These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 30954578)

  • 1. Inhibition of human 3-hydroxy-3-methylglutaryl CoA reductase by peptides leading to cholesterol homeostasis through SREBP2 pathway in HepG2 cells.
    Kumar V; Sharma P; Bairagya HR; Sharma S; Singh TP; Tiku PK
    Biochim Biophys Acta Proteins Proteom; 2019 Jun; 1867(6):604-615. PubMed ID: 30954578
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bisphenol A induces cholesterol biosynthesis in HepG2 cells via SREBP-2/HMGCR signaling pathway.
    Li Q; Zhang H; Zou J; Feng X; Feng D
    J Toxicol Sci; 2019; 44(7):481-491. PubMed ID: 31270304
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-185-5p mediates regulation of SREBP2 expression by hepatitis C virus core protein.
    Li M; Wang Q; Liu SA; Zhang JQ; Ju W; Quan M; Feng SH; Dong JL; Gao P; Cheng J
    World J Gastroenterol; 2015 Apr; 21(15):4517-25. PubMed ID: 25914460
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MMAB promotes negative feedback control of cholesterol homeostasis.
    Goedeke L; Canfrán-Duque A; Rotllan N; Chaube B; Thompson BM; Lee RG; Cline GW; McDonald JG; Shulman GI; Lasunción MA; Suárez Y; Fernández-Hernando C
    Nat Commun; 2021 Nov; 12(1):6448. PubMed ID: 34750386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism.
    Yu CY; Theusch E; Lo K; Mangravite LM; Naidoo D; Kutilova M; Medina MW
    Hum Mol Genet; 2014 Jan; 23(2):319-32. PubMed ID: 24001602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pro-inflammation NF-κB signaling triggers a positive feedback via enhancing cholesterol accumulation in liver cancer cells.
    He M; Zhang W; Dong Y; Wang L; Fang T; Tang W; Lv B; Chen G; Yang B; Huang P; Xia J
    J Exp Clin Cancer Res; 2017 Jan; 36(1):15. PubMed ID: 28100270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lupin peptides lower low-density lipoprotein (LDL) cholesterol through an up-regulation of the LDL receptor/sterol regulatory element binding protein 2 (SREBP2) pathway at HepG2 cell line.
    Lammi C; Zanoni C; Scigliuolo GM; D'Amato A; Arnoldi A
    J Agric Food Chem; 2014 Jul; 62(29):7151-9. PubMed ID: 24972343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis.
    Howe V; Sharpe LJ; Prabhu AV; Brown AJ
    Biochim Biophys Acta Mol Cell Biol Lipids; 2017 Jul; 1862(7):647-657. PubMed ID: 28342963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin.
    Trapani L; Segatto M; Simeoni V; Balducci V; Dhawan A; Parmar VS; Prasad AK; Saso L; Incerpi S; Pallottini V
    Biochimie; 2011 Jul; 93(7):1165-71. PubMed ID: 21530605
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation.
    Li LC; Varghese Z; Moorhead JF; Lee CT; Chen JB; Ruan XZ
    Am J Physiol Heart Circ Physiol; 2013 Mar; 304(6):H874-84. PubMed ID: 23335792
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-SREBP2 Provides a Mechanism for Dynamic Control of Cellular Cholesterol Homeostasis.
    Ozkan-Nikitaras T; Grzesik DJ; Romano LEL; Chapple JP; King PJ; Shoulders CC
    Cells; 2024 Jul; 13(15):. PubMed ID: 39120286
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deferoxamine stimulates LDLR expression and LDL uptake in HepG2 cells.
    Guillemot J; Asselin MC; Susan-Resiga D; Essalmani R; Seidah NG
    Mol Nutr Food Res; 2016 Mar; 60(3):600-8. PubMed ID: 26577249
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
    Loregger A; Raaben M; Tan J; Scheij S; Moeton M; van den Berg M; Gelberg-Etel H; Stickel E; Roitelman J; Brummelkamp T; Zelcer N
    Arterioscler Thromb Vasc Biol; 2017 Nov; 37(11):2064-2074. PubMed ID: 28882874
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis.
    Meng C; Zhou L; Huang L; Gu Q; Du X; Wang C; Liu F; Xia C
    Phytomedicine; 2024 Jan; 123():155271. PubMed ID: 38103317
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver.
    Hwang S; Hartman IZ; Calhoun LN; Garland K; Young GA; Mitsche MA; McDonald J; Xu F; Engelking L; DeBose-Boyd RA
    J Biol Chem; 2016 Jun; 291(26):13479-94. PubMed ID: 27129778
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase.
    Faulkner RA; Yang Y; Tsien J; Qin T; DeBose-Boyd RA
    Proc Natl Acad Sci U S A; 2024 Feb; 121(7):e2318822121. PubMed ID: 38319967
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulatory effect of Phikud Navakot extract on HMG-CoA reductase and LDL-R: potential and alternate agents for lowering blood cholesterol.
    Tirawanchai N; Supapornhemin S; Somkasetrin A; Suktitipat B; Ampawong S
    BMC Complement Altern Med; 2018 Sep; 18(1):258. PubMed ID: 30249222
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Negative feedback loop of cholesterol regulation is impaired in the livers of patients with Alagille syndrome.
    Miyahara Y; Bessho K; Kondou H; Hasegawa Y; Yasuda K; Ida S; Ihara Y; Mizuta K; Miyoshi Y; Ozono K
    Clin Chim Acta; 2015 Feb; 440():49-54. PubMed ID: 25444747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages.
    Sakai K; Nagashima S; Wakabayashi T; Tumenbayar B; Hayakawa H; Hayakawa M; Karasawa T; Ohashi K; Yamazaki H; Takei A; Takei S; Yamamuro D; Takahashi M; Yagyu H; Osuga JI; Takahashi M; Tominaga SI; Ishibashi S
    Arterioscler Thromb Vasc Biol; 2018 Nov; 38(11):2590-2600. PubMed ID: 30354246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.
    Chen H; Qi X; Faulkner RA; Schumacher MM; Donnelly LM; DeBose-Boyd RA; Li X
    Nat Commun; 2022 Jul; 13(1):4273. PubMed ID: 35879350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.