These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. ASC specks exacerbate α‑synuclein pathology via amplifying NLRP3 inflammasome activities. Zheng R; Yan Y; Dai S; Ruan Y; Chen Y; Hu C; Lin Z; Xue N; Song Z; Liu Y; Zhang B; Pu J J Neuroinflammation; 2023 Feb; 20(1):26. PubMed ID: 36740674 [TBL] [Abstract][Full Text] [Related]
23. Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson's disease. Grotemeyer A; Fischer JF; Koprich JB; Brotchie JM; Blum R; Volkmann J; Ip CW J Neuroinflammation; 2023 Mar; 20(1):79. PubMed ID: 36945016 [TBL] [Abstract][Full Text] [Related]
24. RND3 modulates microglial polarization and alleviates neuroinflammation in Parkinson's disease by suppressing NLRP3 inflammasome activation. Hu W; Wang M; Sun G; Zhang L; Lu H Exp Cell Res; 2024 Jun; 439(1):114088. PubMed ID: 38744409 [TBL] [Abstract][Full Text] [Related]
25. From inflammasome to Parkinson's disease: Does the NLRP3 inflammasome facilitate exosome secretion and exosomal alpha-synuclein transmission in Parkinson's disease? Si XL; Fang YJ; Li LF; Gu LY; Yin XZ; Jun-Tian ; Yan YP; Pu JL; Zhang BR Exp Neurol; 2021 Feb; 336():113525. PubMed ID: 33161049 [TBL] [Abstract][Full Text] [Related]
26. PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway. Samidurai M; Palanisamy BN; Bargues-Carot A; Hepker M; Kondru N; Manne S; Zenitsky G; Jin H; Anantharam V; Kanthasamy AG; Kanthasamy A Front Aging Neurosci; 2021; 13():661505. PubMed ID: 34276337 [TBL] [Abstract][Full Text] [Related]
27. Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease. Haque ME; Akther M; Jakaria M; Kim IS; Azam S; Choi DK Mov Disord; 2020 Jan; 35(1):20-33. PubMed ID: 31680318 [TBL] [Abstract][Full Text] [Related]
28. Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment. Que R; Zheng J; Chang Z; Zhang W; Li H; Xie Z; Huang Z; Wang HT; Xu J; Jin D; Yang W; Tan EK; Wang Q Front Immunol; 2021; 12():794770. PubMed ID: 34925379 [TBL] [Abstract][Full Text] [Related]
29. Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease. Gordon R; Singh N; Lawana V; Ghosh A; Harischandra DS; Jin H; Hogan C; Sarkar S; Rokad D; Panicker N; Anantharam V; Kanthasamy AG; Kanthasamy A Neurobiol Dis; 2016 Sep; 93():96-114. PubMed ID: 27151770 [TBL] [Abstract][Full Text] [Related]
30. Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson's Disease Targeting Neuroinflammation. Chen CM; Yen CY; Chen WL; Lin CH; Wu YR; Chang KH; Lee-Chen GJ Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33494411 [TBL] [Abstract][Full Text] [Related]
32. HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production. Yu X; Lan P; Hou X; Han Q; Lu N; Li T; Jiao C; Zhang J; Zhang C; Tian Z J Hepatol; 2017 Apr; 66(4):693-702. PubMed ID: 28027970 [TBL] [Abstract][Full Text] [Related]
33. Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome. Shao A; Wu H; Hong Y; Tu S; Sun X; Wu Q; Zhao Q; Zhang J; Sheng J Mol Neurobiol; 2016 Jul; 53(5):3462-3476. PubMed ID: 26091790 [TBL] [Abstract][Full Text] [Related]
34. Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model. Hou L; Qu X; Qiu X; Huang R; Zhao X; Wang Q J Neuroinflammation; 2020 May; 17(1):148. PubMed ID: 32375810 [TBL] [Abstract][Full Text] [Related]
35. Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells. Lee CM; Lee DS; Jung WK; Yoo JS; Yim MJ; Choi YH; Park S; Seo SK; Choi JS; Lee YM; Park WS; Choi IW Int J Mol Med; 2016 Sep; 38(3):912-8. PubMed ID: 27430883 [TBL] [Abstract][Full Text] [Related]
36. CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys. Hou Y; Wang Q; Han B; Chen Y; Qiao X; Wang L Cell Death Dis; 2021 May; 12(6):523. PubMed ID: 34021126 [TBL] [Abstract][Full Text] [Related]
37. Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of parkin-mediated mitophagy in in-vitro and in-vivo models of Parkinson disease. Ahmed S; Kwatra M; Ranjan Panda S; Murty USN; Naidu VGM Brain Behav Immun; 2021 Jan; 91():142-158. PubMed ID: 32971182 [TBL] [Abstract][Full Text] [Related]
38. Role of α-synuclein in microglia: autophagy and phagocytosis balance neuroinflammation in Parkinson's disease. Lv QK; Tao KX; Wang XB; Yao XY; Pang MZ; Liu JY; Wang F; Liu CF Inflamm Res; 2023 Mar; 72(3):443-462. PubMed ID: 36598534 [TBL] [Abstract][Full Text] [Related]
39. Edaravone Attenuates the Proinflammatory Response in Amyloid-β-Treated Microglia by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion. Wang HM; Zhang T; Huang JK; Xiang JY; Chen JJ; Fu JL; Zhao YW Cell Physiol Biochem; 2017; 43(3):1113-1125. PubMed ID: 28977782 [TBL] [Abstract][Full Text] [Related]