BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

732 related articles for article (PubMed ID: 31000598)

  • 1. Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
    Lim JKM; Delaidelli A; Minaker SW; Zhang HF; Colovic M; Yang H; Negri GL; von Karstedt S; Lockwood WW; Schaffer P; Leprivier G; Sorensen PH
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9433-9442. PubMed ID: 31000598
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The impact of oncogenic RAS on redox balance and implications for cancer development.
    Lim JKM; Leprivier G
    Cell Death Dis; 2019 Dec; 10(12):955. PubMed ID: 31852884
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
    DeNicola GM; Karreth FA; Humpton TJ; Gopinathan A; Wei C; Frese K; Mangal D; Yu KH; Yeo CJ; Calhoun ES; Scrimieri F; Winter JM; Hruban RH; Iacobuzio-Donahue C; Kern SE; Blair IA; Tuveson DA
    Nature; 2011 Jul; 475(7354):106-9. PubMed ID: 21734707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma.
    Hu K; Li K; Lv J; Feng J; Chen J; Wu H; Cheng F; Jiang W; Wang J; Pei H; Chiao PJ; Cai Z; Chen Y; Liu M; Pang X
    J Clin Invest; 2020 Apr; 130(4):1752-1766. PubMed ID: 31874110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation.
    Sheffels E; Sealover NE; Wang C; Kim DH; Vazirani IA; Lee E; M Terrell E; Morrison DK; Luo J; Kortum RL
    Sci Signal; 2018 Sep; 11(546):. PubMed ID: 30181243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity.
    Arensman MD; Yang XS; Leahy DM; Toral-Barza L; Mileski M; Rosfjord EC; Wang F; Deng S; Myers JS; Abraham RT; Eng CH
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9533-9542. PubMed ID: 31019077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
    Habib E; Linher-Melville K; Lin HX; Singh G
    Redox Biol; 2015 Aug; 5():33-42. PubMed ID: 25827424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C-Raf-1 protein kinase is not essential for Ras transformation of mouse embryo fibroblasts.
    Gupta AK; Bernhard EJ; Bakanauskas VJ; Cerniglia GJ; Muschel RJ; McKenna G
    Cancer Biol Ther; 2003; 2(1):73-5. PubMed ID: 12673122
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTH1 expression is required for effective transformation by oncogenic HRAS.
    Giribaldi MG; Munoz A; Halvorsen K; Patel A; Rai P
    Oncotarget; 2015 May; 6(13):11519-29. PubMed ID: 25893378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cystine/glutamate antiporter xCT deficiency reduces metastasis without impairing immune system function in breast cancer mouse models.
    Ruiu R; Cossu C; Iacoviello A; Conti L; Bolli E; Ponzone L; Magri J; Rumandla A; Calautti E; Cavallo F
    J Exp Clin Cancer Res; 2023 Sep; 42(1):254. PubMed ID: 37770957
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S.
    Huang L; Counter CM
    PLoS One; 2015; 10(4):e0123918. PubMed ID: 25902334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced expression of cystine/glutamate transporter in the lung caused by the oxidative-stress-inducing agent paraquat.
    Kobayashi S; Kuwata K; Sugimoto T; Igarashi K; Osaki M; Okada F; Fujii J; Bannai S; Sato H
    Free Radic Biol Med; 2012 Dec; 53(12):2197-203. PubMed ID: 23085521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate.
    Koppula P; Zhang Y; Shi J; Li W; Gan B
    J Biol Chem; 2017 Aug; 292(34):14240-14249. PubMed ID: 28630042
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression.
    Barradas M; Monjas A; Diaz-Meco MT; Serrano M; Moscat J
    EMBO J; 1999 Nov; 18(22):6362-9. PubMed ID: 10562548
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells.
    Bjørndal B; Myklebust LM; Rosendal KR; Myromslien FD; Lorens JB; Nolan G; Bruland O; Lillehaug JR
    Int J Cancer; 2007 Mar; 120(5):961-9. PubMed ID: 17149700
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of Nrf2 on tumour growth and drug sensitivity in oncogenic K-ras-transformed cells in vitro and in vivo.
    Shao J; Glorieux C; Liao J; Chen P; Lu W; Liang Z; Wen S; Hu Y; Huang P
    Free Radic Res; 2018 Jun; 52(6):661-671. PubMed ID: 29621903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.
    Kent OA; Sandí MJ; Burston HE; Brown KR; Rottapel R
    Oncotarget; 2017 Jan; 8(3):4484-4500. PubMed ID: 27835861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Redox imbalance in cystine/glutamate transporter-deficient mice.
    Sato H; Shiiya A; Kimata M; Maebara K; Tamba M; Sakakura Y; Makino N; Sugiyama F; Yagami K; Moriguchi T; Takahashi S; Bannai S
    J Biol Chem; 2005 Nov; 280(45):37423-9. PubMed ID: 16144837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury.
    Meyer AR; Engevik AC; Willet SG; Williams JA; Zou Y; Massion PP; Mills JC; Choi E; Goldenring JR
    Cell Mol Gastroenterol Hepatol; 2019; 8(3):379-405. PubMed ID: 31071489
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.