These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 30975898)

  • 1. Mechanism of frataxin "bypass" in human iron-sulfur cluster biosynthesis with implications for Friedreich's ataxia.
    Das D; Patra S; Bridwell-Rabb J; Barondeau DP
    J Biol Chem; 2019 Jun; 294(23):9276-9284. PubMed ID: 30975898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of activation of the human cysteine desulfurase complex by frataxin.
    Patra S; Barondeau DP
    Proc Natl Acad Sci U S A; 2019 Sep; 116(39):19421-19430. PubMed ID: 31511419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-function analysis of Friedreich's ataxia mutants reveals determinants of frataxin binding and activation of the Fe-S assembly complex.
    Bridwell-Rabb J; Winn AM; Barondeau DP
    Biochemistry; 2011 Aug; 50(33):7265-74. PubMed ID: 21776984
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity.
    Fox NG; Martelli A; Nabhan JF; Janz J; Borkowska O; Bulawa C; Yue WW
    Biochimie; 2018 Sep; 152():211-218. PubMed ID: 30031876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
    Cory SA; Van Vranken JG; Brignole EJ; Patra S; Winge DR; Drennan CL; Rutter J; Barondeau DP
    Proc Natl Acad Sci U S A; 2017 Jul; 114(27):E5325-E5334. PubMed ID: 28634302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry.
    Bridwell-Rabb J; Fox NG; Tsai CL; Winn AM; Barondeau DP
    Biochemistry; 2014 Aug; 53(30):4904-13. PubMed ID: 24971490
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Friedreich's ataxia variants I154F and W155R diminish frataxin-based activation of the iron-sulfur cluster assembly complex.
    Tsai CL; Bridwell-Rabb J; Barondeau DP
    Biochemistry; 2011 Jul; 50(29):6478-87. PubMed ID: 21671584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Human Iron-Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules.
    Fox NG; Chakrabarti M; McCormick SP; Lindahl PA; Barondeau DP
    Biochemistry; 2015 Jun; 54(25):3871-9. PubMed ID: 26016389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2.
    Schulz V; Steinhilper R; Oltmanns J; Freibert SA; Krapoth N; Linne U; Welsch S; Hoock MH; Schünemann V; Murphy BJ; Lill R
    Nat Commun; 2024 Apr; 15(1):3269. PubMed ID: 38627381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
    Fox NG; Yu X; Feng X; Bailey HJ; Martelli A; Nabhan JF; Strain-Damerell C; Bulawa C; Yue WW; Han S
    Nat Commun; 2019 May; 10(1):2210. PubMed ID: 31101807
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly.
    Cai K; Frederick RO; Tonelli M; Markley JL
    J Inorg Biochem; 2018 Jun; 183():107-116. PubMed ID: 29576242
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin.
    Gervason S; Larkem D; Mansour AB; Botzanowski T; Müller CS; Pecqueur L; Le Pavec G; Delaunay-Moisan A; Brun O; Agramunt J; Grandas A; Fontecave M; Schünemann V; Cianférani S; Sizun C; Tolédano MB; D'Autréaux B
    Nat Commun; 2019 Aug; 10(1):3566. PubMed ID: 31395877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis.
    Bridwell-Rabb J; Iannuzzi C; Pastore A; Barondeau DP
    Biochemistry; 2012 Mar; 51(12):2506-14. PubMed ID: 22352884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly.
    Gakh O; Bedekovics T; Duncan SF; Smith DY; Berkholz DS; Isaya G
    J Biol Chem; 2010 Dec; 285(49):38486-501. PubMed ID: 20889968
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex.
    Fox NG; Das D; Chakrabarti M; Lindahl PA; Barondeau DP
    Biochemistry; 2015 Jun; 54(25):3880-9. PubMed ID: 26016518
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly.
    Pandey A; Gordon DM; Pain J; Stemmler TL; Dancis A; Pain D
    J Biol Chem; 2013 Dec; 288(52):36773-86. PubMed ID: 24217246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of Mitochondrial Iron-Sulfur Protein Biogenesis.
    Lill R; Freibert SA
    Annu Rev Biochem; 2020 Jun; 89():471-499. PubMed ID: 31935115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.
    Shan Y; Napoli E; Cortopassi G
    Hum Mol Genet; 2007 Apr; 16(8):929-41. PubMed ID: 17331979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex.
    Tsai CL; Barondeau DP
    Biochemistry; 2010 Nov; 49(43):9132-9. PubMed ID: 20873749
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Details of the Frataxin-Scaffold Interaction during Mitochondrial Fe-S Cluster Assembly.
    Campbell CJ; Pall AE; Naik AR; Thompson LN; Stemmler TL
    Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34199378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.