BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

515 related articles for article (PubMed ID: 30982602)

  • 1. A Compendium of Mutational Signatures of Environmental Agents.
    Kucab JE; Zou X; Morganella S; Joel M; Nanda AS; Nagy E; Gomez C; Degasperi A; Harris R; Jackson SP; Arlt VM; Phillips DH; Nik-Zainal S
    Cell; 2019 May; 177(4):821-836.e16. PubMed ID: 30982602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutational spectra and mutational signatures: Insights into cancer aetiology and mechanisms of DNA damage and repair.
    Phillips DH
    DNA Repair (Amst); 2018 Nov; 71():6-11. PubMed ID: 30236628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The topography of mutational processes in breast cancer genomes.
    Morganella S; Alexandrov LB; Glodzik D; Zou X; Davies H; Staaf J; Sieuwerts AM; Brinkman AB; Martin S; Ramakrishna M; Butler A; Kim HY; Borg Å; Sotiriou C; Futreal PA; Campbell PJ; Span PN; Van Laere S; Lakhani SR; Eyfjord JE; Thompson AM; Stunnenberg HG; van de Vijver MJ; Martens JW; Børresen-Dale AL; Richardson AL; Kong G; Thomas G; Sale J; Rada C; Stratton MR; Birney E; Nik-Zainal S
    Nat Commun; 2016 May; 7():11383. PubMed ID: 27136393
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network.
    Pei G; Hu R; Dai Y; Zhao Z; Jia P
    Oncogene; 2020 Jul; 39(27):5031-5041. PubMed ID: 32528130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns.
    Sørensen SG; Shrikhande A; Poulsgaard GA; Christensen MH; Bertl J; Laursen BE; Hoffmann ER; Pedersen JS
    Elife; 2023 Mar; 12():. PubMed ID: 36883553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.
    Drost J; van Boxtel R; Blokzijl F; Mizutani T; Sasaki N; Sasselli V; de Ligt J; Behjati S; Grolleman JE; van Wezel T; Nik-Zainal S; Kuiper RP; Cuppen E; Clevers H
    Science; 2017 Oct; 358(6360):234-238. PubMed ID: 28912133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A framework for mutational signature analysis based on DNA shape parameters.
    Karolak A; Levatić J; Supek F
    PLoS One; 2022; 17(1):e0262495. PubMed ID: 35015788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational signature SBS8 predominantly arises due to late replication errors in cancer.
    Singh VK; Rastogi A; Hu X; Wang Y; De S
    Commun Biol; 2020 Aug; 3(1):421. PubMed ID: 32747711
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two main mutational processes operate in the absence of DNA mismatch repair.
    Németh E; Lovrics A; Gervai JZ; Seki M; Rospo G; Bardelli A; Szüts D
    DNA Repair (Amst); 2020 May; 89():102827. PubMed ID: 32126497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.
    Petljak M; Alexandrov LB; Brammeld JS; Price S; Wedge DC; Grossmann S; Dawson KJ; Ju YS; Iorio F; Tubio JMC; Koh CC; Georgakopoulos-Soares I; Rodríguez-Martín B; Otlu B; O'Meara S; Butler AP; Menzies A; Bhosle SG; Raine K; Jones DR; Teague JW; Beal K; Latimer C; O'Neill L; Zamora J; Anderson E; Patel N; Maddison M; Ng BL; Graham J; Garnett MJ; McDermott U; Nik-Zainal S; Campbell PJ; Stratton MR
    Cell; 2019 Mar; 176(6):1282-1294.e20. PubMed ID: 30849372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substitution mutational signatures in whole-genome-sequenced cancers in the UK population.
    Degasperi A; Zou X; Amarante TD; Martinez-Martinez A; Koh GCC; Dias JML; Heskin L; Chmelova L; Rinaldi G; Wang VYW; Nanda AS; Bernstein A; Momen SE; Young J; Perez-Gil D; Memari Y; Badja C; Shooter S; Czarnecki J; Brown MA; Davies HR; ; Nik-Zainal S
    Science; 2022 Apr; 376(6591):. PubMed ID: 35949260
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Experimental investigations of carcinogen-induced mutation spectra: Innovation, challenges and future directions.
    Melki PN; Korenjak M; Zavadil J
    Mutat Res Genet Toxicol Environ Mutagen; 2020 May; 853():503195. PubMed ID: 32522347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of mutational signatures in C. elegans: Implications for cancer genome analysis.
    Meier B; Volkova NV; Gerstung M; Gartner A
    DNA Repair (Amst); 2020 Nov; 95():102957. PubMed ID: 32980770
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms underlying mutational signatures in human cancers.
    Helleday T; Eshtad S; Nik-Zainal S
    Nat Rev Genet; 2014 Sep; 15(9):585-98. PubMed ID: 24981601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.
    Haradhvala NJ; Polak P; Stojanov P; Covington KR; Shinbrot E; Hess JM; Rheinbay E; Kim J; Maruvka YE; Braunstein LZ; Kamburov A; Hanawalt PC; Wheeler DA; Koren A; Lawrence MS; Getz G
    Cell; 2016 Jan; 164(3):538-49. PubMed ID: 26806129
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The repertoire of mutational signatures in human cancer.
    Alexandrov LB; Kim J; Haradhvala NJ; Huang MN; Tian Ng AW; Wu Y; Boot A; Covington KR; Gordenin DA; Bergstrom EN; Islam SMA; Lopez-Bigas N; Klimczak LJ; McPherson JR; Morganella S; Sabarinathan R; Wheeler DA; Mustonen V; ; Getz G; Rozen SG; Stratton MR;
    Nature; 2020 Feb; 578(7793):94-101. PubMed ID: 32025018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Experimental systems for the analysis of mutational signatures: no 'one-size-fits-all' solution.
    Ivanov D; Hwang T; Sitko LK; Lee S; Gartner A
    Biochem Soc Trans; 2023 Jun; 51(3):1307-1317. PubMed ID: 37283472
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RepairSig: Deconvolution of DNA damage and repair contributions to the mutational landscape of cancer.
    Wojtowicz D; Hoinka J; Amgalan B; Kim YA; Przytycka TM
    Cell Syst; 2021 Oct; 12(10):994-1003.e4. PubMed ID: 34375586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational spectra are associated with bacterial niche.
    Ruis C; Weimann A; Tonkin-Hill G; Pandurangan AP; Matuszewska M; Murray GGR; Lévesque RC; Blundell TL; Floto RA; Parkhill J
    Nat Commun; 2023 Nov; 14(1):7091. PubMed ID: 37925514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy.
    Hatakeyama K; Nagashima T; Ohshima K; Ohnami S; Ohnami S; Shimoda Y; Serizawa M; Maruyama K; Naruoka A; Akiyama Y; Urakami K; Kusuhara M; Mochizuki T; Yamaguchi K
    Cancer Sci; 2019 Aug; 110(8):2620-2628. PubMed ID: 31152682
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.