BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

408 related articles for article (PubMed ID: 31004319)

  • 1. LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease.
    Van Gool B; Storck SE; Reekmans SM; Lechat B; Gordts PLSM; Pradier L; Pietrzik CU; Roebroek AJM
    Mol Neurobiol; 2019 Oct; 56(10):7234-7245. PubMed ID: 31004319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
    Liu CC; Hu J; Zhao N; Wang J; Wang N; Cirrito JR; Kanekiyo T; Holtzman DM; Bu G
    J Neurosci; 2017 Apr; 37(15):4023-4031. PubMed ID: 28275161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional role of lipoprotein receptors in Alzheimer's disease.
    Jaeger S; Pietrzik CU
    Curr Alzheimer Res; 2008 Feb; 5(1):15-25. PubMed ID: 18288927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neuronal clearance of amyloid-β by endocytic receptor LRP1.
    Kanekiyo T; Cirrito JR; Liu CC; Shinohara M; Li J; Schuler DR; Shinohara M; Holtzman DM; Bu G
    J Neurosci; 2013 Dec; 33(49):19276-83. PubMed ID: 24305823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.
    Kanekiyo T; Liu CC; Shinohara M; Li J; Bu G
    J Neurosci; 2012 Nov; 32(46):16458-65. PubMed ID: 23152628
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low-Density Lipoprotein Receptor-Related Protein-1 (LRP1) C4408R Mutant Promotes Amyloid Precursor Protein (APP) α-Cleavage in Vitro.
    Hou H; Habib A; Zi D; Tian K; Tian J; Giunta B; Sawmiller D; Tan J
    Neuromolecular Med; 2017 Sep; 19(2-3):300-308. PubMed ID: 28612181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.
    Xiao Q; Yan P; Ma X; Liu H; Perez R; Zhu A; Gonzales E; Tripoli DL; Czerniewski L; Ballabio A; Cirrito JR; Diwan A; Lee JM
    J Neurosci; 2015 Sep; 35(35):12137-51. PubMed ID: 26338325
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of High Cholesterol Regulation of LRP1 and RAGE on Aβ Transport Across the Blood-Brain Barrier in Alzheimer's Disease.
    Zhou R; Chen LL; Yang H; Li L; Liu J; Chen L; Hong WJ; Wang CG; Ma JJ; Huang J; Zhou XF; Liu D; Zhou HD
    Curr Alzheimer Res; 2021; 18(5):428-442. PubMed ID: 34488598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
    Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
    Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of LRP1 in Aβ efflux transport across the blood-brain barrier and cognitive dysfunction in diabetes mellitus.
    P X; Zz L; Gg J; Lp W; Cm B; Yl W; Chen MF; W L
    Neurochem Int; 2022 Nov; 160():105417. PubMed ID: 36067928
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
    Fanaee-Danesh E; Gali CC; Tadic J; Zandl-Lang M; Carmen Kober A; Agujetas VR; de Dios C; Tam-Amersdorfer C; Stracke A; Albrecher NM; Manavalan APC; Reiter M; Sun Y; Colell A; Madeo F; Malle E; Panzenboeck U
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2224-2245. PubMed ID: 31055081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
    Storck SE; Hartz AMS; Bernard J; Wolf A; Kachlmeier A; Mahringer A; Weggen S; Pahnke J; Pietrzik CU
    Brain Behav Immun; 2018 Oct; 73():21-33. PubMed ID: 30041013
    [TBL] [Abstract][Full Text] [Related]  

  • 14. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
    Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
    J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
    Zandl-Lang M; Fanaee-Danesh E; Sun Y; Albrecher NM; Gali CC; Čančar I; Kober A; Tam-Amersdorfer C; Stracke A; Storck SM; Saeed A; Stefulj J; Pietrzik CU; Wilson MR; Björkhem I; Panzenboeck U
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Jan; 1863(1):40-60. PubMed ID: 28941799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.
    Storck SE; Pietrzik CU
    Pharm Res; 2017 Dec; 34(12):2637-2651. PubMed ID: 28948494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways.
    O'Callaghan P; Noborn F; Sehlin D; Li JP; Lannfelt L; Lindahl U; Zhang X
    Amyloid; 2014 Jun; 21(2):76-87. PubMed ID: 24491019
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier.
    Pflanzner T; Janko MC; André-Dohmen B; Reuss S; Weggen S; Roebroek AJ; Kuhlmann CR; Pietrzik CU
    Neurobiol Aging; 2011 Dec; 32(12):2323.e1-11. PubMed ID: 20630619
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
    Storck SE; Meister S; Nahrath J; Meißner JN; Schubert N; Di Spiezio A; Baches S; Vandenbroucke RE; Bouter Y; Prikulis I; Korth C; Weggen S; Heimann A; Schwaninger M; Bayer TA; Pietrzik CU
    J Clin Invest; 2016 Jan; 126(1):123-36. PubMed ID: 26619118
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid.
    Pan Y; Short JL; Newman SA; Choy KHC; Tiwari D; Yap C; Senyschyn D; Banks WA; Nicolazzo JA
    Brain Behav Immun; 2018 May; 70():36-47. PubMed ID: 29545118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.