These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells. Ahmed ZSO; Li X; Li F; Cheaito HA; Patel K; Mosallam EM; Elbargeesy GAEH; Dou QP J Cell Biochem; 2018 Nov; 119(11):9006-9016. PubMed ID: 30015387 [TBL] [Abstract][Full Text] [Related]
3. Inhibition of Proteasomal Deubiquitinase by Silver Complex Induces Apoptosis in Non-Small Cell Lung Cancer Cells. Chen X; Yang Q; Chen J; Zhang P; Huang Q; Zhang X; Yang L; Xu D; Zhao C; Wang X; Liu J Cell Physiol Biochem; 2018; 49(2):780-797. PubMed ID: 30165348 [TBL] [Abstract][Full Text] [Related]
4. Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells. Chitta K; Paulus A; Akhtar S; Blake MK; Caulfield TR; Novak AJ; Ansell SM; Advani P; Ailawadhi S; Sher T; Linder S; Chanan-Khan A Br J Haematol; 2015 May; 169(3):377-90. PubMed ID: 25691154 [TBL] [Abstract][Full Text] [Related]
5. A ubiquitinome analysis to study the functional roles of the proteasome associated deubiquitinating enzymes USP14 and UCH37. van der Wal L; Bezstarosti K; Demmers JAA J Proteomics; 2022 Jun; 262():104592. PubMed ID: 35489684 [TBL] [Abstract][Full Text] [Related]
6. The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. Yun D; Zhuang Y; Kreutz MR; Behnisch T Neuropharmacology; 2018 May; 133():354-365. PubMed ID: 29407217 [TBL] [Abstract][Full Text] [Related]
7. Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells. Chadchankar J; Korboukh V; Conway LC; Wobst HJ; Walker CA; Doig P; Jacobsen SJ; Brandon NJ; Moss SJ; Wang Q PLoS One; 2019; 14(11):e0225145. PubMed ID: 31703099 [TBL] [Abstract][Full Text] [Related]
8. Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells. Ding W; Wang JX; Wu JZ; Liu AC; Jiang LL; Zhang HC; Meng Y; Liu BY; Peng GJ; Lou EZ; Mao Q; Zhou H; Tang DL; Chen X; Liu JB; Shi XP Acta Pharmacol Sin; 2023 Dec; 44(12):2537-2548. PubMed ID: 37528233 [TBL] [Abstract][Full Text] [Related]
9. Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase. Chen X; Wu J; Yang Q; Zhang X; Zhang P; Liao S; He Z; Wang X; Zhao C; Liu J Biometals; 2018 Feb; 31(1):29-43. PubMed ID: 29098502 [TBL] [Abstract][Full Text] [Related]
10. Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases. Zhao C; Chen X; Yang C; Zang D; Lan X; Liao S; Zhang P; Wu J; Li X; Liu N; Liao Y; Huang H; Shi X; Jiang L; Liu X; Dou QP; Wang X; Liu J Oncotarget; 2017 Feb; 8(8):13942-13956. PubMed ID: 28086217 [TBL] [Abstract][Full Text] [Related]
12. In vitro analysis of proteasome-associated USP14 activity for substrate degradation and deubiquitylation. Muniyappan S; Lee BH Methods Enzymol; 2019; 619():249-268. PubMed ID: 30910023 [TBL] [Abstract][Full Text] [Related]
13. Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies. Didier R; Mallavialle A; Ben Jouira R; Domdom MA; Tichet M; Auberger P; Luciano F; Ohanna M; Tartare-Deckert S; Deckert M Mol Cancer Ther; 2018 Jul; 17(7):1416-1429. PubMed ID: 29703842 [TBL] [Abstract][Full Text] [Related]
14. A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy. Zhao C; Chen X; Zang D; Lan X; Liao S; Yang C; Zhang P; Wu J; Li X; Liu N; Liao Y; Huang H; Shi X; Jiang L; Liu X; He Z; Dou QP; Wang X; Liu J Oncogene; 2016 Nov; 35(45):5916-5927. PubMed ID: 27086925 [TBL] [Abstract][Full Text] [Related]
15. Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth. Liu N; Li X; Huang H; Zhao C; Liao S; Yang C; Liu S; Song W; Lu X; Lan X; Chen X; Yi S; Xu L; Jiang L; Zhao C; Dong X; Zhou P; Li S; Wang S; Shi X; Dou PQ; Wang X; Liu J Oncotarget; 2014 Jul; 5(14):5453-71. PubMed ID: 24977961 [TBL] [Abstract][Full Text] [Related]
16. UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells. Kim HT; Goldberg AL Proc Natl Acad Sci U S A; 2018 Dec; 115(50):E11642-E11650. PubMed ID: 30487212 [TBL] [Abstract][Full Text] [Related]
17. Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells. Paulus A; Akhtar S; Caulfield TR; Samuel K; Yousaf H; Bashir Y; Paulus SM; Tran D; Hudec R; Cogen D; Jiang J; Edenfield B; Novak A; Ansell SM; Witzig T; Martin P; Coleman M; Roy V; Ailawadhi S; Chitta K; Linder S; Chanan-Khan A Blood Cancer J; 2016 Nov; 6(11):e492. PubMed ID: 27813535 [TBL] [Abstract][Full Text] [Related]
18. The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells. Wang X; Mazurkiewicz M; Hillert EK; Olofsson MH; Pierrou S; Hillertz P; Gullbo J; Selvaraju K; Paulus A; Akhtar S; Bossler F; Khan AC; Linder S; D'Arcy P Sci Rep; 2016 Jun; 6():26979. PubMed ID: 27264969 [TBL] [Abstract][Full Text] [Related]
19. Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. Vaden JH; Bhattacharyya BJ; Chen PC; Watson JA; Marshall AG; Phillips SE; Wilson JA; King GD; Miller RJ; Wilson SM Mol Neurodegener; 2015 Jan; 10():3. PubMed ID: 25575639 [TBL] [Abstract][Full Text] [Related]
20. Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor. Liao Y; Liu N; Hua X; Cai J; Xia X; Wang X; Huang H; Liu J Cell Death Dis; 2017 Feb; 8(2):e2585. PubMed ID: 28151478 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]