402 related articles for article (PubMed ID: 30981113)
21. Design, synthesis and biological evaluation of novel benzimidazole-2-substituted phenyl or pyridine propyl ketene derivatives as antitumour agents.
Wu LT; Jiang Z; Shen JJ; Yi H; Zhan YC; Sha MQ; Wang Z; Xue ST; Li ZR
Eur J Med Chem; 2016 May; 114():328-36. PubMed ID: 27017265
[TBL] [Abstract][Full Text] [Related]
22. One-pot synthesis of spiro(indoline-3,4'-pyrazolo[3,4-b]pyridine)-5'-carbonitriles as p53-MDM2 interaction inhibitors.
Ibrahim HS; Eldehna WM; Fallacara AL; Ahmed ER; Ghabbour HA; Elaasser MM; Botta M; Abou-Seri SM; Abdel-Aziz HA
Future Med Chem; 2018 Dec; 10(24):2771-2789. PubMed ID: 30526032
[TBL] [Abstract][Full Text] [Related]
23. Design, synthesis and biological evaluation of novel antitumor spirotetrahydrothiopyran-oxindole derivatives as potent p53-MDM2 inhibitors.
Ji C; Wang S; Chen S; He S; Jiang Y; Miao Z; Li J; Sheng C
Bioorg Med Chem; 2017 Oct; 25(20):5268-5277. PubMed ID: 28797774
[TBL] [Abstract][Full Text] [Related]
24. Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction.
Zhuang C; Miao Z; Zhu L; Dong G; Guo Z; Wang S; Zhang Y; Wu Y; Yao J; Sheng C; Zhang W
J Med Chem; 2012 Nov; 55(22):9630-42. PubMed ID: 23046248
[TBL] [Abstract][Full Text] [Related]
25. Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway.
Bao R; Shu Y; Wu X; Weng H; Ding Q; Cao Y; Li M; Mu J; Wu W; Ding Q; Tan Z; Liu T; Jiang L; Hu Y; Gu J; Liu Y
BMC Cancer; 2014 Mar; 14():217. PubMed ID: 24655726
[TBL] [Abstract][Full Text] [Related]
26. Synthesis and Cytotoxicity Assessment of Novel 7-O- and 14-O-Derivatives of Glaucocalyxin A.
Liu HC; Qiao LM; Zheng W; Xiang ZB; Chen HS; Yu SC; Zhang DZ; Wang T; Zhang YF; Jin YS
Anticancer Agents Med Chem; 2020; 20(10):1241-1249. PubMed ID: 32116205
[TBL] [Abstract][Full Text] [Related]
27. 2-Styryl-4-aminoquinazoline derivatives as potent DNA-cleavage, p53-activation and in vivo effective anticancer agents.
Wei XW; Yuan JM; Huang WY; Chen NY; Li XJ; Pan CX; Mo DL; Su GF
Eur J Med Chem; 2020 Jan; 186():111851. PubMed ID: 31761381
[TBL] [Abstract][Full Text] [Related]
28. Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to Mitochondria.
Xu S; Luo S; Yao H; Cai H; Miao X; Wu F; Yang DH; Wu X; Xie W; Yao H; Chen ZS; Xu J
J Med Chem; 2016 May; 59(10):5022-34. PubMed ID: 27089099
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents.
Yang J; Liu Y; Xue C; Yu W; Zhang J; Qiao C
Eur J Med Chem; 2014 Oct; 86():235-41. PubMed ID: 25164762
[TBL] [Abstract][Full Text] [Related]
30. MDM2 small-molecule antagonist RG7112 activates p53 signaling and regresses human tumors in preclinical cancer models.
Tovar C; Graves B; Packman K; Filipovic Z; Higgins B; Xia M; Tardell C; Garrido R; Lee E; Kolinsky K; To KH; Linn M; Podlaski F; Wovkulich P; Vu B; Vassilev LT
Cancer Res; 2013 Apr; 73(8):2587-97. PubMed ID: 23400593
[TBL] [Abstract][Full Text] [Related]
31. Inhibiting MDM2-p53 Interaction Suppresses Tumor Growth in Patient-Derived Non-Small Cell Lung Cancer Xenograft Models.
Hai J; Sakashita S; Allo G; Ludkovski O; Ng C; Shepherd FA; Tsao MS
J Thorac Oncol; 2015 Aug; 10(8):1172-80. PubMed ID: 26200271
[TBL] [Abstract][Full Text] [Related]
32. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Zhou GB; Kang H; Wang L; Gao L; Liu P; Xie J; Zhang FX; Weng XQ; Shen ZX; Chen J; Gu LJ; Yan M; Zhang DE; Chen SJ; Wang ZY; Chen Z
Blood; 2007 Apr; 109(8):3441-50. PubMed ID: 17197433
[TBL] [Abstract][Full Text] [Related]
33. Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 2.
Wang W; Lv D; Qiu N; Zhang L; Hu C; Hu Y
Bioorg Med Chem; 2013 Jun; 21(11):2886-94. PubMed ID: 23611770
[TBL] [Abstract][Full Text] [Related]
34. Oridonin effectively reverses cisplatin drug resistance in human ovarian cancer cells via induction of cell apoptosis and inhibition of matrix metalloproteinase expression.
Ma S; Tan W; Du B; Liu W; Li W; Che D; Zhang G
Mol Med Rep; 2016 Apr; 13(4):3342-8. PubMed ID: 26935490
[TBL] [Abstract][Full Text] [Related]
35. Proapoptotic modification of substituted isoindolinones as MDM2-p53 inhibitors.
Grigoreva TA; Novikova DS; Petukhov AV; Gureev MA; Garabadzhiu AV; Melino G; Barlev NA; Tribulovich VG
Bioorg Med Chem Lett; 2017 Dec; 27(23):5197-5202. PubMed ID: 29089230
[TBL] [Abstract][Full Text] [Related]
36. Oridonin enhances antitumor activity of gemcitabine in pancreatic cancer through MAPK-p38 signaling pathway.
Bu HQ; Luo J; Chen H; Zhang JH; Li HH; Guo HC; Wang ZH; Lin SZ
Int J Oncol; 2012 Sep; 41(3):949-58. PubMed ID: 22710877
[TBL] [Abstract][Full Text] [Related]
37. Hydrogen sulfide donating ent-kaurane and spirolactone-type 6,7-seco-ent-kaurane derivatives: Design, synthesis and antiproliferative properties.
Li H; Gao X; Huang X; Wang X; Xu S; Uchita T; Gao M; Xu J; Hua H; Li D
Eur J Med Chem; 2019 Sep; 178():446-457. PubMed ID: 31202992
[TBL] [Abstract][Full Text] [Related]
38. Synthesis of spirolactone-type diterpenoid derivatives from kaurene-type oridonin with improved antiproliferative effects and their apoptosis-inducing activity in human hepatoma Bel-7402 cells.
Li D; Cai H; Jiang B; Liu G; Wang Y; Wang L; Yao H; Wu X; Sun Y; Xu J
Eur J Med Chem; 2013 Jan; 59():322-8. PubMed ID: 23274570
[TBL] [Abstract][Full Text] [Related]
39. Oridonin inhibits BxPC-3 cell growth through cell apoptosis.
Xu B; Shen W; Liu X; Zhang T; Ren J; Fan Y; Xu J
Acta Biochim Biophys Sin (Shanghai); 2015 Mar; 47(3):164-73. PubMed ID: 25651847
[TBL] [Abstract][Full Text] [Related]
40. Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function.
Bi E; Liu D; Li Y; Mao X; Wang A; Wang J
Braz J Med Biol Res; 2018 Nov; 51(12):e7599. PubMed ID: 30462771
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
