BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

439 related articles for article (PubMed ID: 30956116)

  • 1. Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.
    Quinn PM; Buck TM; Mulder AA; Ohonin C; Alves CH; Vos RM; Bialecka M; van Herwaarden T; van Dijk EHC; Talib M; Freund C; Mikkers HMM; Hoeben RC; Goumans MJ; Boon CJF; Koster AJ; Chuva de Sousa Lopes SM; Jost CR; Wijnholds J
    Stem Cell Reports; 2019 May; 12(5):906-919. PubMed ID: 30956116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in
    Boon N; Alves CH; Mulder AA; Andriessen CA; Buck TM; Quinn PMJ; Vos RM; Koster AJ; Jost CR; Wijnholds J
    Int J Mol Sci; 2021 Mar; 22(7):. PubMed ID: 33808129
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice.
    Pellissier LP; Lundvig DM; Tanimoto N; Klooster J; Vos RM; Richard F; Sothilingam V; Garcia Garrido M; Le Bivic A; Seeliger MW; Wijnholds J
    Hum Mol Genet; 2014 Jul; 23(14):3759-71. PubMed ID: 24565864
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype.
    Quinn PM; Mulder AA; Henrique Alves C; Desrosiers M; de Vries SI; Klooster J; Dalkara D; Koster AJ; Jost CR; Wijnholds J
    Hum Mol Genet; 2019 Jan; 28(1):105-123. PubMed ID: 30239717
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.
    van Rossum AG; Aartsen WM; Meuleman J; Klooster J; Malysheva A; Versteeg I; Arsanto JP; Le Bivic A; Wijnholds J
    Hum Mol Genet; 2006 Sep; 15(18):2659-72. PubMed ID: 16885194
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype.
    Boon N; Lu X; Andriessen CA; Moustakas I; Buck TM; Freund C; Arendzen CH; Böhringer S; Mei H; Wijnholds J
    Stem Cell Reports; 2023 May; 18(5):1123-1137. PubMed ID: 37084726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of CRB1 splicing in retinal organoids derived from a patient with adult-onset rod-cone dystrophy caused by the c.1892A>G and c.2548G>A variants.
    Zhang X; Thompson JA; Zhang D; Charng J; Arunachalam S; McLaren TL; Lamey TM; De Roach JN; Jennings L; McLenachan S; Chen FK
    Mol Genet Genomic Med; 2020 Nov; 8(11):e1489. PubMed ID: 32931148
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models.
    Pellissier LP; Quinn PM; Alves CH; Vos RM; Klooster J; Flannery JG; Heimel JA; Wijnholds J
    Hum Mol Genet; 2015 Jun; 24(11):3104-18. PubMed ID: 25701872
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.
    Alves CH; Pellissier LP; Vos RM; Garcia Garrido M; Sothilingam V; Seide C; Beck SC; Klooster J; Furukawa T; Flannery JG; Verhaagen J; Seeliger MW; Wijnholds J
    Hum Mol Genet; 2014 Jul; 23(13):3384-401. PubMed ID: 24493795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.
    Quinn PM; Alves CH; Klooster J; Wijnholds J
    Hum Mol Genet; 2018 Sep; 27(18):3137-3153. PubMed ID: 29893966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.
    Stehle IF; Imventarza JA; Woerz F; Hoffmann F; Boldt K; Beyer T; Quinn PM; Ueffing M
    Life Sci Alliance; 2024 Jun; 7(6):. PubMed ID: 38570189
    [No Abstract]   [Full Text] [Related]  

  • 12. Characterization and AAV-mediated
    Boon N; Lu X; Andriessen CA; Orlovà M; Quinn PMJ; Boon CJF; Wijnholds J
    Mol Ther Methods Clin Dev; 2023 Dec; 31():101128. PubMed ID: 37886604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids.
    Buck TM; Quinn PMJ; Pellissier LP; Mulder AA; Jongejan A; Lu X; Boon N; Koot D; Almushattat H; Arendzen CH; Vos RM; Bradley EJ; Freund C; Mikkers HMM; Boon CJF; Moerland PD; Baas F; Koster AJ; Neefjes J; Berlin I; Jost CR; Wijnholds J
    Stem Cell Reports; 2023 Sep; 18(9):1793-1810. PubMed ID: 37541258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
    Alves CH; Sanz AS; Park B; Pellissier LP; Tanimoto N; Beck SC; Huber G; Murtaza M; Richard F; Sridevi Gurubaran I; Garcia Garrido M; Levelt CN; Rashbass P; Le Bivic A; Seeliger MW; Wijnholds J
    Hum Mol Genet; 2013 Jan; 22(1):35-50. PubMed ID: 23001562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.
    Kantardzhieva A; Gosens I; Alexeeva S; Punte IM; Versteeg I; Krieger E; Neefjes-Mol CA; den Hollander AI; Letteboer SJ; Klooster J; Cremers FP; Roepman R; Wijnholds J
    Invest Ophthalmol Vis Sci; 2005 Jun; 46(6):2192-201. PubMed ID: 15914641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AAV-
    Buck TM; Vos RM; Alves CH; Wijnholds J
    Mol Ther Methods Clin Dev; 2021 Mar; 20():423-441. PubMed ID: 33575434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.
    van de Pavert SA; Kantardzhieva A; Malysheva A; Meuleman J; Versteeg I; Levelt C; Klooster J; Geiger S; Seeliger MW; Rashbass P; Le Bivic A; Wijnholds J
    J Cell Sci; 2004 Aug; 117(Pt 18):4169-77. PubMed ID: 15316081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells.
    Garita-Hernandez M; Routet F; Guibbal L; Khabou H; Toualbi L; Riancho L; Reichman S; Duebel J; Sahel JA; Goureau O; Dalkara D
    Int J Mol Sci; 2020 Feb; 21(3):. PubMed ID: 32028585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix.
    Felemban M; Dorgau B; Hunt NC; Hallam D; Zerti D; Bauer R; Ding Y; Collin J; Steel D; Krasnogor N; Al-Aama J; Lindsay S; Mellough C; Lako M
    Acta Biomater; 2018 Jul; 74():207-221. PubMed ID: 29777959
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.
    Pellissier LP; Alves CH; Quinn PM; Vos RM; Tanimoto N; Lundvig DM; Dudok JJ; Hooibrink B; Richard F; Beck SC; Huber G; Sothilingam V; Garcia Garrido M; Le Bivic A; Seeliger MW; Wijnholds J
    PLoS Genet; 2013; 9(12):e1003976. PubMed ID: 24339791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.