289 related articles for article (PubMed ID: 30949773)
21. Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules.
Cho JH; Johnson GV
J Neurochem; 2004 Jan; 88(2):349-58. PubMed ID: 14690523
[TBL] [Abstract][Full Text] [Related]
22. Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer.
Ahuja LG; Kornev AP; McClendon CL; Veglia G; Taylor SS
Proc Natl Acad Sci U S A; 2017 Feb; 114(6):E931-E940. PubMed ID: 28115705
[TBL] [Abstract][Full Text] [Related]
23. The binding and phosphorylation of Thr231 is critical for Tau's hyperphosphorylation and functional regulation by glycogen synthase kinase 3beta.
Lin YT; Cheng JT; Liang LC; Ko CY; Lo YK; Lu PJ
J Neurochem; 2007 Oct; 103(2):802-13. PubMed ID: 17680984
[TBL] [Abstract][Full Text] [Related]
24. Identification of two potential glycogen synthase kinase 3β inhibitors for the treatment of osteosarcoma.
Lu K; Wang X; Chen Y; Liang D; Luo H; Long L; Hu Z; Bao J
Acta Biochim Biophys Sin (Shanghai); 2018 May; 50(5):456-464. PubMed ID: 29546355
[TBL] [Abstract][Full Text] [Related]
25. How do mutations and allosteric inhibitors modulate caspase-7 activity? A molecular dynamics study.
Bingöl EN; Serçinoğlu O; Ozbek P
J Biomol Struct Dyn; 2019 Aug; 37(13):3456-3466. PubMed ID: 30175666
[TBL] [Abstract][Full Text] [Related]
26. Intrinsic Dynamics of the Binding Rail and Its Allosteric Effect in the Class I Histone Deacetylases.
Zhou J; Huang Y; Cheng C; Wang K; Wu R
J Chem Inf Model; 2017 Sep; 57(9):2309-2320. PubMed ID: 28805377
[TBL] [Abstract][Full Text] [Related]
27. Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs.
Balasubramaniam M; Mainali N; Bowroju SK; Atluri P; Penthala NR; Ayyadevera S; Crooks PA; Shmookler Reis RJ
Sci Rep; 2020 Oct; 10(1):18326. PubMed ID: 33110096
[TBL] [Abstract][Full Text] [Related]
28. Xanthone glucoside 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one binds to the ATP-binding pocket of glycogen synthase kinase 3β and inhibits its activity: implications in prostate cancer and associated cardiovascular disease risk.
Mangangcha IR; Brojen Singh RK; Lebeche D; Ali S
J Biomol Struct Dyn; 2022 Oct; 40(17):7868-7884. PubMed ID: 33769184
[TBL] [Abstract][Full Text] [Related]
29. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.
Dajani R; Fraser E; Roe SM; Yeo M; Good VM; Thompson V; Dale TC; Pearl LH
EMBO J; 2003 Feb; 22(3):494-501. PubMed ID: 12554650
[TBL] [Abstract][Full Text] [Related]
30. MD simulations indicate Omicron P132H of SARS-CoV-2 M
Bhat ZA; Khan MM; Rehman A; Iqbal J; Sanjeev BS; Madhumalar A
Int J Biol Macromol; 2024 Mar; 262(Pt 2):130077. PubMed ID: 38346625
[TBL] [Abstract][Full Text] [Related]
31. Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.
James KA; Verkhivker GM
PLoS One; 2014; 9(11):e113488. PubMed ID: 25427151
[TBL] [Abstract][Full Text] [Related]
32. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Keedy DA; Hill ZB; Biel JT; Kang E; Rettenmaier TJ; Brandão-Neto J; Pearce NM; von Delft F; Wells JA; Fraser JS
Elife; 2018 Jun; 7():. PubMed ID: 29877794
[TBL] [Abstract][Full Text] [Related]
33. The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport.
Banerjee R; Rudloff Z; Naylor C; Yu MC; Gunawardena S
Hum Mol Genet; 2018 Sep; 27(17):2986-3001. PubMed ID: 29790963
[TBL] [Abstract][Full Text] [Related]
34. Glycogen synthase kinase 3β suppresses polyglutamine aggregation by inhibiting Vaccinia-related kinase 2 activity.
Lee E; Ryu HG; Kim S; Lee D; Jeong YH; Kim KT
Sci Rep; 2016 Jul; 6():29097. PubMed ID: 27377031
[TBL] [Abstract][Full Text] [Related]
35. Kinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites.
Scarabelli G; Grant BJ
Biophys J; 2014 Nov; 107(9):2204-13. PubMed ID: 25418105
[TBL] [Abstract][Full Text] [Related]
36. Allosteric Communication Disrupted by a Small Molecule Binding to the Imidazole Glycerol Phosphate Synthase Protein-Protein Interface.
Rivalta I; Lisi GP; Snoeberger NS; Manley G; Loria JP; Batista VS
Biochemistry; 2016 Nov; 55(47):6484-6494. PubMed ID: 27797506
[TBL] [Abstract][Full Text] [Related]
37. Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases.
Chopra N; Wales TE; Joseph RE; Boyken SE; Engen JR; Jernigan RL; Andreotti AH
PLoS Comput Biol; 2016 Mar; 12(3):e1004826. PubMed ID: 27010561
[TBL] [Abstract][Full Text] [Related]
38. Understanding G Protein-Coupled Receptor Allostery via Molecular Dynamics Simulations: Implications for Drug Discovery.
Basith S; Lee Y; Choi S
Methods Mol Biol; 2018; 1762():455-472. PubMed ID: 29594786
[TBL] [Abstract][Full Text] [Related]
39. Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.
Ma N; Lippert LG; Devamani T; Levy B; Lee S; Sandhu M; Vaidehi N; Sivaramakrishnan S
Biochemistry; 2018 Nov; 57(45):6387-6390. PubMed ID: 30339352
[TBL] [Abstract][Full Text] [Related]
40. Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock.
Botello-Smith WM; Alsamarah A; Chatterjee P; Xie C; Lacroix JJ; Hao J; Luo Y
PLoS Comput Biol; 2017 Aug; 13(8):e1005711. PubMed ID: 28827795
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]