These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 30984545)

  • 1. 1-Hydroxy-xanthine derivatives inhibit the human Caf1 nuclease and Caf1-containing nuclease complexes via Mg
    Airhihen B; Pavanello L; Jadhav GP; Fischer PM; Winkler GS
    FEBS Open Bio; 2019 Apr; 9(4):717-727. PubMed ID: 30984545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.
    Maryati M; Airhihen B; Winkler GS
    Biochem J; 2015 Jul; 469(1):169-76. PubMed ID: 25944446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of Substituted 5-(2-Hydroxybenzoyl)-2-Pyridone Analogues as Inhibitors of the Human Caf1/CNOT7 Ribonuclease.
    Kaur I; Jadhav GP; Fischer PM; Winkler GS
    Molecules; 2024 Sep; 29(18):. PubMed ID: 39339346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements.
    Zhang Q; Pavanello L; Potapov A; Bartlam M; Winkler GS
    Protein Sci; 2022 Mar; 31(3):758-764. PubMed ID: 34923703
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1.
    Jadhav GP; Kaur I; Maryati M; Airhihen B; Fischer PM; Winkler GS
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4219-24. PubMed ID: 26299350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex.
    Winkler GS; Balacco DL
    Front Genet; 2013 Dec; 4():296. PubMed ID: 24391663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.
    Chen Y; Khazina E; Izaurralde E; Weichenrieder O
    Nucleic Acids Res; 2021 Jun; 49(11):6489-6510. PubMed ID: 34038562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The central region of CNOT1 and CNOT9 stimulates deadenylation by the Ccr4-Not nuclease module.
    Pavanello L; Hall B; Airhihen B; Winkler GS
    Biochem J; 2018 Nov; 475(21):3437-3450. PubMed ID: 30309886
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.
    Petit AP; Wohlbold L; Bawankar P; Huntzinger E; Schmidt S; Izaurralde E; Weichenrieder O
    Nucleic Acids Res; 2012 Nov; 40(21):11058-72. PubMed ID: 22977175
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction.
    Basquin J; Roudko VV; Rode M; Basquin C; Séraphin B; Conti E
    Mol Cell; 2012 Oct; 48(2):207-18. PubMed ID: 22959269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.
    Maryati M; Kaur I; Jadhav GP; Olotu-Umoren L; Oveh B; Hashmi L; Fischer PM; Winkler GS
    Nucleic Acids Res; 2014 Mar; 42(5):e30. PubMed ID: 24170810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.
    Piao X; Zhang X; Wu L; Belasco JG
    Mol Cell Biol; 2010 Mar; 30(6):1486-94. PubMed ID: 20065043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases.
    Webster MW; Chen YH; Stowell JAW; Alhusaini N; Sweet T; Graveley BR; Coller J; Passmore LA
    Mol Cell; 2018 Jun; 70(6):1089-1100.e8. PubMed ID: 29932902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4.
    Ohn T; Chiang YC; Lee DJ; Yao G; Zhang C; Denis CL
    Nucleic Acids Res; 2007; 35(9):3002-15. PubMed ID: 17439972
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for inhibition of the deadenylase activity of human CNOT6L.
    Zhang Q; Yan D; Guo E; Ding B; Yang W; Liu R; Yamamoto T; Bartlam M
    FEBS Lett; 2016 Apr; 590(8):1270-9. PubMed ID: 27013054
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila.
    Temme C; Zaessinger S; Meyer S; Simonelig M; Wahle E
    EMBO J; 2004 Jul; 23(14):2862-71. PubMed ID: 15215893
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex.
    Doidge R; Mittal S; Aslam A; Winkler GS
    Biochem Soc Trans; 2012 Aug; 40(4):896-901. PubMed ID: 22817755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.
    Aslam A; Mittal S; Koch F; Andrau JC; Winkler GS
    Mol Biol Cell; 2009 Sep; 20(17):3840-50. PubMed ID: 19605561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity.
    Clark LB; Viswanathan P; Quigley G; Chiang YC; McMahon JS; Yao G; Chen J; Nelsbach A; Denis CL
    J Biol Chem; 2004 Apr; 279(14):13616-23. PubMed ID: 14734555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay.
    Yi H; Park J; Ha M; Lim J; Chang H; Kim VN
    Mol Cell; 2018 Jun; 70(6):1081-1088.e5. PubMed ID: 29932901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.