BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 30987979)

  • 1. Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1
    Shah R; Singh SJ; Eddy K; Filipp FV; Chen S
    Cancer Res; 2019 Apr; 79(8):1799-1809. PubMed ID: 30987979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.
    Namkoong J; Shin SS; Lee HJ; Marín YE; Wall BA; Goydos JS; Chen S
    Cancer Res; 2007 Mar; 67(5):2298-305. PubMed ID: 17332361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutamatergic pathway targeting in melanoma: single-agent and combinatorial therapies.
    Lee HJ; Wall BA; Wangari-Talbot J; Shin SS; Rosenberg S; Chan JL; Namkoong J; Goydos JS; Chen S
    Clin Cancer Res; 2011 Nov; 17(22):7080-92. PubMed ID: 21844014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The glutamate release inhibitor Riluzole decreases migration, invasion, and proliferation of melanoma cells.
    Le MN; Chan JL; Rosenberg SA; Nabatian AS; Merrigan KT; Cohen-Solal KA; Goydos JS
    J Invest Dermatol; 2010 Sep; 130(9):2240-9. PubMed ID: 20505744
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.
    Wall BA; Wangari-Talbot J; Shin SS; Schiff D; Sierra J; Yu LJ; Khan A; Haffty B; Goydos JS; Chen S
    Pigment Cell Melanoma Res; 2014 Mar; 27(2):263-74. PubMed ID: 24330389
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
    Martino JJ; Wall BA; Mastrantoni E; Wilimczyk BJ; La Cava SN; Degenhardt K; White E; Chen S
    Oncogene; 2013 Sep; 32(37):4366-76. PubMed ID: 23085756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.
    Wen Y; Li J; Koo J; Shin SS; Lin Y; Jeong BS; Mehnert JM; Chen S; Cohen-Sola KA; Goydos JS
    Cancer Res; 2014 May; 74(9):2499-509. PubMed ID: 24491800
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional effects of GRM1 suppression in human melanoma cells.
    Wangari-Talbot J; Wall BA; Goydos JS; Chen S
    Mol Cancer Res; 2012 Nov; 10(11):1440-50. PubMed ID: 22798429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.
    Teh JL; Shah R; La Cava S; Dolfi SC; Mehta MS; Kongara S; Price S; Ganesan S; Reuhl KR; Hirshfield KM; Karantza V; Chen S
    Breast Cancer Res Treat; 2015 May; 151(1):57-73. PubMed ID: 25859923
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic Signaling Cascades Prompted by Glutaminolysis in Cancer.
    Shah R; Chen S
    Cancers (Basel); 2020 Sep; 12(9):. PubMed ID: 32937954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.
    Speyer CL; Nassar MA; Hachem AH; Bukhsh MA; Jafry WS; Khansa RM; Gorski DH
    Breast Cancer Res Treat; 2016 Jun; 157(2):217-228. PubMed ID: 27146584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Riluzole enhances ionizing radiation-induced cytotoxicity in human melanoma cells that ectopically express metabotropic glutamate receptor 1 in vitro and in vivo.
    Khan AJ; Wall B; Ahlawat S; Green C; Schiff D; Mehnert JM; Goydos JS; Chen S; Haffty BG
    Clin Cancer Res; 2011 Apr; 17(7):1807-14. PubMed ID: 21325066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The glutaminase inhibitor telaglenastat enhances the antitumor activity of signal transduction inhibitors everolimus and cabozantinib in models of renal cell carcinoma.
    Emberley E; Pan A; Chen J; Dang R; Gross M; Huang T; Li W; MacKinnon A; Singh D; Sotirovska N; Steggerda SM; Wang T; Parlati F
    PLoS One; 2021; 16(11):e0259241. PubMed ID: 34731180
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
    Gross MI; Demo SD; Dennison JB; Chen L; Chernov-Rogan T; Goyal B; Janes JR; Laidig GJ; Lewis ER; Li J; Mackinnon AL; Parlati F; Rodriguez ML; Shwonek PJ; Sjogren EB; Stanton TF; Wang T; Yang J; Zhao F; Bennett MK
    Mol Cancer Ther; 2014 Apr; 13(4):890-901. PubMed ID: 24523301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma.
    Abushahba W; Olabisi OO; Jeong BS; Boregowda RK; Wen Y; Liu F; Goydos JS; Lasfar A; Cohen-Solal KA
    PLoS One; 2012; 7(10):e47312. PubMed ID: 23077590
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
    Matre P; Velez J; Jacamo R; Qi Y; Su X; Cai T; Chan SM; Lodi A; Sweeney SR; Ma H; Davis RE; Baran N; Haferlach T; Su X; Flores ER; Gonzalez D; Konoplev S; Samudio I; DiNardo C; Majeti R; Schimmer AD; Li W; Wang T; Tiziani S; Konopleva M
    Oncotarget; 2016 Nov; 7(48):79722-79735. PubMed ID: 27806325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation.
    Shin SS; Namkoong J; Wall BA; Gleason R; Lee HJ; Chen S
    Pigment Cell Melanoma Res; 2008 Jun; 21(3):368-78. PubMed ID: 18435704
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon.
    Marín YE; Namkoong J; Cohen-Solal K; Shin SS; Martino JJ; Oka M; Chen S
    Cell Signal; 2006 Aug; 18(8):1279-86. PubMed ID: 16305822
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer.
    Singleton DC; Dechaume AL; Murray PM; Katt WP; Baguley BC; Leung EY
    BMC Cancer; 2020 May; 20(1):470. PubMed ID: 32450839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma.
    Mehnert JM; Silk AW; Lee JH; Dudek L; Jeong BS; Li J; Schenkel JM; Sadimin E; Kane M; Lin H; Shih WJ; Zloza A; Chen S; Goydos JS
    Pigment Cell Melanoma Res; 2018 Jul; 31(4):534-540. PubMed ID: 29453787
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.