BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 30982732)

  • 1. Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.
    Molinaro A; Becattini B; Mazzoli A; Bleve A; Radici L; Maxvall I; Sopasakis VR; Molinaro A; Bäckhed F; Solinas G
    Cell Metab; 2019 Jun; 29(6):1400-1409.e5. PubMed ID: 30982732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect.
    Becattini B; Molinaro A; Henricsson M; Borén J; Solinas G
    Cell Rep; 2024 May; 43(5):114132. PubMed ID: 38656871
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
    Liu TY; Shi CX; Gao R; Sun HJ; Xiong XQ; Ding L; Chen Q; Li YH; Wang JJ; Kang YM; Zhu GQ
    Clin Sci (Lond); 2015 Nov; 129(10):839-50. PubMed ID: 26201094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy.
    Ksionda O; Mues M; Wandler AM; Donker L; Tenhagen M; Jun J; Ducker GS; Matlawska-Wasowska K; Shannon K; Shokat KM; Roose JP
    PLoS One; 2018; 13(5):e0193849. PubMed ID: 29799846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3Kα and PI3Kγ.
    Martinez NG; Thieker DF; Carey LM; Rasquinha JA; Kistler SK; Kuhlman BA; Campbell SL
    J Mol Biol; 2021 Apr; 433(8):166838. PubMed ID: 33539876
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatidylinositol 3-kinase β and δ isoforms play key roles in metastasis of prostate cancer DU145 cells.
    Zhang Z; Liu J; Wang Y; Tan X; Zhao W; Xing X; Qiu Y; Wang R; Jin M; Fan G; Zhang P; Zhong Y; Kong D
    FASEB J; 2018 Nov; 32(11):5967-5975. PubMed ID: 29792732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Regulation of Lipid Deposition by Insulin in Goose Liver Cells Is Mediated by the PI3K-AKT-mTOR Signaling Pathway.
    Han C; Wei S; He F; Liu D; Wan H; Liu H; Li L; Xu H; Du X; Xu F
    PLoS One; 2015; 10(5):e0098759. PubMed ID: 25945932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN influences insulin and lipid metabolism in bovine hepatocytes in vitro.
    Deng Q; Ma D; Sun G; Yuan X; Wang Z; Liu G
    J Dairy Res; 2019 Feb; 86(1):73-76. PubMed ID: 30819264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. cAMP-GEF cytoprotection by Src tyrosine kinase activation of phosphoinositide-3-kinase p110 beta/alpha in rat hepatocytes.
    Gates A; Hohenester S; Anwer MS; Webster CR
    Am J Physiol Gastrointest Liver Physiol; 2009 Apr; 296(4):G764-74. PubMed ID: 19196950
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.
    Braccini L; Ciraolo E; Campa CC; Perino A; Longo DL; Tibolla G; Pregnolato M; Cao Y; Tassone B; Damilano F; Laffargue M; Calautti E; Falasca M; Norata GD; Backer JM; Hirsch E
    Nat Commun; 2015 Jun; 6():7400. PubMed ID: 26100075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer.
    Choi C; Kwon J; Lim S; Helfman DM
    Oncotarget; 2016 Sep; 7(39):63466-63487. PubMed ID: 27563827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dichloroacetate stimulates glycogen accumulation in primary hepatocytes through an insulin-independent mechanism.
    Lingohr MK; Bull RJ; Kato-Weinstein J; Thrall BD
    Toxicol Sci; 2002 Aug; 68(2):508-15. PubMed ID: 12151648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Better Understanding of Phosphoinositide 3-Kinase (PI3K) Pathways in Vasculature: Towards Precision Therapy Targeting Angiogenesis and Tumor Blood Supply.
    Tsvetkov D; Shymanets A; Huang Y; Bucher K; Piekorz R; Hirsch E; Beer-Hammer S; Harteneck C; Gollasch M; Nürnberg B
    Biochemistry (Mosc); 2016 Jul; 81(7):691-9. PubMed ID: 27449615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatidylinositol 3-kinase and Ras/mitogen-activated protein kinase signaling pathways are required for the regulation of 5-aminolevulinate synthase gene expression by insulin.
    Scassa ME; Guberman AS; Varone CL; Cánepa ET
    Exp Cell Res; 2001 Dec; 271(2):201-13. PubMed ID: 11716532
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.
    Schwartz S; Wongvipat J; Trigwell CB; Hancox U; Carver BS; Rodrik-Outmezguine V; Will M; Yellen P; de Stanchina E; Baselga J; Scher HI; Barry ST; Sawyers CL; Chandarlapaty S; Rosen N
    Cancer Cell; 2015 Jan; 27(1):109-22. PubMed ID: 25544636
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.
    McLean BA; Kienesberger PC; Wang W; Masson G; Zhabyeyev P; Dyck JR; Oudit GY
    J Mol Cell Cardiol; 2013 Jan; 54():9-18. PubMed ID: 23142539
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.
    McLean BA; Zhabyeyev P; Patel VB; Basu R; Parajuli N; DesAulniers J; Murray AG; Kassiri Z; Vanhaesebroeck B; Oudit GY
    Cardiovasc Res; 2015 Mar; 105(3):292-303. PubMed ID: 25618408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A pharmacological model reveals biased dependency on PI3K isoforms for tumor cell growth.
    Wang X; Li JP; Yang Y; Ding J; Meng LH
    Acta Pharmacol Sin; 2013 Sep; 34(9):1201-7. PubMed ID: 23892273
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survival.
    Juss JK; Hayhoe RP; Owen CE; Bruce I; Walmsley SR; Cowburn AS; Kulkarni S; Boyle KB; Stephens L; Hawkins PT; Chilvers ER; Condliffe AM
    PLoS One; 2012; 7(9):e45933. PubMed ID: 23029326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.
    Smith LD; Hickman ES; Parry RV; Westwick J; Ward SG
    Cell Signal; 2007 Dec; 19(12):2528-39. PubMed ID: 17900864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.