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4. Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial. DiNardo CD; Schuh AC; Stein EM; Montesinos P; Wei AH; de Botton S; Zeidan AM; Fathi AT; Kantarjian HM; Bennett JM; Frattini MG; Martin-Regueira P; Lersch F; Gong J; Hasan M; Vyas P; Döhner H Lancet Oncol; 2021 Nov; 22(11):1597-1608. PubMed ID: 34672961 [TBL] [Abstract][Full Text] [Related]
5. Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial. Stein EM; Fathi AT; DiNardo CD; Pollyea DA; Roboz GJ; Collins R; Sekeres MA; Stone RM; Attar EC; Frattini MG; Tosolini A; Xu Q; See WL; MacBeth KJ; de Botton S; Tallman MS; Kantarjian HM Lancet Haematol; 2020 Apr; 7(4):e309-e319. PubMed ID: 32145771 [TBL] [Abstract][Full Text] [Related]
6. Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy. Venugopal S; Takahashi K; Daver N; Maiti A; Borthakur G; Loghavi S; Short NJ; Ohanian M; Masarova L; Issa G; Wang X; Carlos BR; Yilmaz M; Kadia T; Andreeff M; Ravandi F; Konopleva M; Kantarjian HM; DiNardo CD Blood Cancer J; 2022 Jan; 12(1):10. PubMed ID: 35078972 [TBL] [Abstract][Full Text] [Related]
7. Differentiation Syndrome Associated With Enasidenib, a Selective Inhibitor of Mutant Isocitrate Dehydrogenase 2: Analysis of a Phase 1/2 Study. Fathi AT; DiNardo CD; Kline I; Kenvin L; Gupta I; Attar EC; Stein EM; de Botton S; JAMA Oncol; 2018 Aug; 4(8):1106-1110. PubMed ID: 29346478 [TBL] [Abstract][Full Text] [Related]
8. Enasidenib: First Mutant IDH2 Inhibitor for the Treatment of Refractory and Relapsed Acute Myeloid Leukemia. Dogra R; Bhatia R; Shankar R; Bansal P; Rawal RK Anticancer Agents Med Chem; 2018; 18(14):1936-1951. PubMed ID: 30360730 [TBL] [Abstract][Full Text] [Related]
9. Enasidenib, a targeted inhibitor of mutant IDH2 proteins for treatment of relapsed or refractory acute myeloid leukemia. Stein EM Future Oncol; 2018 Jan; 14(1):23-40. PubMed ID: 29243965 [TBL] [Abstract][Full Text] [Related]
10. Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. Intlekofer AM; Shih AH; Wang B; Nazir A; Rustenburg AS; Albanese SK; Patel M; Famulare C; Correa FM; Takemoto N; Durani V; Liu H; Taylor J; Farnoud N; Papaemmanuil E; Cross JR; Tallman MS; Arcila ME; Roshal M; Petsko GA; Wu B; Choe S; Konteatis ZD; Biller SA; Chodera JD; Thompson CB; Levine RL; Stein EM Nature; 2018 Jul; 559(7712):125-129. PubMed ID: 29950729 [TBL] [Abstract][Full Text] [Related]
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13. Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study. Stein EM; DiNardo CD; Fathi AT; Mims AS; Pratz KW; Savona MR; Stein AS; Stone RM; Winer ES; Seet CS; Döhner H; Pollyea DA; McCloskey JK; Odenike O; Löwenberg B; Ossenkoppele GJ; Patel PA; Roshal M; Frattini MG; Lersch F; Franovic A; Nabhan S; Fan B; Choe S; Wang H; Wu B; Hua L; Almon C; Cooper M; Kantarjian HM; Tallman MS Blood; 2021 Apr; 137(13):1792-1803. PubMed ID: 33024987 [TBL] [Abstract][Full Text] [Related]
14. All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells. Kim Y; Jeung HK; Cheong JW; Song J; Bae SH; Lee JI; Min YH Yonsei Med J; 2020 Sep; 61(9):762-773. PubMed ID: 32882760 [TBL] [Abstract][Full Text] [Related]
15. Differentiation syndrome associated with treatment with IDH2 inhibitor enasidenib: pooled analysis from clinical trials. Montesinos P; Fathi AT; de Botton S; Stein EM; Zeidan AM; Zhu Y; Prebet T; Vigil CE; Bluemmert I; Yu X; DiNardo CD Blood Adv; 2024 May; 8(10):2509-2519. PubMed ID: 38507688 [TBL] [Abstract][Full Text] [Related]
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17. Enasidenib. Krämer A; Bochtler T Recent Results Cancer Res; 2018; 212():187-197. PubMed ID: 30069631 [TBL] [Abstract][Full Text] [Related]
18. Enasidenib for patients with relapsed acute myeloid leukemia and the IDH2 mutation. DiNardo C Clin Adv Hematol Oncol; 2018 Apr; 16(4):247-249. PubMed ID: 29742078 [No Abstract] [Full Text] [Related]
19. IDH2 inhibition in AML: Finally progress? Stein EM Best Pract Res Clin Haematol; 2015; 28(2-3):112-5. PubMed ID: 26590767 [TBL] [Abstract][Full Text] [Related]
20. Enasidenib for the treatment of acute myeloid leukemia. Dugan J; Pollyea D Expert Rev Clin Pharmacol; 2018 Aug; 11(8):755-760. PubMed ID: 29770715 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]