BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 31027213)

  • 1. Twist and Turn-Topoisomerase Functions in Mitochondrial DNA Maintenance.
    Goffart S; Hangas A; Pohjoismäki JLO
    Int J Mol Sci; 2019 Apr; 20(8):. PubMed ID: 31027213
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Controlling the topology of mammalian mitochondrial DNA.
    Menger KE; Rodríguez-Luis A; Chapman J; Nicholls TJ
    Open Biol; 2021 Sep; 11(9):210168. PubMed ID: 34547213
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trapped topoisomerase-DNA covalent complexes in the mitochondria and their role in human diseases.
    Das BB; Ghosh A; Bhattacharjee S; Bhattacharyya A
    Mitochondrion; 2021 Sep; 60():234-244. PubMed ID: 34500116
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA topoisomerases in mtDNA maintenance and ageing.
    Sobek S; Boege F
    Exp Gerontol; 2014 Aug; 56():135-41. PubMed ID: 24440386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Top3α is the replicative topoisomerase in mitochondrial DNA replication.
    Hangas A; Kekäläinen NJ; Potter A; Michell C; Aho KJ; Rutanen C; Spelbrink JN; Pohjoismäki JL; Goffart S
    Nucleic Acids Res; 2022 Aug; 50(15):8733-8748. PubMed ID: 35904803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two type I topoisomerases maintain DNA topology in human mitochondria.
    Menger KE; Chapman J; Díaz-Maldonado H; Khazeem MM; Deen D; Erdinc D; Casement JW; Di Leo V; Pyle A; Rodríguez-Luis A; Cowell IG; Falkenberg M; Austin CA; Nicholls TJ
    Nucleic Acids Res; 2022 Oct; 50(19):11154-11174. PubMed ID: 36215039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria.
    Zhang H; Zhang YW; Yasukawa T; Dalla Rosa I; Khiati S; Pommier Y
    Nucleic Acids Res; 2014 Jun; 42(11):7259-67. PubMed ID: 24803675
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA topoisomerase-targeting chemotherapeutics: what's new?
    Cuya SM; Bjornsti MA; van Waardenburg RCAM
    Cancer Chemother Pharmacol; 2017 Jul; 80(1):1-14. PubMed ID: 28528358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt).
    Dalla Rosa I; Huang SY; Agama K; Khiati S; Zhang H; Pommier Y
    J Biol Chem; 2014 Jun; 289(26):18595-602. PubMed ID: 24798329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2.
    Hangas A; Aasumets K; Kekäläinen NJ; Paloheinä M; Pohjoismäki JL; Gerhold JM; Goffart S
    Nucleic Acids Res; 2018 Oct; 46(18):9625-9636. PubMed ID: 30169847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Beyond the unwinding: role of TOP1MT in mitochondrial translation.
    Baechler SA; Dalla Rosa I; Spinazzola A; Pommier Y
    Cell Cycle; 2019 Oct; 18(19):2377-2384. PubMed ID: 31345095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chronically elevated glucose compromises myocardial mitochondrial DNA integrity by alteration of mitochondrial topoisomerase function.
    Medikayala S; Piteo B; Zhao X; Edwards JG
    Am J Physiol Cell Physiol; 2011 Feb; 300(2):C338-48. PubMed ID: 21123731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome.
    Al Khatib I; Deng J; Symes A; Kerr M; Zhang H; Huang SN; Pommier Y; Khan A; Shutt TE
    J Biol Chem; 2022 Oct; 298(10):102420. PubMed ID: 36030054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of eukaryotic topoisomerases in transcription, replication and genomic stability.
    Pommier Y; Sun Y; Huang SN; Nitiss JL
    Nat Rev Mol Cell Biol; 2016 Nov; 17(11):703-721. PubMed ID: 27649880
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial topoisomerases and alternative splicing of the human TOP1mt gene.
    Zhang H; Meng LH; Pommier Y
    Biochimie; 2007 Apr; 89(4):474-81. PubMed ID: 17161897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcription profiling suggests that mitochondrial topoisomerase IB acts as a topological barrier and regulator of mitochondrial DNA transcription.
    Dalla Rosa I; Zhang H; Khiati S; Wu X; Pommier Y
    J Biol Chem; 2017 Dec; 292(49):20162-20172. PubMed ID: 29021209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.
    Douarre C; Sourbier C; Dalla Rosa I; Brata Das B; Redon CE; Zhang H; Neckers L; Pommier Y
    PLoS One; 2012; 7(7):e41094. PubMed ID: 22911747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A truncated form of DNA topoisomerase IIbeta associates with the mtDNA genome in mammalian mitochondria.
    Low RL; Orton S; Friedman DB
    Eur J Biochem; 2003 Oct; 270(20):4173-86. PubMed ID: 14519130
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
    Khiati S; Baechler SA; Factor VM; Zhang H; Huang SY; Dalla Rosa I; Sourbier C; Neckers L; Thorgeirsson SS; Pommier Y
    Proc Natl Acad Sci U S A; 2015 Sep; 112(36):11282-7. PubMed ID: 26305952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Type II diabetes increases mitochondrial DNA mutations in the left ventricle of the Goto-Kakizaki diabetic rat.
    Hicks S; Labinskyy N; Piteo B; Laurent D; Mathew JE; Gupte SA; Edwards JG
    Am J Physiol Heart Circ Physiol; 2013 Apr; 304(7):H903-15. PubMed ID: 23376826
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.