These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
162 related articles for article (PubMed ID: 30982137)
1. Bioprocess development of a stable FUT8 Yuan Y; Zong H; Bai J; Han L; Wang L; Zhang X; Zhang X; Zhang J; Xu C; Zhu J; Zhang B Bioprocess Biosyst Eng; 2019 Aug; 42(8):1263-1271. PubMed ID: 30982137 [TBL] [Abstract][Full Text] [Related]
2. Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies. Malphettes L; Freyvert Y; Chang J; Liu PQ; Chan E; Miller JC; Zhou Z; Nguyen T; Tsai C; Snowden AW; Collingwood TN; Gregory PD; Cost GJ Biotechnol Bioeng; 2010 Aug; 106(5):774-83. PubMed ID: 20564614 [TBL] [Abstract][Full Text] [Related]
3. Producing defucosylated antibodies with enhanced in vitro antibody-dependent cellular cytotoxicity via Zong H; Han L; Ding K; Wang J; Sun T; Zhang X; Cagliero C; Jiang H; Xie Y; Xu J; Zhang B; Zhu J Eng Life Sci; 2017 Jul; 17(7):801-808. PubMed ID: 32624826 [TBL] [Abstract][Full Text] [Related]
4. Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity. Yamane-Ohnuki N; Kinoshita S; Inoue-Urakubo M; Kusunoki M; Iida S; Nakano R; Wakitani M; Niwa R; Sakurada M; Uchida K; Shitara K; Satoh M Biotechnol Bioeng; 2004 Sep; 87(5):614-22. PubMed ID: 15352059 [TBL] [Abstract][Full Text] [Related]
5. Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA. Mori K; Kuni-Kamochi R; Yamane-Ohnuki N; Wakitani M; Yamano K; Imai H; Kanda Y; Niwa R; Iida S; Uchida K; Shitara K; Satoh M Biotechnol Bioeng; 2004 Dec; 88(7):901-8. PubMed ID: 15515168 [TBL] [Abstract][Full Text] [Related]
6. A defucosylated anti-CD317 antibody exhibited enhanced antibody-dependent cellular cytotoxicity against primary myeloma cells in the presence of effectors from patients. Ishiguro T; Kawai S; Habu K; Sugimoto M; Shiraiwa H; Iijima S; Ozaki S; Matsumoto T; Yamada-Okabe H Cancer Sci; 2010 Oct; 101(10):2227-33. PubMed ID: 20701608 [TBL] [Abstract][Full Text] [Related]
7. Double knockdown of alpha1,6-fucosyltransferase (FUT8) and GDP-mannose 4,6-dehydratase (GMD) in antibody-producing cells: a new strategy for generating fully non-fucosylated therapeutic antibodies with enhanced ADCC. Imai-Nishiya H; Mori K; Inoue M; Wakitani M; Iida S; Shitara K; Satoh M BMC Biotechnol; 2007 Nov; 7():84. PubMed ID: 18047682 [TBL] [Abstract][Full Text] [Related]
8. Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies. Wong AW; Baginski TK; Reilly DE Biotechnol Bioeng; 2010 Aug; 106(5):751-63. PubMed ID: 20564613 [TBL] [Abstract][Full Text] [Related]
9. Comparison of cell lines for stable production of fucose-negative antibodies with enhanced ADCC. Kanda Y; Yamane-Ohnuki N; Sakai N; Yamano K; Nakano R; Inoue M; Misaka H; Iida S; Wakitani M; Konno Y; Yano K; Shitara K; Hosoi S; Satoh M Biotechnol Bioeng; 2006 Jul; 94(4):680-8. PubMed ID: 16609957 [TBL] [Abstract][Full Text] [Related]
10. Application of the CRISPR/Cas9 Gene Editing Method for Modulating Antibody Fucosylation in CHO Cells. Wang Q; Aliyu L; Chung CY; Rosenberg JN; Yu G; Betenbaugh MJ Methods Mol Biol; 2024; 2810():249-271. PubMed ID: 38926284 [TBL] [Abstract][Full Text] [Related]
11. Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: a new strategy for generating completely non-fucosylated recombinant therapeutics. Kanda Y; Imai-Nishiya H; Kuni-Kamochi R; Mori K; Inoue M; Kitajima-Miyama K; Okazaki A; Iida S; Shitara K; Satoh M J Biotechnol; 2007 Jun; 130(3):300-10. PubMed ID: 17559959 [TBL] [Abstract][Full Text] [Related]
12. Glycoproteomic Characterization of FUT8 Knock-Out CHO Cells Reveals Roles of FUT8 in the Glycosylation. Yang G; Wang Q; Chen L; Betenbaugh MJ; Zhang H Front Chem; 2021; 9():755238. PubMed ID: 34778211 [TBL] [Abstract][Full Text] [Related]
13. Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function. Beuger V; Künkele KP; Koll H; Gärtner A; Bähner M; Burtscher H; Klein C Biotechnol Appl Biochem; 2009 May; 53(Pt 1):31-7. PubMed ID: 19032154 [TBL] [Abstract][Full Text] [Related]
14. Fed-batch bioreactor performance and cell line stability evaluation of the artificial chromosome expression technology expressing an IgG1 in Chinese hamster ovary cells. Combs RG; Yu E; Roe S; Piatchek MB; Jones HL; Mott J; Kennard ML; Goosney DL; Monteith D Biotechnol Prog; 2011; 27(1):201-8. PubMed ID: 21312367 [TBL] [Abstract][Full Text] [Related]
15. Application of the CRISPR/Cas9 Gene Editing Method for Modulating Antibody Fucosylation in CHO Cells. Wang Q; Chung CY; Rosenberg JN; Yu G; Betenbaugh MJ Methods Mol Biol; 2018; 1850():237-257. PubMed ID: 30242691 [TBL] [Abstract][Full Text] [Related]
16. Glycoengineering of pertuzumab and its impact on the pharmacokinetic/pharmacodynamic properties. Luo C; Chen S; Xu N; Wang C; Sai WB; Zhao W; Li YC; Hu XJ; Tian H; Gao XD; Yao WB Sci Rep; 2017 Apr; 7():46347. PubMed ID: 28397880 [TBL] [Abstract][Full Text] [Related]
17. Differential gene expression of a feed-spiked super-producing CHO cell line. Reinhart D; Damjanovic L; Castan A; Ernst W; Kunert R J Biotechnol; 2018 Nov; 285():23-37. PubMed ID: 30157452 [TBL] [Abstract][Full Text] [Related]
18. FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality. Louie S; Haley B; Marshall B; Heidersbach A; Yim M; Brozynski M; Tang D; Lam C; Petryniak B; Shaw D; Shim J; Miller A; Lowe JB; Snedecor B; Misaghi S Biotechnol Bioeng; 2017 Mar; 114(3):632-644. PubMed ID: 27666939 [TBL] [Abstract][Full Text] [Related]
19. A high cell density transient transfection system for therapeutic protein expression based on a CHO GS-knockout cell line: process development and product quality assessment. Rajendra Y; Hougland MD; Alam R; Morehead TA; Barnard GC Biotechnol Bioeng; 2015 May; 112(5):977-86. PubMed ID: 25502369 [TBL] [Abstract][Full Text] [Related]
20. Benchmarking of commercially available CHO cell culture media for antibody production. Reinhart D; Damjanovic L; Kaisermayer C; Kunert R Appl Microbiol Biotechnol; 2015 Jun; 99(11):4645-57. PubMed ID: 25846330 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]