BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 30975033)

  • 1. RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR.
    Lyu K; Kumagai A; Dunphy WG
    Cell Cycle; 2019 Apr; 18(8):898-913. PubMed ID: 30975033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of the ATR kinase by the RPA-binding protein ETAA1.
    Haahr P; Hoffmann S; Tollenaere MA; Ho T; Toledo LI; Mann M; Bekker-Jensen S; Räschle M; Mailand N
    Nat Cell Biol; 2016 Nov; 18(11):1196-1207. PubMed ID: 27723717
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATR activation is regulated by dimerization of ATR activating proteins.
    Thada V; Cortez D
    J Biol Chem; 2021; 296():100455. PubMed ID: 33636182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.
    Choi JH; Lindsey-Boltz LA; Kemp M; Mason AC; Wold MS; Sancar A
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13660-5. PubMed ID: 20616048
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.
    Zhang H; Head PE; Daddacha W; Park SH; Li X; Pan Y; Madden MZ; Duong DM; Xie M; Yu B; Warren MD; Liu EA; Dhere VR; Li C; Pradilla I; Torres MA; Wang Y; Dynan WS; Doetsch PW; Deng X; Seyfried NT; Gius D; Yu DS
    Cell Rep; 2016 Feb; 14(6):1435-1447. PubMed ID: 26854234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation.
    Ball HL; Myers JS; Cortez D
    Mol Biol Cell; 2005 May; 16(5):2372-81. PubMed ID: 15743907
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
    Zou L; Elledge SJ
    Science; 2003 Jun; 300(5625):1542-8. PubMed ID: 12791985
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ETAA1 acts at stalled replication forks to maintain genome integrity.
    Bass TE; Luzwick JW; Kavanaugh G; Carroll C; Dungrawala H; Glick GG; Feldkamp MD; Putney R; Chazin WJ; Cortez D
    Nat Cell Biol; 2016 Nov; 18(11):1185-1195. PubMed ID: 27723720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP.
    Kim SM; Kumagai A; Lee J; Dunphy WG
    J Biol Chem; 2005 Nov; 280(46):38355-64. PubMed ID: 16186122
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APE1 recruits ATRIP to ssDNA in an RPA-dependent and -independent manner to promote the ATR DNA damage response.
    Lin Y; Li J; Zhao H; McMahon A; McGhee K; Yan S
    Elife; 2023 May; 12():. PubMed ID: 37216274
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress.
    Ackerson SM; Gable CI; Stewart JA
    Cell Cycle; 2020 Dec; 19(24):3491-3507. PubMed ID: 33269665
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATR autophosphorylation as a molecular switch for checkpoint activation.
    Liu S; Shiotani B; Lahiri M; Maréchal A; Tse A; Leung CC; Glover JN; Yang XH; Zou L
    Mol Cell; 2011 Jul; 43(2):192-202. PubMed ID: 21777809
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.
    Kar A; Kaur M; Ghosh T; Khan MM; Sharma A; Shekhar R; Varshney A; Saxena S
    Nucleic Acids Res; 2015 May; 43(10):4962-74. PubMed ID: 25916848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1.
    Kumagai A; Kim SM; Dunphy WG
    J Biol Chem; 2004 Nov; 279(48):49599-608. PubMed ID: 15371427
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response.
    Lee YC; Zhou Q; Chen J; Yuan J
    Curr Biol; 2016 Dec; 26(24):3257-3268. PubMed ID: 27818175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATRIP associates with replication protein A-coated ssDNA through multiple interactions.
    Namiki Y; Zou L
    Proc Natl Acad Sci U S A; 2006 Jan; 103(3):580-5. PubMed ID: 16407120
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
    Maréchal A; Li JM; Ji XY; Wu CS; Yazinski SA; Nguyen HD; Liu S; Jiménez AE; Jin J; Zou L
    Mol Cell; 2014 Jan; 53(2):235-246. PubMed ID: 24332808
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of ATR-related protein kinase upon DNA damage recognition.
    Ma M; Rodriguez A; Sugimoto K
    Curr Genet; 2020 Apr; 66(2):327-333. PubMed ID: 31624858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.
    Biswas H; Goto G; Wang W; Sung P; Sugimoto K
    PLoS Genet; 2019 Aug; 15(8):e1008294. PubMed ID: 31369547
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
    Willis J; Patel Y; Lentz BL; Yan S
    Proc Natl Acad Sci U S A; 2013 Jun; 110(26):10592-7. PubMed ID: 23754435
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.