174 related articles for article (PubMed ID: 31027708)
1. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
Fan X; He H; Li J; Luo G; Zheng Y; Zhou JK; He J; Pu W; Zhao Y
Bioorg Med Chem; 2019 Jun; 27(11):2235-2244. PubMed ID: 31027708
[TBL] [Abstract][Full Text] [Related]
2. Discovery of a Prenylated Flavonol Derivative as a Pin1 Inhibitor to Suppress Hepatocellular Carcinoma by Modulating MicroRNA Biogenesis.
Zheng Y; Pu W; Li J; Shen X; Zhou Q; Fan X; Yang SY; Yu Y; Chen Q; Wang C; Wu X; Peng Y
Chem Asian J; 2019 Jan; 14(1):130-134. PubMed ID: 30474357
[TBL] [Abstract][Full Text] [Related]
3. Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development.
Pu W; Li J; Zheng Y; Shen X; Fan X; Zhou JK; He J; Deng Y; Liu X; Wang C; Yang S; Chen Q; Liu L; Zhang G; Wei YQ; Peng Y
Hepatology; 2018 Aug; 68(2):547-560. PubMed ID: 29381806
[TBL] [Abstract][Full Text] [Related]
4. Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma.
Li J; Pu W; Sun HL; Zhou JK; Fan X; Zheng Y; He J; Liu X; Xia Z; Liu L; Wei YQ; Peng Y
Cell Death Differ; 2018 Sep; 25(9):1612-1624. PubMed ID: 29445125
[TBL] [Abstract][Full Text] [Related]
5. MicroRNA Biogenesis is Enhanced by Liposome-Encapsulated Pin1 Inhibitor in Hepatocellular Carcinoma.
Sun D; Tan S; Xiong Y; Pu W; Li J; Wei W; Huang C; Wei YQ; Peng Y
Theranostics; 2019; 9(16):4704-4716. PubMed ID: 31367251
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.
Zheng M; Xu H; Liao XH; Chen CP; Zhang AL; Lu W; Wang L; Yang D; Wang J; Liu H; Zhou XZ; Lu KP
Oncotarget; 2017 May; 8(18):29771-29784. PubMed ID: 28404959
[TBL] [Abstract][Full Text] [Related]
7. ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.
Sun HL; Cui R; Zhou J; Teng KY; Hsiao YH; Nakanishi K; Fassan M; Luo Z; Shi G; Tili E; Kutay H; Lovat F; Vicentini C; Huang HL; Wang SW; Kim T; Zanesi N; Jeon YJ; Lee TJ; Guh JH; Hung MC; Ghoshal K; Teng CM; Peng Y; Croce CM
Cancer Cell; 2016 Nov; 30(5):723-736. PubMed ID: 27846390
[TBL] [Abstract][Full Text] [Related]
8. The Role of Exportin-5 in MicroRNA Biogenesis and Cancer.
Wu K; He J; Pu W; Peng Y
Genomics Proteomics Bioinformatics; 2018 Apr; 16(2):120-126. PubMed ID: 29723684
[TBL] [Abstract][Full Text] [Related]
9. An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity.
Ieda N; Itoh K; Inoue Y; Izumiya Y; Kawaguchi M; Miyata N; Nakagawa H
Bioorg Med Chem Lett; 2019 Feb; 29(3):353-356. PubMed ID: 30585173
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and biological evaluation of benzimidazole derivatives as novel human Pin1 inhibitors.
Ma T; Huang M; Li A; Zhao F; Li D; Liu D; Zhao L
Bioorg Med Chem Lett; 2019 Jul; 29(14):1859-1863. PubMed ID: 31103446
[TBL] [Abstract][Full Text] [Related]
11. Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways.
Liao XH; Zhang AL; Zheng M; Li MQ; Chen CP; Xu H; Chu QS; Yang D; Lu W; Tsai TF; Liu H; Zhou XZ; Lu KP
Sci Rep; 2017 Mar; 7():43639. PubMed ID: 28262728
[TBL] [Abstract][Full Text] [Related]
12. Sustained and targeted delivery of siRNA/DP7-C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy.
Zhao B; Zhou B; Shi K; Zhang R; Dong C; Xie D; Tang L; Tian Y; Qian Z; Yang L
Cancer Sci; 2021 Jun; 112(6):2481-2492. PubMed ID: 33792132
[TBL] [Abstract][Full Text] [Related]
13. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).
Liu L; Zhu R; Li J; Pei Y; Wang S; Xu P; Wang M; Wen Y; Zhang H; Du D; Ding H; Jiang H; Chen K; Zhou B; Yu L; Luo C
J Med Chem; 2022 Feb; 65(3):2174-2190. PubMed ID: 35089030
[TBL] [Abstract][Full Text] [Related]
14. Identification of a potent and selective covalent Pin1 inhibitor.
Pinch BJ; Doctor ZM; Nabet B; Browne CM; Seo HS; Mohardt ML; Kozono S; Lian X; Manz TD; Chun Y; Kibe S; Zaidman D; Daitchman D; Yeoh ZC; Vangos NE; Geffken EA; Tan L; Ficarro SB; London N; Marto JA; Buratowski S; Dhe-Paganon S; Zhou XZ; Lu KP; Gray NS
Nat Chem Biol; 2020 Sep; 16(9):979-987. PubMed ID: 32483379
[TBL] [Abstract][Full Text] [Related]
15. miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression.
Leong KW; Cheng CW; Wong CM; Ng IO; Kwong YL; Tse E
Oncotarget; 2017 Feb; 8(7):11343-11355. PubMed ID: 28076852
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.
Cui G; Jin J; Chen H; Cao R; Chen X; Xu B
Bioorg Med Chem; 2018 May; 26(8):2186-2197. PubMed ID: 29576270
[TBL] [Abstract][Full Text] [Related]
17. MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways.
Yan X; Zhu Z; Xu S; Yang LN; Liao XH; Zheng M; Yang D; Wang J; Chen D; Wang L; Liu X; Liu J; Chen RH; Zhou XZ; Lu KP; Liu H
Sci Rep; 2017 Apr; 7():45915. PubMed ID: 28383568
[TBL] [Abstract][Full Text] [Related]
18. The role of Pin1 in the development and treatment of cancer.
Min SH; Zhou XZ; Lu KP
Arch Pharm Res; 2016 Dec; 39(12):1609-1620. PubMed ID: 27572155
[TBL] [Abstract][Full Text] [Related]
19. Dual Roles of Pin1 in Cancer Development and Progression.
Han HJ; Choi BY; Surh YJ
Curr Pharm Des; 2017 Nov; 23(29):4422-4425. PubMed ID: 28671058
[TBL] [Abstract][Full Text] [Related]
20. Pin1 inhibition reverses the acquired resistance of human hepatocellular carcinoma cells to Regorafenib via the Gli1/Snail/E-cadherin pathway.
Wang J; Zhang N; Han Q; Lu W; Wang L; Yang D; Zheng M; Zhang Z; Liu H; Lee TH; Zhou XZ; Lu KP
Cancer Lett; 2019 Mar; 444():82-93. PubMed ID: 30583078
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
