These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

416 related articles for article (PubMed ID: 31029706)

  • 1. Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure.
    Torres S; Baulies A; Insausti-Urkia N; Alarcón-Vila C; Fucho R; Solsona-Vilarrasa E; Núñez S; Robles D; Ribas V; Wakefield L; Grompe M; Lucena MI; Andrade RJ; Win S; Aung TA; Kaplowitz N; García-Ruiz C; Fernández-Checa JC
    Gastroenterology; 2019 Aug; 157(2):552-568. PubMed ID: 31029706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.
    Uzi D; Barda L; Scaiewicz V; Mills M; Mueller T; Gonzalez-Rodriguez A; Valverde AM; Iwawaki T; Nahmias Y; Xavier R; Chung RT; Tirosh B; Shibolet O
    J Hepatol; 2013 Sep; 59(3):495-503. PubMed ID: 23665281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.
    Cubero FJ; Zoubek ME; Hu W; Peng J; Zhao G; Nevzorova YA; Al Masaoudi M; Bechmann LP; Boekschoten MV; Muller M; Preisinger C; Gassler N; Canbay AE; Luedde T; Davis RJ; Liedtke C; Trautwein C
    Gastroenterology; 2016 Apr; 150(4):968-81. PubMed ID: 26708719
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress.
    Kusama H; Kon K; Ikejima K; Arai K; Aoyama T; Uchiyama A; Yamashina S; Watanabe S
    J Gastroenterol; 2017 May; 52(5):611-622. PubMed ID: 27599972
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
    Du K; Ramachandran A; Weemhoff JL; Chavan H; Xie Y; Krishnamurthy P; Jaeschke H
    Toxicol Sci; 2016 Dec; 154(2):214-226. PubMed ID: 27562556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes.
    Akakpo JY; Ramachandran A; Kandel SE; Ni HM; Kumer SC; Rumack BH; Jaeschke H
    Hum Exp Toxicol; 2018 Dec; 37(12):1310-1322. PubMed ID: 29739258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine.
    Akakpo JY; Ramachandran A; Rumack BH; Wallace DP; Jaeschke H
    Toxicology; 2023 Dec; 500():153692. PubMed ID: 38042273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.
    Bajt ML; Ramachandran A; Yan HM; Lebofsky M; Farhood A; Lemasters JJ; Jaeschke H
    Toxicol Sci; 2011 Aug; 122(2):598-605. PubMed ID: 21572097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.
    Xie Y; Ramachandran A; Breckenridge DG; Liles JT; Lebofsky M; Farhood A; Jaeschke H
    Toxicol Appl Pharmacol; 2015 Jul; 286(1):1-9. PubMed ID: 25818599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.
    Nguyen NT; Du K; Akakpo JY; Umbaugh DS; Jaeschke H; Ramachandran A
    Toxicol Lett; 2021 Mar; 338():21-31. PubMed ID: 33290831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis.
    Kim H; Lee JH; Park JW
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2333-2341. PubMed ID: 31121248
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
    Gunawan BK; Liu ZX; Han D; Hanawa N; Gaarde WA; Kaplowitz N
    Gastroenterology; 2006 Jul; 131(1):165-78. PubMed ID: 16831600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
    Conde de la Rosa L; Garcia-Ruiz C; Vallejo C; Baulies A; Nuñez S; Monte MJ; Marin JJG; Baila-Rueda L; Cenarro A; Civeira F; Fuster J; Garcia-Valdecasas JC; Ferrer J; Karin M; Ribas V; Fernandez-Checa JC
    J Hepatol; 2021 Jun; 74(6):1429-1441. PubMed ID: 33515644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mice deficient in pyruvate dehydrogenase kinase 4 are protected against acetaminophen-induced hepatotoxicity.
    Duan L; Ramachandran A; Akakpo JY; Woolbright BL; Zhang Y; Jaeschke H
    Toxicol Appl Pharmacol; 2020 Jan; 387():114849. PubMed ID: 31809757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice.
    Kim YH; Hwang JH; Kim KS; Noh JR; Choi DH; Kim DK; Tadi S; Yim YH; Choi HS; Lee CH
    J Hepatol; 2015 Jul; 63(1):75-82. PubMed ID: 25681557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.
    Xie Y; Williams CD; McGill MR; Lebofsky M; Ramachandran A; Jaeschke H
    Toxicol Sci; 2013 Jan; 131(1):325-35. PubMed ID: 22986947
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
    Shimizu D; Ishitsuka Y; Miyata K; Tomishima Y; Kondo Y; Irikura M; Iwawaki T; Oike Y; Irie T
    Pharmacol Res; 2014 Sep; 87():26-41. PubMed ID: 24951965
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.
    Xie Y; McGill MR; Du K; Dorko K; Kumer SC; Schmitt TM; Ding WX; Jaeschke H
    Toxicol Appl Pharmacol; 2015 Dec; 289(2):213-22. PubMed ID: 26431796
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbon monoxide ameliorates acetaminophen-induced liver injury by increasing hepatic HO-1 and Parkin expression.
    Chen Y; Park HJ; Park J; Song HC; Ryter SW; Surh YJ; Kim UH; Joe Y; Chung HT
    FASEB J; 2019 Dec; 33(12):13905-13919. PubMed ID: 31645120
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.
    Nakagawa H; Maeda S; Hikiba Y; Ohmae T; Shibata W; Yanai A; Sakamoto K; Ogura K; Noguchi T; Karin M; Ichijo H; Omata M
    Gastroenterology; 2008 Oct; 135(4):1311-21. PubMed ID: 18700144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.