BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 31025074)

  • 1. The secondary metabolite pactamycin with potential for pharmaceutical applications: biosynthesis and regulation.
    Eida AA; Mahmud T
    Appl Microbiol Biotechnol; 2019 Jun; 103(11):4337-4345. PubMed ID: 31025074
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues.
    Abugrain ME; Lu W; Li Y; Serrill JD; Brumsted CJ; Osborn AR; Alani A; Ishmael JE; Kelly JX; Mahmud T
    Chembiochem; 2016 Sep; 17(17):1585-8. PubMed ID: 27305101
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Global and pathway-specific transcriptional regulations of pactamycin biosynthesis in Streptomyces pactum.
    Lu W; Alanzi AR; Abugrain ME; Ito T; Mahmud T
    Appl Microbiol Biotechnol; 2018 Dec; 102(24):10589-10601. PubMed ID: 30276712
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Directed biosynthesis of 5"-fluoropactamycin in Streptomyces pactum.
    Adams ES; Rinehart KL
    J Antibiot (Tokyo); 1994 Dec; 47(12):1456-65. PubMed ID: 7844040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deciphering pactamycin biosynthesis and engineered production of new pactamycin analogues.
    Ito T; Roongsawang N; Shirasaka N; Lu W; Flatt PM; Kasanah N; Miranda C; Mahmud T
    Chembiochem; 2009 Sep; 10(13):2253-65. PubMed ID: 19670201
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biosynthetic studies and genetic engineering of pactamycin analogs with improved selectivity toward malarial parasites.
    Lu W; Roongsawang N; Mahmud T
    Chem Biol; 2011 Apr; 18(4):425-31. PubMed ID: 21513878
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pactamycin production by Streptomyces pactum.
    BHUYAN BK
    Appl Microbiol; 1962 Jul; 10(4):302-4. PubMed ID: 13868850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cloning of the pactamycin biosynthetic gene cluster and characterization of a crucial glycosyltransferase prior to a unique cyclopentane ring formation.
    Kudo F; Kasama Y; Hirayama T; Eguchi T
    J Antibiot (Tokyo); 2007 Aug; 60(8):492-503. PubMed ID: 17827660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity.
    Almabruk KH; Lu W; Li Y; Abugreen M; Kelly JX; Mahmud T
    Org Lett; 2013 Apr; 15(7):1678-81. PubMed ID: 23521145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glycosylation of acyl carrier protein-bound polyketides during pactamycin biosynthesis.
    Eida AA; Abugrain ME; Brumsted CJ; Mahmud T
    Nat Chem Biol; 2019 Aug; 15(8):795-802. PubMed ID: 31308531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-specific methylation of 16S rRNA caused by pct, a pactamycin resistance determinant from the producing organism, Streptomyces pactum.
    Ballesta JP; Cundliffe E
    J Bacteriol; 1991 Nov; 173(22):7213-8. PubMed ID: 1657884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation.
    Aparicio JF; Barreales EG; Payero TD; Vicente CM; de Pedro A; Santos-Aberturas J
    Appl Microbiol Biotechnol; 2016 Jan; 100(1):61-78. PubMed ID: 26512010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of Specialized Metabolite Production in Genetically Engineered
    Ju Z; Zhou W; Alharbi HA; Howell DC; Mahmud T
    ACS Chem Biol; 2021 Nov; 16(11):2641-2650. PubMed ID: 34723462
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional Characterization of 3-Aminobenzoic Acid Adenylation Enzyme PctU and UDP-N-Acetyl-d-Glucosamine: 3-Aminobenzoyl-ACP Glycosyltransferase PctL in Pactamycin Biosynthesis.
    Kudo F; Zhang J; Sato S; Hirayama A; Eguchi T
    Chembiochem; 2019 Oct; 20(19):2458-2462. PubMed ID: 31059166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Use of a fractionated coupled transcription-translation system in the study of ribosomal resistance mechanisms in antibiotic-producing Streptomyces.
    Calcutt MJ; Cundliffe E
    J Gen Microbiol; 1989 May; 135(5):1071-81. PubMed ID: 2621447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioinformatics-guided connection of a biosynthetic gene cluster to the antitumor antibiotic gilvusmycin.
    Wang X; Wu S; Jin W; Xu B; Tang G; Yuan H
    Acta Biochim Biophys Sin (Shanghai); 2018 May; 50(5):516-518. PubMed ID: 29659660
    [No Abstract]   [Full Text] [Related]  

  • 17. Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production.
    Niraula NP; Kim SH; Sohng JK; Kim ES
    Appl Microbiol Biotechnol; 2010 Jul; 87(4):1187-94. PubMed ID: 20508927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A single PLP-dependent enzyme PctV catalyzes the transformation of 3-dehydroshikimate into 3-aminobenzoate in the biosynthesis of pactamycin.
    Hirayama A; Eguchi T; Kudo F
    Chembiochem; 2013 Jul; 14(10):1198-203. PubMed ID: 23744829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 8''-Hydroxypactamycin and 7-deoxypactamycin, new members of the pactamycin group.
    Dobashi K; Isshiki K; Sawa T; Obata T; Hamada M; Naganawa H; Takita T; Takeuchi T; Umezawa H; Bei HS
    J Antibiot (Tokyo); 1986 Dec; 39(12):1779-83. PubMed ID: 3818452
    [No Abstract]   [Full Text] [Related]  

  • 20. Resistance to pactamycin in clones of Streptomyces lividans containing DNA from pactamycin-producing Streptomyces pactum.
    Calcutt MJ; Cundliffe E
    Gene; 1990 Sep; 93(1):85-9. PubMed ID: 2227428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.