BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 31004362)

  • 1. 9za plays cytotoxic and proapoptotic roles and induces cytoprotective autophagy through the PDK1/Akt/mTOR axis in non-small-cell lung cancer.
    Liu R; Chen Z; Yi X; Huang F; Hu G; Liu D; Li X; Zhou H; Liu Z
    J Cell Physiol; 2019 Nov; 234(11):20728-20741. PubMed ID: 31004362
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives.
    Yu Z; Chen Z; Su Q; Ye S; Yuan H; Kuai M; Lv M; Tu Z; Yang X; Liu R; Hu G; Li Q
    Bioorg Med Chem; 2019 Mar; 27(6):944-954. PubMed ID: 30777660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G
    Liu R; Yu Z; Chen Z; Liu D; Huang F; Li Q; Hu G; Yi X; Li X; Zhou H; Liu Z
    PeerJ; 2020; 8():e9981. PubMed ID: 33072436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Luteoloside induces G
    Zhou M; Shen S; Zhao X; Gong X
    Biochem Biophys Res Commun; 2017 Dec; 494(1-2):263-269. PubMed ID: 29024631
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
    Wen Q; Wang W; Luo J; Chu S; Chen L; Xu L; Zang H; Alnemah MM; Ma J; Fan S
    Oncotarget; 2016 May; 7(19):27787-801. PubMed ID: 27050281
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer.
    Hsu JL; Leu WJ; Zhong NS; Guh JH
    Molecules; 2021 Oct; 26(19):. PubMed ID: 34641511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.
    Ling YH; Aracil M; Zou Y; Yuan Z; Lu B; Jimeno J; Cuervo AM; Perez-Soler R
    Clin Cancer Res; 2011 Aug; 17(16):5353-66. PubMed ID: 21690574
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells.
    Hung JY; Hsu YL; Li CT; Ko YC; Ni WC; Huang MS; Kuo PL
    J Agric Food Chem; 2009 Oct; 57(20):9809-16. PubMed ID: 19799425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cinnamtannin D1 from Rhododendron formosanum Induces Autophagy via the Inhibition of Akt/mTOR and Activation of ERK1/2 in Non-Small-Cell Lung Carcinoma Cells.
    Way TD; Tsai SJ; Wang CM; Jhan YL; Ho CT; Chou CH
    J Agric Food Chem; 2015 Dec; 63(48):10407-17. PubMed ID: 26567590
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells.
    Sun Y; Huang YH; Huang FY; Mei WL; Liu Q; Wang CC; Lin YY; Huang C; Li YN; Dai HF; Tan GH
    Theranostics; 2018; 8(7):2044-2060. PubMed ID: 29556372
    [No Abstract]   [Full Text] [Related]  

  • 11. Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.
    Khan N; Afaq F; Khusro FH; Mustafa Adhami V; Suh Y; Mukhtar H
    Int J Cancer; 2012 Apr; 130(7):1695-705. PubMed ID: 21618507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma.
    Bamodu OA; Chang HL; Ong JR; Lee WH; Yeh CT; Tsai JT
    Cells; 2020 Mar; 9(3):. PubMed ID: 32197467
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivated Sendai virus induces apoptosis and autophagy via the PI3K/Akt/mTOR/p70S6K pathway in human non-small cell lung cancer cells.
    Zhang Q; Zhu H; Xu X; Li L; Tan H; Cai X
    Biochem Biophys Res Commun; 2015 Sep; 465(1):64-70. PubMed ID: 26235873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ganoderic acid DM induces autophagic apoptosis in non-small cell lung cancer cells by inhibiting the PI3K/Akt/mTOR activity.
    Xia J; Dai L; Wang L; Zhu J
    Chem Biol Interact; 2020 Jan; 316():108932. PubMed ID: 31874162
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel hybrid of 3-benzyl coumarin seco-B-ring derivative and phenylsulfonylfuroxan induces apoptosis and autophagy in non-small-cell lung cancer.
    Dong M; Ye T; Bi Y; Wang Q; Kuerban K; Li J; Feng M; Wang K; Chen Y; Ye L
    Phytomedicine; 2019 Jan; 52():79-88. PubMed ID: 30599915
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunomodulatory Protein from Ganoderma microsporum Induces Pro-Death Autophagy through Akt-mTOR-p70S6K Pathway Inhibition in Multidrug Resistant Lung Cancer Cells.
    Chiu LY; Hu ME; Yang TY; Hsin IL; Ko JL; Tsai KJ; Sheu GT
    PLoS One; 2015; 10(5):e0125774. PubMed ID: 25946033
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.
    Wang F; Mao Y; You Q; Hua D; Cai D
    Int J Immunopathol Pharmacol; 2015 Sep; 28(3):362-73. PubMed ID: 26246196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY; Hwangbo H; Kim MY; Ji SY; Lee H; Kim GY; Kwon CY; Leem SH; Hong SH; Cheong J; Choi YH
    Arch Biochem Biophys; 2021 Jan; 697():108688. PubMed ID: 33227289
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway.
    Liu F; Gao S; Yang Y; Zhao X; Fan Y; Ma W; Yang D; Yang A; Yu Y
    Oncol Rep; 2018 Mar; 39(3):1523-1531. PubMed ID: 29328421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.
    Tan J; Li Z; Lee PL; Guan P; Aau MY; Lee ST; Feng M; Lim CZ; Lee EY; Wee ZN; Lim YC; Karuturi RK; Yu Q
    Cancer Discov; 2013 Oct; 3(10):1156-71. PubMed ID: 23887393
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.