These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 31011505)

  • 1. Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
    Sorrentino L; Cossu F; Milani M; Malkoc B; Huang WC; Tsay SC; Ru Hwu J; Mastrangelo E
    ChemistryOpen; 2019 Apr; 8(4):476-482. PubMed ID: 31011505
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway.
    Cossu F; Milani M; Grassi S; Malvezzi F; Corti A; Bolognesi M; Mastrangelo E
    Proteins; 2015 Apr; 83(4):612-20. PubMed ID: 25619915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
    Lu M; Lin SC; Huang Y; Kang YJ; Rich R; Lo YC; Myszka D; Han J; Wu H
    Mol Cell; 2007 Jun; 26(5):689-702. PubMed ID: 17560374
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases.
    Samuel T; Welsh K; Lober T; Togo SH; Zapata JM; Reed JC
    J Biol Chem; 2006 Jan; 281(2):1080-90. PubMed ID: 16282325
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational and Experimental Characterization of NF023, A Candidate Anticancer Compound Inhibiting cIAP2/TRAF2 Assembly.
    Cossu F; Sorrentino L; Fagnani E; Zaffaroni M; Milani M; Giorgino T; Mastrangelo E
    J Chem Inf Model; 2020 Oct; 60(10):5036-5044. PubMed ID: 32820924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the BIR1 domain of XIAP in two crystal forms.
    Lin SC; Huang Y; Lo YC; Lu M; Wu H
    J Mol Biol; 2007 Sep; 372(4):847-854. PubMed ID: 17698078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrity of XIAP is essential for effective activity recovery of apoptosome and its downstream caspases by Smac/Diablo.
    Attaran-Bandarabadi F; Abhari BA; Neishabouri SH; Davoodi J
    Int J Biol Macromol; 2017 Aug; 101():283-289. PubMed ID: 28322955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-κB pathway.
    Cossu F; Camelliti S; Lecis D; Sorrentino L; Majorini MT; Milani M; Mastrangelo E
    Comput Struct Biotechnol J; 2021; 19():6366-6374. PubMed ID: 34938412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A single BIR domain of XIAP sufficient for inhibiting caspases.
    Takahashi R; Deveraux Q; Tamm I; Welsh K; Assa-Munt N; Salvesen GS; Reed JC
    J Biol Chem; 1998 Apr; 273(14):7787-90. PubMed ID: 9525868
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells.
    Fiore M; Mosconi M; Bonì F; Parodi A; Salis A; Tasso B; Mastrangelo E; Millo E; Cossu F
    Molecules; 2023 Jan; 28(1):. PubMed ID: 36615638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
    Mastrangelo E; Cossu F; Milani M; Sorrentino G; Lecis D; Delia D; Manzoni L; Drago C; Seneci P; Scolastico C; Rizzo V; Bolognesi M
    J Mol Biol; 2008 Dec; 384(3):673-89. PubMed ID: 18851976
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
    Cossu F; Milani M; Vachette P; Malvezzi F; Grassi S; Lecis D; Delia D; Drago C; Seneci P; Bolognesi M; Mastrangelo E
    PLoS One; 2012; 7(11):e49527. PubMed ID: 23166698
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
    Deveraux QL; Leo E; Stennicke HR; Welsh K; Salvesen GS; Reed JC
    EMBO J; 1999 Oct; 18(19):5242-51. PubMed ID: 10508158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.
    Garrison JB; Samuel T; Reed JC
    Oncogene; 2009 Apr; 28(13):1584-93. PubMed ID: 19234489
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural analysis of the UBA domain of X-linked inhibitor of apoptosis protein reveals different surfaces for ubiquitin-binding and self-association.
    Tse MK; Hui SK; Yang Y; Yin ST; Hu HY; Zou B; Wong BC; Sze KH
    PLoS One; 2011; 6(12):e28511. PubMed ID: 22194841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP.
    Hou MM; Polykretis P; Luchinat E; Wang X; Chen SN; Zuo HH; Yang Y; Chen JL; Ye Y; Li C; Banci L; Su XC
    Sci Rep; 2017 Nov; 7(1):16630. PubMed ID: 29192194
    [TBL] [Abstract][Full Text] [Related]  

  • 17. X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression.
    Neil JR; Tian M; Schiemann WP
    J Biol Chem; 2009 Aug; 284(32):21209-17. PubMed ID: 19531477
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-κB activation and apoptosis in P19 cells.
    Rochira JA; Matluk NN; Adams TL; Karaczyn AA; Oxburgh L; Hess ST; Verdi JM
    PLoS One; 2011; 6(7):e20659. PubMed ID: 21789165
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
    Kester RF; Donnell AF; Lou Y; Remiszewski SW; Lombardo LJ; Chen S; Le NT; Lo J; Moliterni JA; Han X; Hogg JH; Liang W; Michoud C; Rupert KC; Mischke S; Le K; Weisel M; Janson CA; Lukacs CM; Fretland AJ; Hong K; Polonskaia A; Gao L; Li S; Solis DS; Aguilar D; Tardell C; Dvorozniak M; Tannu S; Lee EC; Schutt AD; Goggin B
    J Med Chem; 2013 Oct; 56(20):7788-803. PubMed ID: 24093940
    [TBL] [Abstract][Full Text] [Related]  

  • 20. X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.
    Obexer P; Ausserlechner MJ
    Front Oncol; 2014; 4():197. PubMed ID: 25120954
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.