BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

496 related articles for article (PubMed ID: 31034199)

  • 1. What Your Crystal Structure Will Not Tell You about Enzyme Function.
    Pochapsky TC; Pochapsky SS
    Acc Chem Res; 2019 May; 52(5):1409-1418. PubMed ID: 31034199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Some Surprising Implications of NMR-directed Simulations of Substrate Recognition and Binding by Cytochrome P450
    Asciutto EK; Pochapsky TC
    J Mol Biol; 2018 Apr; 430(9):1295-1310. PubMed ID: 29596916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate recognition by two different P450s: Evidence for conserved roles in a common fold.
    Tietz DR; Colthart AM; Sondej Pochapsky S; Pochapsky TC
    Sci Rep; 2017 Oct; 7(1):13581. PubMed ID: 29051575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Updating the Paradigm: Redox Partner Binding and Conformational Dynamics in Cytochromes P450.
    Poulos TL; Follmer AH
    Acc Chem Res; 2022 Feb; 55(3):373-380. PubMed ID: 34965086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Detection of substrate-dependent conformational changes in the P450 fold by nuclear magnetic resonance.
    Colthart AM; Tietz DR; Ni Y; Friedman JL; Dang M; Pochapsky TC
    Sci Rep; 2016 Feb; 6():22035. PubMed ID: 26911901
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Experimentally restrained molecular dynamics simulations for characterizing the open states of cytochrome P450cam.
    Asciutto EK; Dang M; Pochapsky SS; Madura JD; Pochapsky TC
    Biochemistry; 2011 Mar; 50(10):1664-71. PubMed ID: 21265500
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational selectivity in cytochrome P450 redox partner interactions.
    Hollingsworth SA; Batabyal D; Nguyen BD; Poulos TL
    Proc Natl Acad Sci U S A; 2016 Aug; 113(31):8723-8. PubMed ID: 27439869
    [TBL] [Abstract][Full Text] [Related]  

  • 8. How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.
    Lüdemann SK; Lounnas V; Wade RC
    J Mol Biol; 2000 Nov; 303(5):797-811. PubMed ID: 11061976
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
    Jóźwik IK; Kiss FM; Gricman Ł; Abdulmughni A; Brill E; Zapp J; Pleiss J; Bernhardt R; Thunnissen AW
    FEBS J; 2016 Nov; 283(22):4128-4148. PubMed ID: 27686671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformational plasticity and structure/function relationships in cytochromes P450.
    Pochapsky TC; Kazanis S; Dang M
    Antioxid Redox Signal; 2010 Oct; 13(8):1273-96. PubMed ID: 20446763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires.
    Hays AM; Dunn AR; Chiu R; Gray HB; Stout CD; Goodin DB
    J Mol Biol; 2004 Nov; 344(2):455-69. PubMed ID: 15522298
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.
    Tietz DR; Podust LM; Sherman DH; Pochapsky TC
    Biochemistry; 2017 May; 56(21):2701-2714. PubMed ID: 28488849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/uncoupling).
    Narasimhulu S
    Biochim Biophys Acta; 2007 Mar; 1770(3):360-75. PubMed ID: 17134838
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution structural ensembles of substrate-free cytochrome P450(cam).
    Asciutto EK; Young MJ; Madura J; Pochapsky SS; Pochapsky TC
    Biochemistry; 2012 Apr; 51(16):3383-93. PubMed ID: 22468842
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.
    Li S; Tietz DR; Rutaganira FU; Kells PM; Anzai Y; Kato F; Pochapsky TC; Sherman DH; Podust LM
    J Biol Chem; 2012 Nov; 287(45):37880-90. PubMed ID: 22952225
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enzyme dynamics from NMR spectroscopy.
    Palmer AG
    Acc Chem Res; 2015 Feb; 48(2):457-65. PubMed ID: 25574774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450-The Wonderful Nanomachine Revealed through Dynamic Simulations of the Catalytic Cycle.
    Dubey KD; Shaik S
    Acc Chem Res; 2019 Feb; 52(2):389-399. PubMed ID: 30633519
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate.
    Stoll S; Lee YT; Zhang M; Wilson RF; Britt RD; Goodin DB
    Proc Natl Acad Sci U S A; 2012 Aug; 109(32):12888-93. PubMed ID: 22826259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450cam: crystallography, oxygen activation, and electron transfer.
    Poulos TL; Raag R
    FASEB J; 1992 Jan; 6(2):674-9. PubMed ID: 1537455
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delicate conformational balance of the redox enzyme cytochrome P450cam.
    Skinner SP; Liu WM; Hiruma Y; Timmer M; Blok A; Hass MA; Ubbink M
    Proc Natl Acad Sci U S A; 2015 Jul; 112(29):9022-7. PubMed ID: 26130807
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.