163 related articles for article (PubMed ID: 3100797)
1. Folate analogues. 25. Synthesis and biological evaluation of N10-propargylfolic acid and its reduced derivatives.
Ghazala M; Nair MG; Toghiyani TR; Kisliuk RL; Gaumont Y; Kalman TI
J Med Chem; 1986 Jul; 29(7):1263-9. PubMed ID: 3100797
[TBL] [Abstract][Full Text] [Related]
2. Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF).
Nair MG; Nanavati NT; Nair IG; Kisliuk RL; Gaumont Y; Hsiao MC; Kalman TI
J Med Chem; 1986 Sep; 29(9):1754-60. PubMed ID: 3091832
[TBL] [Abstract][Full Text] [Related]
3. Folate analogues. 30. Synthesis and biological evaluation of N10-propargyl-5,8-dideaza-5,6,7,8-tetrahydrofolic acid and related compounds.
Nair MG; Dhawan R; Ghazala M; Kalman TI; Ferone R; Gaumont Y; Kisliuk RL
J Med Chem; 1987 Jul; 30(7):1256-61. PubMed ID: 3599032
[TBL] [Abstract][Full Text] [Related]
4. Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.
Patil SD; Jones C; Nair MG; Galivan J; Maley F; Kisliuk RL; Gaumont Y; Duch D; Ferone R
J Med Chem; 1989 Jun; 32(6):1284-9. PubMed ID: 2542557
[TBL] [Abstract][Full Text] [Related]
5. Folate analogues altered in the C9-N10 bridge region: N10-Toxylisohomofolic acid and N10-Toxylisohomoaminopterin.
Nair MG; O'Neal PC; Baugh CM; Kisliuk RL; Gaumont Y; Rodman M
J Med Chem; 1978 Jul; 21(7):673-7. PubMed ID: 97383
[No Abstract] [Full Text] [Related]
6. Folate analogues. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid.
Nair MG; Salter DC; Kisliuk RL; Gaumont Y; North G; Sirotnak FM
J Med Chem; 1983 Apr; 26(4):605-7. PubMed ID: 6403710
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin.
Piper JR; Malik ND; Rhee MS; Galivan J; Sirotnak FM
J Med Chem; 1992 Jan; 35(2):332-7. PubMed ID: 1732551
[TBL] [Abstract][Full Text] [Related]
8. Quinazoline antifolate thymidylate synthase inhibitors: 2'-fluoro-N10-propargyl-5,8-dideazafolic acid and derivatives with modifications in the C2 position.
Jackman AL; Marsham PR; Thornton TJ; Bishop JA; O'Connor BM; Hughes LR; Calvert AH; Jones TR
J Med Chem; 1990 Nov; 33(11):3067-71. PubMed ID: 2231607
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative.
DeGraw JI; Colwell WT; Brown VH; Sato M; Kisliuk RL; Gaumont Y; Thorndike J; Sirotnak FM
J Med Chem; 1988 Jan; 31(1):150-3. PubMed ID: 3121855
[TBL] [Abstract][Full Text] [Related]
10. Folate analogues. 20. Synthesis and antifolate activity of 1',2',3',4',5',6'-hexahydrohomofolic acid.
Nair MG; Otis EB; Kisliuk RL; Gaumont Y
J Med Chem; 1983 Feb; 26(2):135-40. PubMed ID: 6827531
[TBL] [Abstract][Full Text] [Related]
11. Quinazoline antifolates inhibiting thymidylate synthase: benzoyl ring modifications.
Jones TR; Smithers MJ; Taylor MA; Jackman AL; Calvert AH; Harland SJ; Harrap KR
J Med Chem; 1986 Apr; 29(4):468-72. PubMed ID: 3754284
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of aza homologues of folic acid.
Martinelli JE; Chaykovsky M; Kisliuk RL; Gaumont Y
J Med Chem; 1979 Jul; 22(7):874-7. PubMed ID: 109617
[TBL] [Abstract][Full Text] [Related]
13. Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.
Cheng YC; Dutschman GE; Starnes MC; Fisher MH; Nanavathi NT; Nair MG
Cancer Res; 1985 Feb; 45(2):598-600. PubMed ID: 3917852
[TBL] [Abstract][Full Text] [Related]
14. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo.
Jackman AL; Taylor GA; O'Connor BM; Bishop JA; Moran RG; Calvert AH
Cancer Res; 1990 Sep; 50(17):5212-8. PubMed ID: 2386929
[TBL] [Abstract][Full Text] [Related]
15. Folate analogues altered in the C9--N10 bridge region. 14. 11-Oxahomofolic acid, a potential antitumor agent.
Nair MG; Saunders C; Chen SY; Kisliuk RL; Gaumont Y
J Med Chem; 1980 Jan; 23(1):59-65. PubMed ID: 6767031
[No Abstract] [Full Text] [Related]
16. Folate analogues. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferase.
Nair MG; Murthy BR; Patil SD; Kisliuk RL; Thorndike J; Gaumont Y; Ferone R; Duch DS; Edelstein MP
J Med Chem; 1989 Jun; 32(6):1277-83. PubMed ID: 2498518
[TBL] [Abstract][Full Text] [Related]
17. Folate analogues altered in the C9-N10 bridge region. 16. Synthesis and antifolate activity of 11-thiohomoaminopterin.
Nair MG; Chen SY; Kisliuk RL; Gaumont Y; Strumpf D
J Med Chem; 1980 Aug; 23(8):899-903. PubMed ID: 6772788
[TBL] [Abstract][Full Text] [Related]
18. Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid.
Li SW; Nair MG; Edwards DM; Kisliuk RL; Gaumont Y; Dev IK; Duch DS; Humphreys J; Smith GK; Ferone R
J Med Chem; 1991 Sep; 34(9):2746-54. PubMed ID: 1895294
[TBL] [Abstract][Full Text] [Related]
19. Polyglutamyl and polylysyl derivatives of the lysine analogues of folic acid and homofolic acid.
Plante LT; Crawford EJ; Friedkin M
J Med Chem; 1976 Nov; 19(11):1295-9. PubMed ID: 794472
[TBL] [Abstract][Full Text] [Related]
20. Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
Bavetsias V; Jackman AL; Kimbell R; Gibson W; Boyle FT; Bisset GM
J Med Chem; 1996 Jan; 39(1):73-85. PubMed ID: 8568829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]