286 related articles for article (PubMed ID: 31015445)
1. PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.
Miyakawa K; Matsunaga S; Yokoyama M; Nomaguchi M; Kimura Y; Nishi M; Kimura H; Sato H; Hirano H; Tamura T; Akari H; Miura T; Adachi A; Sawasaki T; Yamamoto N; Ryo A
Nat Commun; 2019 Apr; 10(1):1844. PubMed ID: 31015445
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly.
Wang H; Guo H; Su J; Rui Y; Zheng W; Gao W; Zhang W; Li Z; Liu G; Markham RB; Wei W; Yu XF
J Virol; 2017 May; 91(9):. PubMed ID: 28202763
[TBL] [Abstract][Full Text] [Related]
3. Immune Activation Influences SAMHD1 Expression and Vpx-mediated SAMHD1 Degradation during Chronic HIV-1 Infection.
Fu W; Qiu C; Zhou M; Zhu L; Yang Y; Qiu C; Zhang L; Xu X; Wang Y; Xu J; Zhang X
Sci Rep; 2016 Dec; 6():38162. PubMed ID: 27922067
[TBL] [Abstract][Full Text] [Related]
4. Determinants of lentiviral Vpx-CRL4 E3 ligase-mediated SAMHD1 degradation in the substrate adaptor protein DCAF1.
Guo H; Zhang N; Shen S; Yu XF; Wei W
Biochem Biophys Res Commun; 2019 Jun; 513(4):933-939. PubMed ID: 31003777
[TBL] [Abstract][Full Text] [Related]
5. Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
Martin MM; Matkovic R; Larrous P; Morel M; Lasserre A; Vauthier V; Margottin-Goguet F
PLoS Pathog; 2021 Oct; 17(10):e1009609. PubMed ID: 34699574
[TBL] [Abstract][Full Text] [Related]
6. Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection.
Cingöz O; Arnow ND; Puig Torrents M; Bannert N
Retrovirology; 2021 Feb; 18(1):4. PubMed ID: 33563288
[TBL] [Abstract][Full Text] [Related]
7. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.
Fregoso OI; Ahn J; Wang C; Mehrens J; Skowronski J; Emerman M
PLoS Pathog; 2013; 9(7):e1003496. PubMed ID: 23874202
[TBL] [Abstract][Full Text] [Related]
8. The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals.
Yu H; Usmani SM; Borch A; Krämer J; Stürzel CM; Khalid M; Li X; Krnavek D; van der Ende ME; Osterhaus AD; Gruters RA; Kirchhoff F
Retrovirology; 2013 Mar; 10():27. PubMed ID: 23497283
[TBL] [Abstract][Full Text] [Related]
9. Degradation of SAMHD1 by Vpx Is Independent of Uncoating.
Jáuregui P; Logue EC; Schultz ML; Fung S; Landau NR
J Virol; 2015 May; 89(10):5701-13. PubMed ID: 25762741
[TBL] [Abstract][Full Text] [Related]
10. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
Baldauf HM; Stegmann L; Schwarz SM; Ambiel I; Trotard M; Martin M; Burggraf M; Lenzi GM; Lejk H; Pan X; Fregoso OI; Lim ES; Abraham L; Nguyen LA; Rutsch F; König R; Kim B; Emerman M; Fackler OT; Keppler OT
Proc Natl Acad Sci U S A; 2017 Mar; 114(10):2729-2734. PubMed ID: 28228523
[TBL] [Abstract][Full Text] [Related]
11. HIV-2 Vpx neutralizes host restriction factor SAMHD1 to promote viral pathogenesis.
Mohamed A; Bakir T; Al-Hawel H; Al-Sharif I; Bakheet R; Kouser L; Murugaiah V; Al-Mozaini M
Sci Rep; 2021 Oct; 11(1):20984. PubMed ID: 34697376
[TBL] [Abstract][Full Text] [Related]
12. Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
Sliva K; Martin J; von Rhein C; Herrmann T; Weyrich A; Toda M; Schnierle BS
J Virol; 2019 Nov; 93(22):. PubMed ID: 31462561
[TBL] [Abstract][Full Text] [Related]
13. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Wu Y; Koharudin LMI; Mehrens J; DeLucia M; Byeon CH; Byeon IL; Calero G; Ahn J; Gronenborn AM
J Biol Chem; 2015 Jul; 290(29):17935-17945. PubMed ID: 26045556
[TBL] [Abstract][Full Text] [Related]
14. HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1.
Luo X; Herzig E; Doitsh G; Grimmett ZW; Muñoz-Arias I; Greene WC
J Virol; 2019 Dec; 93(24):. PubMed ID: 31578293
[TBL] [Abstract][Full Text] [Related]
15. HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
Ahn J; Hao C; Yan J; DeLucia M; Mehrens J; Wang C; Gronenborn AM; Skowronski J
J Biol Chem; 2012 Apr; 287(15):12550-8. PubMed ID: 22362772
[TBL] [Abstract][Full Text] [Related]
16. [Research Progress in Viral Protein Vpx induction of Proteasomal Degradation of the Antiviral Factor SAMHD1].
Hou J; Du J; Zhao K; Yu X
Bing Du Xue Bao; 2016 May; 32(3):355-60. PubMed ID: 29963825
[TBL] [Abstract][Full Text] [Related]
17. Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
Bowen NE; Tao S; Cho YJ; Schinazi RF; Kim B
J Biol Chem; 2023 Aug; 299(8):104984. PubMed ID: 37390988
[TBL] [Abstract][Full Text] [Related]
18. HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.
DeLucia M; Mehrens J; Wu Y; Ahn J
J Biol Chem; 2013 Jun; 288(26):19116-26. PubMed ID: 23677995
[TBL] [Abstract][Full Text] [Related]
19. Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
Yurkovetskiy L; Guney MH; Kim K; Goh SL; McCauley S; Dauphin A; Diehl WE; Luban J
Nat Microbiol; 2018 Dec; 3(12):1354-1361. PubMed ID: 30297740
[TBL] [Abstract][Full Text] [Related]
20. Structural basis of lentiviral subversion of a cellular protein degradation pathway.
Schwefel D; Groom HC; Boucherit VC; Christodoulou E; Walker PA; Stoye JP; Bishop KN; Taylor IA
Nature; 2014 Jan; 505(7482):234-8. PubMed ID: 24336198
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
