Serçinoğlu O; Ozbek P
    J Biomol Struct Dyn; 2019 Aug; 37(13):3456-3466. PubMed ID: 30175666
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Intrinsic Dynamics of the Binding Rail and Its Allosteric Effect in the Class I Histone Deacetylases.
    Zhou J; Huang Y; Cheng C; Wang K; Wu R
    J Chem Inf Model; 2017 Sep; 57(9):2309-2320. PubMed ID: 28805377
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs.
    Balasubramaniam M; Mainali N; Bowroju SK; Atluri P; Penthala NR; Ayyadevera S; Crooks PA; Shmookler Reis RJ
    Sci Rep; 2020 Oct; 10(1):18326. PubMed ID: 33110096
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Xanthone glucoside 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one binds to the ATP-binding pocket of glycogen synthase kinase 3β and inhibits its activity: implications in prostate cancer and associated cardiovascular disease risk.
    Mangangcha IR; Brojen Singh RK; Lebeche D; Ali S
    J Biomol Struct Dyn; 2022 Oct; 40(17):7868-7884. PubMed ID: 33769184
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.
    Dajani R; Fraser E; Roe SM; Yeo M; Good VM; Thompson V; Dale TC; Pearl LH
    EMBO J; 2003 Feb; 22(3):494-501. PubMed ID: 12554650
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MD simulations indicate Omicron P132H of SARS-CoV-2 M
    Bhat ZA; Khan MM; Rehman A; Iqbal J; Sanjeev BS; Madhumalar A
    Int J Biol Macromol; 2024 Mar; 262(Pt 2):130077. PubMed ID: 38346625
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.
    James KA; Verkhivker GM
    PLoS One; 2014; 9(11):e113488. PubMed ID: 25427151
    [TBL] [Abstract][Full Text] [Related]  

  • 32. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
    Keedy DA; Hill ZB; Biel JT; Kang E; Rettenmaier TJ; Brandão-Neto J; Pearce NM; von Delft F; Wells JA; Fraser JS
    Elife; 2018 Jun; 7():. PubMed ID: 29877794
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport.
    Banerjee R; Rudloff Z; Naylor C; Yu MC; Gunawardena S
    Hum Mol Genet; 2018 Sep; 27(17):2986-3001. PubMed ID: 29790963
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Glycogen synthase kinase 3β suppresses polyglutamine aggregation by inhibiting Vaccinia-related kinase 2 activity.
    Lee E; Ryu HG; Kim S; Lee D; Jeong YH; Kim KT
    Sci Rep; 2016 Jul; 6():29097. PubMed ID: 27377031
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Kinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites.
    Scarabelli G; Grant BJ
    Biophys J; 2014 Nov; 107(9):2204-13. PubMed ID: 25418105
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Allosteric Communication Disrupted by a Small Molecule Binding to the Imidazole Glycerol Phosphate Synthase Protein-Protein Interface.
    Rivalta I; Lisi GP; Snoeberger NS; Manley G; Loria JP; Batista VS
    Biochemistry; 2016 Nov; 55(47):6484-6494. PubMed ID: 27797506
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases.
    Chopra N; Wales TE; Joseph RE; Boyken SE; Engen JR; Jernigan RL; Andreotti AH
    PLoS Comput Biol; 2016 Mar; 12(3):e1004826. PubMed ID: 27010561
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Understanding G Protein-Coupled Receptor Allostery via Molecular Dynamics Simulations: Implications for Drug Discovery.
    Basith S; Lee Y; Choi S
    Methods Mol Biol; 2018; 1762():455-472. PubMed ID: 29594786
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.
    Ma N; Lippert LG; Devamani T; Levy B; Lee S; Sandhu M; Vaidehi N; Sivaramakrishnan S
    Biochemistry; 2018 Nov; 57(45):6387-6390. PubMed ID: 30339352
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock.
    Botello-Smith WM; Alsamarah A; Chatterjee P; Xie C; Lacroix JJ; Hao J; Luo Y
    PLoS Comput Biol; 2017 Aug; 13(8):e1005711. PubMed ID: 28827795
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.