BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 30988001)

  • 1. Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.
    Gingras AR; Lagarrigue F; Cuevas MN; Valadez AJ; Zorovich M; McLaughlin W; Lopez-Ramirez MA; Seban N; Ley K; Kiosses WB; Ginsberg MH
    J Cell Biol; 2019 Jun; 218(6):1799-1809. PubMed ID: 30988001
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rap1 and membrane lipids cooperatively recruit talin to trigger integrin activation.
    Bromberger T; Zhu L; Klapproth S; Qin J; Moser M
    J Cell Sci; 2019 Nov; 132(21):. PubMed ID: 31578239
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4
    Lagarrigue F; Tan B; Du Q; Fan Z; Lopez-Ramirez MA; Gingras AR; Wang H; Qi W; Sun H
    J Immunol; 2022 Mar; 208(6):1378-1388. PubMed ID: 35197328
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.
    Lee HS; Lim CJ; Puzon-McLaughlin W; Shattil SJ; Ginsberg MH
    J Biol Chem; 2009 Feb; 284(8):5119-27. PubMed ID: 19098287
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Talin-1 is the principal platelet Rap1 effector of integrin activation.
    Lagarrigue F; Paul DS; Gingras AR; Valadez AJ; Sun H; Lin J; Cuevas MN; Ablack JN; Lopez-Ramirez MA; Bergmeier W; Ginsberg MH
    Blood; 2020 Sep; 136(10):1180-1190. PubMed ID: 32518959
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two modes of integrin activation form a binary molecular switch in adhesion maturation.
    Lee HS; Anekal P; Lim CJ; Liu CC; Ginsberg MH
    Mol Biol Cell; 2013 May; 24(9):1354-62. PubMed ID: 23468527
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.
    Lagarrigue F; Gingras AR; Paul DS; Valadez AJ; Cuevas MN; Sun H; Lopez-Ramirez MA; Goult BT; Shattil SJ; Bergmeier W; Ginsberg MH
    Blood Adv; 2018 Sep; 2(18):2358-2368. PubMed ID: 30242097
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.
    Moes M; Rodius S; Coleman SJ; Monkley SJ; Goormaghtigh E; Tremuth L; Kox C; van der Holst PP; Critchley DR; Kieffer N
    J Biol Chem; 2007 Jun; 282(23):17280-8. PubMed ID: 17430904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.
    Liao Z; Gingras AR; Lagarrigue F; Ginsberg MH; Shattil SJ
    J Biol Chem; 2021; 296():100675. PubMed ID: 33865854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling.
    Chang YC; Zhang H; Franco-Barraza J; Brennan ML; Patel T; Cukierman E; Wu J
    Structure; 2014 Dec; 22(12):1810-1820. PubMed ID: 25465129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Rap1-RIAM-talin axis of integrin activation and blood cell function.
    Lagarrigue F; Kim C; Ginsberg MH
    Blood; 2016 Jul; 128(4):479-87. PubMed ID: 27207789
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
    Goult BT; Bouaouina M; Elliott PR; Bate N; Patel B; Gingras AR; Grossmann JG; Roberts GC; Calderwood DA; Critchley DR; Barsukov IL
    EMBO J; 2010 Mar; 29(6):1069-80. PubMed ID: 20150896
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice.
    Bromberger T; Klapproth S; Rohwedder I; Zhu L; Mittmann L; Reichel CA; Sperandio M; Qin J; Moser M
    Blood; 2018 Dec; 132(26):2754-2762. PubMed ID: 30442677
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.
    Han J; Lim CJ; Watanabe N; Soriani A; Ratnikov B; Calderwood DA; Puzon-McLaughlin W; Lafuente EM; Boussiotis VA; Shattil SJ; Ginsberg MH
    Curr Biol; 2006 Sep; 16(18):1796-806. PubMed ID: 16979556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The molecular basis of talin2's high affinity toward β1-integrin.
    Yuan Y; Li L; Zhu Y; Qi L; Azizi L; Hytönen VP; Zhan CG; Huang C
    Sci Rep; 2017 Feb; 7():41989. PubMed ID: 28155884
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.
    Kopp PM; Bate N; Hansen TM; Brindle NP; Praekelt U; Debrand E; Coleman S; Mazzeo D; Goult BT; Gingras AR; Pritchard CA; Critchley DR; Monkley SJ
    Eur J Cell Biol; 2010 Sep; 89(9):661-73. PubMed ID: 20605055
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding of Rap1 and Riam to Talin1 Fine-Tune β2 Integrin Activity During Leukocyte Trafficking.
    Bromberger T; Klapproth S; Rohwedder I; Weber J; Pick R; Mittmann L; Min-Weißenhorn SJ; Reichel CA; Scheiermann C; Sperandio M; Moser M
    Front Immunol; 2021; 12():702345. PubMed ID: 34489950
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
    Yang J; Zhu L; Zhang H; Hirbawi J; Fukuda K; Dwivedi P; Liu J; Byzova T; Plow EF; Wu J; Qin J
    Nat Commun; 2014 Dec; 5():5880. PubMed ID: 25520155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Direct binding of Talin to Rap1 is required for cell-ECM adhesion in
    Camp D; Haage A; Solianova V; Castle WM; Xu QA; Lostchuck E; Goult BT; Tanentzapf G
    J Cell Sci; 2018 Dec; 131(24):. PubMed ID: 30446511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.
    Stefanini L; Ye F; Snider AK; Sarabakhsh K; Piatt R; Paul DS; Bergmeier W; Petrich BG
    Blood; 2014 Apr; 123(17):2722-31. PubMed ID: 24585775
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.