BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 30993888)

  • 1. SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.
    Xu L; Li Y; Zhou L; Dorfman RG; Liu L; Cai R; Jiang C; Tang D; Wang Y; Zou X; Wang L; Zhang M
    Cancer Med; 2019 May; 8(5):2380-2391. PubMed ID: 30993888
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The SIRT2/cMYC Pathway Inhibits Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming.
    Xu L; Wang L; Zhou L; Dorfman RG; Pan Y; Tang D; Wang Y; Yin Y; Jiang C; Zou X; Wu J; Zhang M
    Neoplasia; 2019 May; 21(5):429-441. PubMed ID: 30933885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.
    Finley LW; Carracedo A; Lee J; Souza A; Egia A; Zhang J; Teruya-Feldstein J; Moreira PI; Cardoso SM; Clish CB; Pandolfi PP; Haigis MC
    Cancer Cell; 2011 Mar; 19(3):416-28. PubMed ID: 21397863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
    Fan J; Shan C; Kang HB; Elf S; Xie J; Tucker M; Gu TL; Aguiar M; Lonning S; Chen H; Mohammadi M; Britton LM; Garcia BA; Alečković M; Kang Y; Kaluz S; Devi N; Van Meir EG; Hitosugi T; Seo JH; Lonial S; Gaddh M; Arellano M; Khoury HJ; Khuri FR; Boggon TJ; Kang S; Chen J
    Mol Cell; 2014 Feb; 53(4):534-48. PubMed ID: 24486017
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity.
    Kwak CH; Jin L; Han JH; Han CW; Kim E; Cho M; Chung TW; Bae SJ; Jang SB; Ha KT
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.
    Dan Li ; Wang C; Ma P; Yu Q; Gu M; Dong L; Jiang W; Pan S; Xie C; Han J; Lan Y; Sun J; Sheng P; Liu K; Wu Y; Liu L; Ma Y; Jiang H
    Cell Death Dis; 2018 May; 9(5):466. PubMed ID: 29700317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis.
    Zhang M; Pan Y; Tang D; Dorfman RG; Xu L; Zhou Q; Zhou L; Wang Y; Li Y; Yin Y; Kong B; Friess H; Zhao S; Wu JL; Wang L; Zou X
    Cell Commun Signal; 2019 Mar; 17(1):23. PubMed ID: 30866966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.
    Ozden O; Park SH; Wagner BA; Song HY; Zhu Y; Vassilopoulos A; Jung B; Buettner GR; Gius D
    Free Radic Biol Med; 2014 Nov; 76():163-172. PubMed ID: 25152236
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
    Liu F; Zhang W; You X; Liu Y; Li Y; Wang Z; Wang Y; Zhang X; Ye L
    Oncotarget; 2015 Sep; 6(29):27199-213. PubMed ID: 26309161
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization.
    Wei L; Zhou Y; Qiao C; Ni T; Li Z; You Q; Guo Q; Lu N
    Cell Death Dis; 2015 Apr; 6(4):e1714. PubMed ID: 25855962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.
    Wei (魏彤) T; Gao (高晶) J; Huang (黄程淋) C; Song (宋蓓) B; Sun (孙孟炜) M; Shen (沈伟利) W
    Arterioscler Thromb Vasc Biol; 2021 Feb; 41(2):714-730. PubMed ID: 33327751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of Pyruvate Dehydrogenase E1α Subunit Inhibits Warburg Effect and Induces Cell Apoptosis Through Mitochondria-Mediated Pathway in Hepatocellular Carcinoma.
    Sun J; Li J; Guo Z; Sun L; Juan C; Zhou Y; Gu H; Yu Y; Hu Q; Kan Q; Yu Z
    Oncol Res; 2019 Mar; 27(4):407-414. PubMed ID: 29444744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis.
    Haigis MC; Deng CX; Finley LW; Kim HS; Gius D
    Cancer Res; 2012 May; 72(10):2468-72. PubMed ID: 22589271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia.
    Peng F; Wang JH; Fan WJ; Meng YT; Li MM; Li TT; Cui B; Wang HF; Zhao Y; An F; Guo T; Liu XF; Zhang L; Lv L; Lv DK; Xu LZ; Xie JJ; Lin WX; Lam EW; Xu J; Liu Q
    Oncogene; 2018 Feb; 37(8):1062-1074. PubMed ID: 29106390
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endothelial Sirtuin 3 Dictates Glucose Transport to Cardiomyocyte and Sensitizes Pressure Overload-Induced Heart Failure.
    Zeng H; He X; Chen JX
    J Am Heart Assoc; 2020 Jun; 9(11):e015895. PubMed ID: 32468895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1α mediated signal pathway.
    Wang L; Yu Z; Ren S; Song J; Wang J; Du G
    Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2281-2292. PubMed ID: 30036603
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Forced overexpression of FBP1 inhibits proliferation and metastasis in cholangiocarcinoma cells via Wnt/β-catenin pathway.
    Zhao W; Yang S; Chen J; Zhao J; Dong J
    Life Sci; 2018 Oct; 210():224-234. PubMed ID: 30193944
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.
    Bell EL; Emerling BM; Ricoult SJ; Guarente L
    Oncogene; 2011 Jun; 30(26):2986-96. PubMed ID: 21358671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SIRT3 controls cancer metabolic reprogramming by regulating ROS and HIF.
    Schumacker PT
    Cancer Cell; 2011 Mar; 19(3):299-300. PubMed ID: 21397853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted Modulation of FAK/PI3K/PDK1/AKT and FAK/p53 Pathways by Cucurbitacin B for the Antiproliferation Effect Against Human Cholangiocarcinoma Cells.
    Klungsaeng S; Kukongviriyapan V; Prawan A; Kongpetch S; Senggunprai L
    Am J Chin Med; 2020; 48(6):1475-1489. PubMed ID: 32907364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.