BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 30988134)

  • 1. Genetic and pharmacological inhibition of acid ceramidase prevents asymmetric cell division by neosis.
    White-Gilbertson S; Lu P; Norris JS; Voelkel-Johnson C
    J Lipid Res; 2019 Jul; 60(7):1225-1235. PubMed ID: 30988134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tamoxifen is a candidate first-in-class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells-Unrecognized players in tumorigenesis.
    White-Gilbertson S; Lu P; Jones CM; Chiodini S; Hurley D; Das A; Delaney JR; Norris JS; Voelkel-Johnson C
    Cancer Med; 2020 May; 9(9):3142-3152. PubMed ID: 32135040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acid Ceramidase Depletion Impairs Neuronal Survival and Induces Morphological Defects in Neurites Associated with Altered Gene Transcription and Sphingolipid Content.
    Kyriakou K; Lederer CW; Kleanthous M; Drousiotou A; Malekkou A
    Int J Mol Sci; 2020 Feb; 21(5):. PubMed ID: 32111095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
    Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
    J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting acid ceramidase sensitises head and neck cancer to cisplatin.
    Roh JL; Park JY; Kim EH; Jang HJ
    Eur J Cancer; 2016 Jan; 52():163-72. PubMed ID: 26687835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acid ceramidase as a therapeutic target in metastatic prostate cancer.
    Camacho L; Meca-Cortés O; Abad JL; García S; Rubio N; Díaz A; Celià-Terrassa T; Cingolani F; Bermudo R; Fernández PL; Blanco J; Delgado A; Casas J; Fabriàs G; Thomson TM
    J Lipid Res; 2013 May; 54(5):1207-20. PubMed ID: 23423838
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression.
    Lucki NC; Bandyopadhyay S; Wang E; Merrill AH; Sewer MB
    Mol Endocrinol; 2012 Feb; 26(2):228-43. PubMed ID: 22261821
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production.
    Malvi P; Janostiak R; Nagarajan A; Zhang X; Wajapeyee N
    Mol Metab; 2021 Jun; 48():101217. PubMed ID: 33766731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling.
    Hawkins CC; Jones AB; Gordon ER; Williford SE; Harsh Y; Ziebro JK; Landis CJ; Gc S; Crossman DK; Cooper SJ; Ramanadham S; Doan N; Hjelmeland AB
    Cells; 2022 Jun; 11(12):. PubMed ID: 35741006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression.
    Lucki NC; Sewer MB
    J Biol Chem; 2011 Jun; 286(22):19399-409. PubMed ID: 21493710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs).
    Bowers RR; Andrade MF; Jones CM; White-Gilbertson S; Voelkel-Johnson C; Delaney JR
    BMC Cancer; 2022 Apr; 22(1):410. PubMed ID: 35421971
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibition.
    Ramírez de Molina A; de la Cueva A; Machado-Pinilla R; Rodriguez-Fanjul V; Gomez del Pulgar T; Cebrian A; Perona R; Lacal JC
    Curr Cancer Drug Targets; 2012 Jul; 12(6):617-24. PubMed ID: 22515519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acid Ceramidase: A Novel Therapeutic Target in Cancer.
    Vijayan Y; Lankadasari MB; Harikumar KB
    Curr Top Med Chem; 2019; 19(17):1512-1520. PubMed ID: 30827244
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ceramide Synthase 6 Maximizes p53 Function to Prevent Progeny Formation from Polyploid Giant Cancer Cells.
    Lu P; White-Gilbertson S; Beeson G; Beeson C; Ogretmen B; Norris J; Voelkel-Johnson C
    Cancers (Basel); 2021 May; 13(9):. PubMed ID: 34062962
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division.
    White-Gilbertson S; Lu P; Esobi I; Echesabal-Chen J; Mulholland PJ; Gooz M; Ogretmen B; Stamatikos A; Voelkel-Johnson C
    Sci Rep; 2022 May; 12(1):8971. PubMed ID: 35624221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and β1 integrin/FAK-mediated signalling.
    Klobučar M; Grbčić P; Pavelić SK; Jonjić N; Visentin S; Sedić M
    Biochem Biophys Res Commun; 2018 Sep; 503(2):843-848. PubMed ID: 29920241
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acid ceramidase promotes senescent cell survival.
    Munk R; Anerillas C; Rossi M; Tsitsipatis D; Martindale JL; Herman AB; Yang JH; Roberts JA; Varma VR; Pandey PR; Thambisetty M; Gorospe M; Abdelmohsen K
    Aging (Albany NY); 2021 Jun; 13(12):15750-15769. PubMed ID: 34102611
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse.
    Cheng JC; Bai A; Beckham TH; Marrison ST; Yount CL; Young K; Lu P; Bartlett AM; Wu BX; Keane BJ; Armeson KE; Marshall DT; Keane TE; Smith MT; Jones EE; Drake RR; Bielawska A; Norris JS; Liu X
    J Clin Invest; 2013 Oct; 123(10):4344-58. PubMed ID: 24091326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION.
    Realini N; Palese F; Pizzirani D; Pontis S; Basit A; Bach A; Ganesan A; Piomelli D
    J Biol Chem; 2016 Jan; 291(5):2422-34. PubMed ID: 26553872
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
    Morad SA; Messner MC; Levin JC; Abdelmageed N; Park H; Merrill AH; Cabot MC
    Cancer Chemother Pharmacol; 2013 Mar; 71(3):635-45. PubMed ID: 23263160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.