239 related articles for article (PubMed ID: 30988374)
1. Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes.
Cooke M; Casado-Medrano V; Ann J; Lee J; Blumberg PM; Abba MC; Kazanietz MG
Sci Rep; 2019 Apr; 9(1):6041. PubMed ID: 30988374
[TBL] [Abstract][Full Text] [Related]
2. Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes.
Cooke M; Zhou X; Casado-Medrano V; Lopez-Haber C; Baker MJ; Garg R; Ann J; Lee J; Blumberg PM; Kazanietz MG
J Biol Chem; 2018 Jun; 293(22):8330-8341. PubMed ID: 29636415
[TBL] [Abstract][Full Text] [Related]
3. Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.
Garcia-Bermejo ML; Leskow FC; Fujii T; Wang Q; Blumberg PM; Ohba M; Kuroki T; Han KC; Lee J; Marquez VE; Kazanietz MG
J Biol Chem; 2002 Jan; 277(1):645-55. PubMed ID: 11584014
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of membrane lipid-independent protein kinase Calpha activity by phorbol esters, diacylglycerols, and bryostatin-1.
Slater SJ; Taddeo FJ; Mazurek A; Stagliano BA; Milano SK; Kelly MB; Ho C; Stubbs CD
J Biol Chem; 1998 Sep; 273(36):23160-8. PubMed ID: 9722545
[TBL] [Abstract][Full Text] [Related]
5. Pharmacology of the receptors for the phorbol ester tumor promoters: multiple receptors with different biochemical properties.
Kazanietz MG; Caloca MJ; Eroles P; Fujii T; García-Bermejo ML; Reilly M; Wang H
Biochem Pharmacol; 2000 Nov; 60(10):1417-24. PubMed ID: 11020443
[TBL] [Abstract][Full Text] [Related]
6. Differential regulation of gene expression by protein kinase C isozymes as determined by genome-wide expression analysis.
Caino MC; von Burstin VA; Lopez-Haber C; Kazanietz MG
J Biol Chem; 2011 Apr; 286(13):11254-64. PubMed ID: 21252239
[TBL] [Abstract][Full Text] [Related]
7. Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C.
Holden NS; Squires PE; Kaur M; Bland R; Jones CE; Newton R
Cell Signal; 2008 Jul; 20(7):1338-48. PubMed ID: 18436431
[TBL] [Abstract][Full Text] [Related]
8. Design, Synthesis, and Characterization of Novel
Elhalem E; Bellomo A; Cooke M; Scravaglieri A; Pearce LV; Peach ML; Gandolfi Donadío L; Kazanietz MG; Comin MJ
J Med Chem; 2021 Aug; 64(15):11418-11431. PubMed ID: 34279947
[TBL] [Abstract][Full Text] [Related]
9. Bryostatin 1 inhibits phorbol ester-induced apoptosis in prostate cancer cells by differentially modulating protein kinase C (PKC) delta translocation and preventing PKCdelta-mediated release of tumor necrosis factor-alpha.
von Burstin VA; Xiao L; Kazanietz MG
Mol Pharmacol; 2010 Sep; 78(3):325-32. PubMed ID: 20516369
[TBL] [Abstract][Full Text] [Related]
10. Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains.
Ananthanarayanan B; Stahelin RV; Digman MA; Cho W
J Biol Chem; 2003 Nov; 278(47):46886-94. PubMed ID: 12954613
[TBL] [Abstract][Full Text] [Related]
11. A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.
Pu Y; Perry NA; Yang D; Lewin NE; Kedei N; Braun DC; Choi SH; Blumberg PM; Garfield SH; Stone JC; Duan D; Marquez VE
J Biol Chem; 2005 Jul; 280(29):27329-38. PubMed ID: 15923197
[TBL] [Abstract][Full Text] [Related]
12. Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway.
Yin L; Bennani-Baiti N; Powell CT
J Biol Chem; 2005 Feb; 280(7):5533-41. PubMed ID: 15611126
[TBL] [Abstract][Full Text] [Related]
13. Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase.
Dobkin-Bekman M; Rahamin-Ben Navi L; Shterntal B; Sviridonov L; Przedecki F; Naidich-Exler M; Brodie C; Seger R; Naor Z
Endocrinology; 2010 Oct; 151(10):4894-907. PubMed ID: 20810567
[TBL] [Abstract][Full Text] [Related]
14. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family.
Chen J; Deng F; Li J; Wang QJ
Biochem J; 2008 Apr; 411(2):333-42. PubMed ID: 18076381
[TBL] [Abstract][Full Text] [Related]
15. Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?
Nacro K; Bienfait B; Lee J; Han KC; Kang JH; Benzaria S; Lewin NE; Bhattacharyya DK; Blumberg PM; Marquez VE
J Med Chem; 2000 Mar; 43(5):921-44. PubMed ID: 10715158
[TBL] [Abstract][Full Text] [Related]
16. Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: mechanistic differences between protein kinases Cdelta and Cepsilon.
Stahelin RV; Digman MA; Medkova M; Ananthanarayanan B; Melowic HR; Rafter JD; Cho W
J Biol Chem; 2005 May; 280(20):19784-93. PubMed ID: 15769752
[TBL] [Abstract][Full Text] [Related]
17. Activation of Munc13-1 by Diacylglycerol (DAG)-Lactones.
Das J; You Y; Mathukumalli K; Ann J; Lee J; Marquez VE
Biochemistry; 2023 Sep; 62(18):2717-2726. PubMed ID: 37651159
[TBL] [Abstract][Full Text] [Related]
18. Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms.
Pu Y; Peach ML; Garfield SH; Wincovitch S; Marquez VE; Blumberg PM
J Biol Chem; 2006 Nov; 281(44):33773-88. PubMed ID: 16950780
[TBL] [Abstract][Full Text] [Related]
19. Involvement of multiple protein kinase C isozymes in the ACTH secretory pathway of AtT-20 cells.
McFerran BW; MacEwan DJ; Guild SB
Br J Pharmacol; 1995 May; 115(2):307-15. PubMed ID: 7670732
[TBL] [Abstract][Full Text] [Related]
20. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta.
Stahelin RV; Digman MA; Medkova M; Ananthanarayanan B; Rafter JD; Melowic HR; Cho W
J Biol Chem; 2004 Jul; 279(28):29501-12. PubMed ID: 15105418
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]