BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 30982732)

  • 21. Autocrine signaling through Ras regulates cell survival activity in human glioma cells: potential cross-talk between Ras and the phosphatidylinositol 3-kinase-Akt pathway.
    Sakata K; Kato S; Fox JC; Shigemori M; Morimatsu M
    J Neuropathol Exp Neurol; 2002 Nov; 61(11):975-83. PubMed ID: 12430714
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Insulin Stimulates Goose Liver Cell Growth by Activating PI3K-AKT-mTOR Signal Pathway.
    Han C; Wei S; Song Q; He F; Xiong X; Wan H; Liu D; Ye F; Liu H; Li L; Xu H; Du X; Kang B; Zeng X
    Cell Physiol Biochem; 2016; 38(2):558-70. PubMed ID: 26845041
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers.
    Nussinov R; Zhang M; Tsai CJ; Jang H
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun; 1864(6 Pt B):2304-2314. PubMed ID: 29097261
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity.
    Toulany M; Baumann M; Rodemann HP
    Mol Cancer Res; 2007 Aug; 5(8):863-72. PubMed ID: 17699110
    [TBL] [Abstract][Full Text] [Related]  

  • 25. [PI3K isoforms PI3Kβ and PI3Kδ play different roles in KIT mutation-mediated cell transformation].
    Zhang S; Zhu G; Shi J; Yang J; Jiang Z; Zhang L; Dou K; Sun J
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2021 Jan; 37(1):39-46. PubMed ID: 33441227
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition.
    Ning H; Sun Z; Liu Y; Liu L; Hao L; Ye Y; Feng R; Li J; Li Y; Chu X; Li S; Sun C
    Nutrients; 2016 Apr; 8(4):227. PubMed ID: 27104558
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK; Graab U; Fulda S
    Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion.
    Leibiger B; Moede T; Uhles S; Barker CJ; Creveaux M; Domin J; Berggren PO; Leibiger IB
    FASEB J; 2010 Jun; 24(6):1824-37. PubMed ID: 20061534
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Insulin signalling in hepatocytes of humans with type 2 diabetes: excessive production and activity of protein kinase C-ι (PKC-ι) and dependent processes and reversal by PKC-ι inhibitors.
    Sajan MP; Farese RV
    Diabetologia; 2012 May; 55(5):1446-57. PubMed ID: 22349071
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    Luo Y; Dixon CJ; Hall JF; White PJ; Boarder MR
    J Pharmacol Exp Ther; 2007 Jun; 321(3):884-91. PubMed ID: 17371807
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor.
    Nylander S; Kull B; Björkman JA; Ulvinge JC; Oakes N; Emanuelsson BM; Andersson M; Skärby T; Inghardt T; Fjellström O; Gustafsson D
    J Thromb Haemost; 2012 Oct; 10(10):2127-36. PubMed ID: 22906130
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
    Akutagawa J; Huang TQ; Epstein I; Chang T; Quirindongo-Crespo M; Cottonham CL; Dail M; Slusher BS; Friedman LS; Sampath D; Braun BS
    Leukemia; 2016 Jun; 30(6):1335-43. PubMed ID: 26965285
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.
    Clement E; Inuzuka H; Nihira NT; Wei W; Toker A
    Sci Signal; 2018 Mar; 11(521):. PubMed ID: 29535262
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
    Carnero A; Blanco-Aparicio C; Renner O; Link W; Leal JF
    Curr Cancer Drug Targets; 2008 May; 8(3):187-98. PubMed ID: 18473732
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN; Easton J; Huang S; Veverka KA; Germain GS; Harwood FC; Houghton PJ
    Cancer Res; 2003 Jan; 63(2):364-74. PubMed ID: 12543789
    [TBL] [Abstract][Full Text] [Related]  

  • 36. PTEN expression controls cellular response to cetuximab by mediating PI3K/AKT and RAS/RAF/MAPK downstream signaling in KRAS wild-type, hormone refractory prostate cancer cells.
    Bouali S; Chrétien AS; Ramacci C; Rouyer M; Becuwe P; Merlin JL
    Oncol Rep; 2009 Mar; 21(3):731-5. PubMed ID: 19212633
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer: Biological and therapeutic significance.
    Ediriweera MK; Tennekoon KH; Samarakoon SR
    Semin Cancer Biol; 2019 Dec; 59():147-160. PubMed ID: 31128298
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.
    Chen YW; Huang CF; Tsai KS; Yang RS; Yen CC; Yang CY; Lin-Shiau SY; Liu SH
    Diabetes; 2006 Jun; 55(6):1614-24. PubMed ID: 16731823
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeting the PI3K/AKT signaling pathway in anticancer research: a recent update on inhibitor design and clinical trials (2020-2023).
    Sabbah DA; Hajjo R; Bardaweel SK; Zhong HA
    Expert Opin Ther Pat; 2024 Mar; 34(3):141-158. PubMed ID: 38557273
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanisms of hepatocyte growth factor-mediated signaling in differentiation of pancreatic ductal epithelial cells into insulin-producing cells.
    Li XY; Zhan XR; Lu C; Liu XM; Wang XC
    Biochem Biophys Res Commun; 2010 Jul; 398(3):389-94. PubMed ID: 20599723
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.