146 related articles for article (PubMed ID: 30967630)
1. Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness.
Fadhlullah SFB; Halim NBA; Yeo JYT; Ho RLY; Um P; Ang BT; Tang C; Ng WH; Virshup DM; Ho IAW
Oncogene; 2019 Jul; 38(27):5367-5380. PubMed ID: 30967630
[TBL] [Abstract][Full Text] [Related]
2. Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival.
Pan Y; Smithson LJ; Ma Y; Hambardzumyan D; Gutmann DH
Oncotarget; 2017 May; 8(20):32977-32989. PubMed ID: 28380429
[TBL] [Abstract][Full Text] [Related]
3. Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells.
Harigai R; Sakai S; Nobusue H; Hirose C; Sampetrean O; Minami N; Hata Y; Kasama T; Hirose T; Takenouchi T; Kosaki K; Kishi K; Saya H; Arima Y
Sci Rep; 2018 Apr; 8(1):6069. PubMed ID: 29666462
[TBL] [Abstract][Full Text] [Related]
4. CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation.
Moutal A; Villa LS; Yeon SK; Householder KT; Park KD; Sirianni RW; Khanna R
Mol Neurobiol; 2018 May; 55(5):4403-4416. PubMed ID: 28660485
[TBL] [Abstract][Full Text] [Related]
5. Identifying the Ubiquitin Ligase complex that regulates the NF1 tumor suppressor and Ras.
Hollstein PE; Cichowski K
Cancer Discov; 2013 Aug; 3(8):880-93. PubMed ID: 23661552
[TBL] [Abstract][Full Text] [Related]
6.
Scheer M; Leisz S; Sorge E; Storozhuk O; Prell J; Ho I; Harder A
Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008787
[No Abstract] [Full Text] [Related]
7. Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.
Turbyville TJ; Gürsel DB; Tuskan RG; Walrath JC; Lipschultz CA; Lockett SJ; Wiemer DF; Beutler JA; Reilly KM
Mol Cancer Ther; 2010 May; 9(5):1234-43. PubMed ID: 20442305
[TBL] [Abstract][Full Text] [Related]
8. NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques C; Unterkircher T; Kroon P; Oldrini B; Izzo A; Dramaretska Y; Ferrarese R; Kling E; Schnell O; Nelander S; Wagner EF; Bakiri L; Gargiulo G; Carro MS; Squatrito M
Elife; 2021 Aug; 10():. PubMed ID: 34399888
[TBL] [Abstract][Full Text] [Related]
9. Clinicopathologic implications of NF1 gene alterations in diffuse gliomas.
Vizcaíno MA; Shah S; Eberhart CG; Rodriguez FJ
Hum Pathol; 2015 Sep; 46(9):1323-30. PubMed ID: 26190195
[TBL] [Abstract][Full Text] [Related]
10. Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis.
McGillicuddy LT; Fromm JA; Hollstein PE; Kubek S; Beroukhim R; De Raedt T; Johnson BW; Williams SM; Nghiemphu P; Liau LM; Cloughesy TF; Mischel PS; Parret A; Seiler J; Moldenhauer G; Scheffzek K; Stemmer-Rachamimov AO; Sawyers CL; Brennan C; Messiaen L; Mellinghoff IK; Cichowski K
Cancer Cell; 2009 Jul; 16(1):44-54. PubMed ID: 19573811
[TBL] [Abstract][Full Text] [Related]
11. Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1.
Hirata Y; Brems H; Suzuki M; Kanamori M; Okada M; Morita R; Llano-Rivas I; Ose T; Messiaen L; Legius E; Yoshimura A
J Biol Chem; 2016 Feb; 291(7):3124-34. PubMed ID: 26635368
[TBL] [Abstract][Full Text] [Related]
12. Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.
Yunoue S; Tokuo H; Fukunaga K; Feng L; Ozawa T; Nishi T; Kikuchi A; Hattori S; Kuratsu J; Saya H; Araki N
J Biol Chem; 2003 Jul; 278(29):26958-69. PubMed ID: 12730209
[TBL] [Abstract][Full Text] [Related]
13. Pathogenic Mutations Associated with Legius Syndrome Modify the Spred1 Surface and Are Involved in Direct Binding to the Ras Inactivator Neurofibromin.
Führer S; Tollinger M; Dunzendorfer-Matt T
J Mol Biol; 2019 Sep; 431(19):3889-3899. PubMed ID: 31401120
[TBL] [Abstract][Full Text] [Related]
14. Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro.
Wood MD; Mukherjee J; Pieper RO
Sci Rep; 2018 Apr; 8(1):5805. PubMed ID: 29643433
[TBL] [Abstract][Full Text] [Related]
15. A novel neurofibromin (NF1) interaction with the leucine-rich pentatricopeptide repeat motif-containing protein links neurofibromatosis type 1 and the French Canadian variant of Leigh's syndrome in a common molecular complex.
Arun V; Wiley JC; Kaur H; Kaplan DR; Guha A
J Neurosci Res; 2013 Apr; 91(4):494-505. PubMed ID: 23361976
[TBL] [Abstract][Full Text] [Related]
16. The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.
Solga AC; Toonen JA; Pan Y; Cimino PJ; Ma Y; Castillon GA; Gianino SM; Ellisman MH; Lee DY; Gutmann DH
Oncotarget; 2017 Jul; 8(29):47206-47215. PubMed ID: 28525381
[TBL] [Abstract][Full Text] [Related]
17. The pre-GAP-related domain of neurofibromin regulates cell migration through the LIM kinase/cofilin pathway.
Starinsky-Elbaz S; Faigenbloom L; Friedman E; Stein R; Kloog Y
Mol Cell Neurosci; 2009 Dec; 42(4):278-87. PubMed ID: 19666124
[TBL] [Abstract][Full Text] [Related]
18. A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma.
Way GP; Allaway RJ; Bouley SJ; Fadul CE; Sanchez Y; Greene CS
BMC Genomics; 2017 Feb; 18(1):127. PubMed ID: 28166733
[TBL] [Abstract][Full Text] [Related]
19. Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.
Yzaguirre AD; Padmanabhan A; de Groh ED; Engleka KA; Li J; Speck NA; Epstein JA
Elife; 2015 Oct; 4():e07780. PubMed ID: 26460546
[TBL] [Abstract][Full Text] [Related]
20. Sensitivity of glioblastomas to clinically available MEK inhibitors is defined by neurofibromin 1 deficiency.
See WL; Tan IL; Mukherjee J; Nicolaides T; Pieper RO
Cancer Res; 2012 Jul; 72(13):3350-9. PubMed ID: 22573716
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]