BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

353 related articles for article (PubMed ID: 30997017)

  • 1. Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment.
    Kobets T; Iatropoulos MJ; Williams GM
    Toxicol Res (Camb); 2019 Mar; 8(2):123-145. PubMed ID: 30997017
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical carcinogen mechanisms of action and implications for testing methodology.
    Williams GM; Iatropoulos MJ; Weisburger JH
    Exp Toxicol Pathol; 1996 Feb; 48(2-3):101-11. PubMed ID: 8672863
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Review of the evidence for thresholds for DNA-Reactive and epigenetic experimental chemical carcinogens.
    Kobets T; Williams GM
    Chem Biol Interact; 2019 Mar; 301():88-111. PubMed ID: 30763546
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Guidelines for the evaluation of chemicals for carcinogenicity. Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment.
    Rep Health Soc Subj (Lond); 1991; 42():1-80. PubMed ID: 1763238
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?
    Gaylor DW
    Regul Toxicol Pharmacol; 2005 Mar; 41(2):128-33. PubMed ID: 15698536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk.
    Kobets T; Smith BPC; Williams GM
    Foods; 2022 Sep; 11(18):. PubMed ID: 36140952
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro.
    Parfett CL; Desaulniers D
    Int J Mol Sci; 2017 Jun; 18(6):. PubMed ID: 28587163
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carcinogenicity categorization of chemicals-new aspects to be considered in a European perspective.
    Bolt HM; Foth H; Hengstler JG; Degen GH
    Toxicol Lett; 2004 Jun; 151(1):29-41. PubMed ID: 15177638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
    Kirkland D; Pfuhler S; Tweats D; Aardema M; Corvi R; Darroudi F; Elhajouji A; Glatt H; Hastwell P; Hayashi M; Kasper P; Kirchner S; Lynch A; Marzin D; Maurici D; Meunier JR; Müller L; Nohynek G; Parry J; Parry E; Thybaud V; Tice R; van Benthem J; Vanparys P; White P
    Mutat Res; 2007 Mar; 628(1):31-55. PubMed ID: 17293159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice.
    Battershill JM; Fielder RJ
    Hum Exp Toxicol; 1998 Apr; 17(4):193-205. PubMed ID: 9617631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of human carcinogens.
    Barrett JC; Shelby MD
    Prog Clin Biol Res; 1992; 374():415-34. PubMed ID: 1620716
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge.
    Wolf DC; Cohen SM; Boobis AR; Dellarco VL; Fenner-Crisp PA; Moretto A; Pastoor TP; Schoeny RS; Seed JG; Doe JE
    Regul Toxicol Pharmacol; 2019 Apr; 103():86-92. PubMed ID: 30634023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carcinogenicity of the aromatic amines: from structure-activity relationships to mechanisms of action and risk assessment.
    Benigni R; Passerini L
    Mutat Res; 2002 Jul; 511(3):191-206. PubMed ID: 12088717
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA reactive and epigenetic carcinogens.
    Williams GM
    Exp Toxicol Pathol; 1992 Dec; 44(8):457-63. PubMed ID: 1493364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database.
    Sasaki YF; Sekihashi K; Izumiyama F; Nishidate E; Saga A; Ishida K; Tsuda S
    Crit Rev Toxicol; 2000 Nov; 30(6):629-799. PubMed ID: 11145306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemically induced renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information.
    Lock EA; Hard GC
    Crit Rev Toxicol; 2004; 34(3):211-99. PubMed ID: 15239388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Implications of multiple mechanisms of carcinogenesis for short-term testing.
    Harper BL; Morris DL
    Teratog Carcinog Mutagen; 1984; 4(6):483-503. PubMed ID: 6151260
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic carcinogens: evaluation and risk assessment.
    Williams GM; Whysner J
    Exp Toxicol Pathol; 1996 Feb; 48(2-3):189-95. PubMed ID: 8672874
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Is current risk assessment of non-genotoxic carcinogens protective?
    Braakhuis HM; Slob W; Olthof ED; Wolterink G; Zwart EP; Gremmer ER; Rorije E; van Benthem J; Woutersen R; van der Laan JW; Luijten M
    Crit Rev Toxicol; 2018 Jul; 48(6):500-511. PubMed ID: 29745287
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods.
    Waters MD; Jackson M; Lea I
    Mutat Res; 2010 Dec; 705(3):184-200. PubMed ID: 20399889
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.