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3. Condensation of the β-cell secretory granule luminal cargoes pro/insulin and ICA512 RESP18 homology domain. Toledo PL; Vazquez DS; Gianotti AR; Abate MB; Wegbrod C; Torkko JM; Solimena M; Ermácora MR Protein Sci; 2023 Jun; 32(6):e4649. PubMed ID: 37159024 [TBL] [Abstract][Full Text] [Related]
4. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum. Torkko JM; Primo ME; Dirkx R; Friedrich A; Viehrig A; Vergari E; Borgonovo B; Sönmez A; Wegbrod C; Lachnit M; Münster C; Sica MP; Ermácora MR; Solimena M Mol Cell Biol; 2015 Mar; 35(6):914-27. PubMed ID: 25561468 [TBL] [Abstract][Full Text] [Related]
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6. ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs. Mziaut H; Kersting S; Knoch KP; Fan WH; Trajkovski M; Erdmann K; Bergert H; Ehehalt F; Saeger HD; Solimena M Proc Natl Acad Sci U S A; 2008 Jan; 105(2):674-9. PubMed ID: 18178618 [TBL] [Abstract][Full Text] [Related]
7. Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells. Trajkovski M; Mziaut H; Altkrüger A; Ouwendijk J; Knoch KP; Müller S; Solimena M J Cell Biol; 2004 Dec; 167(6):1063-74. PubMed ID: 15596545 [TBL] [Abstract][Full Text] [Related]
8. The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512. Mziaut H; Mulligan B; Hoboth P; Otto O; Ivanova A; Herbig M; Schumann D; Hildebrandt T; Dehghany J; Sönmez A; Münster C; Meyer-Hermann M; Guck J; Kalaidzidis Y; Solimena M Mol Metab; 2016 Aug; 5(8):656-668. PubMed ID: 27656403 [TBL] [Abstract][Full Text] [Related]
9. Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion. Ort T; Voronov S; Guo J; Zawalich K; Froehner SC; Zawalich W; Solimena M EMBO J; 2001 Aug; 20(15):4013-23. PubMed ID: 11483505 [TBL] [Abstract][Full Text] [Related]
10. The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. Ort T; Maksimova E; Dirkx R; Kachinsky AM; Berghs S; Froehner SC; Solimena M Eur J Cell Biol; 2000 Sep; 79(9):621-30. PubMed ID: 11043403 [TBL] [Abstract][Full Text] [Related]
11. RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose. Zhang G; Hirai H; Cai T; Miura J; Yu P; Huang H; Schiller MR; Swaim WD; Leapman RD; Notkins AL J Endocrinol; 2007 Nov; 195(2):313-21. PubMed ID: 17951542 [TBL] [Abstract][Full Text] [Related]
12. Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules. Hermel JM; Dirkx R; Solimena M Eur J Neurosci; 1999 Aug; 11(8):2609-20. PubMed ID: 10457160 [TBL] [Abstract][Full Text] [Related]
13. Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2. Kawasaki E; Eisenbarth GS; Wasmeier C; Hutton JC Diabetes; 1996 Oct; 45(10):1344-9. PubMed ID: 8826969 [TBL] [Abstract][Full Text] [Related]
14. Stabilization of the receptor protein tyrosine phosphatase-like protein ICA512 in GH4C1 cells upon treatment with estradiol, insulin, and epidermal growth factor. Lee MS; Dirkx R; Solimena M; Dannies PS Endocrinology; 1998 Jun; 139(6):2727-33. PubMed ID: 9607778 [TBL] [Abstract][Full Text] [Related]
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