BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 31047751)

  • 1. Design, synthesis and biological evaluation of novel antitumor spirodihydrothiopyran-oxindole derivatives.
    Liu W; Chen S; Zhang F; He S; Wang S; Sheng C
    Bioorg Med Chem Lett; 2019 Jul; 29(13):1636-1642. PubMed ID: 31047751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of spiro-tetrahydrothiopyran-oxindoles by Michael-aldol cascade reactions: discovery of potential P53-MDM2 inhibitors with good antitumor activity.
    Wang S; Chen S; Guo Z; He S; Zhang F; Liu X; Chen W; Zhang S; Sheng C
    Org Biomol Chem; 2018 Jan; 16(4):625-634. PubMed ID: 29302672
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.
    Gupta AK; Bharadwaj M; Kumar A; Mehrotra R
    Top Curr Chem (Cham); 2017 Feb; 375(1):3. PubMed ID: 27943171
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of novel antitumor spirotetrahydrothiopyran-oxindole derivatives as potent p53-MDM2 inhibitors.
    Ji C; Wang S; Chen S; He S; Jiang Y; Miao Z; Li J; Sheng C
    Bioorg Med Chem; 2017 Oct; 25(20):5268-5277. PubMed ID: 28797774
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis and Antitumor Activity of Novel Dispiro[oxindole-cyclohexanone]- pyrrolidines.
    Gouda M; Bawazeer M; Hegazy L; Azab M; Elagawany M; Rateb M; Yaseen M; Elgendy B
    Curr Pharm Des; 2022; 28(3):198-207. PubMed ID: 34176458
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents.
    Al-Majid AM; Ali M; Islam MS; Alshahrani S; Alamary AS; Yousuf S; Choudhary MI; Barakat A
    Molecules; 2021 Oct; 26(20):. PubMed ID: 34684885
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation.
    Liu SJ; Zhao Q; Peng C; Mao Q; Wu F; Zhang FH; Feng QS; He G; Han B
    Eur J Med Chem; 2021 May; 217():113359. PubMed ID: 33725632
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies on the Enantioselective Synthesis of
    Yayik N; Pérez M; Molins E; Bosch J; Amat M
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33467493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA Fragmentation, Cell Cycle Arrest, and Docking Study of Novel Bis Spiro-cyclic 2-oxindole of Pyrimido[4,5-b]quinoline-4,6-dione Derivatives Against Breast Carcinoma.
    Mohamed MF; Abdelmoniem AM; Elwahy AHM; Abdelhamid IA
    Curr Cancer Drug Targets; 2018; 18(4):372-381. PubMed ID: 28669339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of new thiazolo-pyrrolidine-(spirooxindole) tethered to 3-acylindole as anticancer agents.
    Islam MS; Ghawas HM; El-Senduny FF; Al-Majid AM; Elshaier YAMM; Badria FA; Barakat A
    Bioorg Chem; 2019 Feb; 82():423-430. PubMed ID: 30508794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.
    Nunes RC; Ribeiro CJA; Monteiro Â; Rodrigues CMP; Amaral JD; Santos MMM
    Eur J Med Chem; 2017 Oct; 139():168-179. PubMed ID: 28800455
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Organocatalytic Asymmetric Synthesis of Spiro-oxindole Piperidine Derivatives That Reduce Cancer Cell Proliferation by Inhibiting MDM2-p53 Interaction.
    Yang MC; Peng C; Huang H; Yang L; He XH; Huang W; Cui HL; He G; Han B
    Org Lett; 2017 Dec; 19(24):6752-6755. PubMed ID: 29210587
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of p53-Murine Double Minute 2 (MDM2) Interactions with 3,3'-Spirocyclopentene Oxindole Derivatives.
    Gicquel M; Gomez C; Garcia Alvarez MC; Pamlard O; Guérineau V; Jacquet E; Bignon J; Voituriez A; Marinetti A
    J Med Chem; 2018 Oct; 61(20):9386-9392. PubMed ID: 30221935
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereocontrolled [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes to Iminooxindoles: Access to Spiro[oxindole-3,2'-pyrrolidines].
    Akaev AA; Bezzubov SI; Desyatkin VG; Vorobyeva NS; Majouga AG; Melnikov MY; Budynina EM
    J Org Chem; 2019 Mar; 84(6):3340-3356. PubMed ID: 30735387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fe
    Maddela S; Makula A; Galigniana MD; Parambi DGT; Federicci F; Mazaira G; Hendawy OM; Dev S; Mathew GE; Mathew B
    Arch Pharm (Weinheim); 2019 Jan; 352(1):e1800174. PubMed ID: 30485473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.
    Rodriguez KX; Howe EN; Bacher EP; Burnette M; Meloche JL; Meisel J; Schnepp P; Tan X; Chang M; Zartman J; Zhang S; Ashfeld BL
    ChemMedChem; 2019 Sep; 14(18):1653-1661. PubMed ID: 31140738
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An overview of spirooxindole as a promising scaffold for novel drug discovery.
    Zhou LM; Qu RY; Yang GF
    Expert Opin Drug Discov; 2020 May; 15(5):603-625. PubMed ID: 32106717
    [No Abstract]   [Full Text] [Related]  

  • 18. A water mediated multicomponent reaction for the synthesis of novel spirooxindole derivatives and their antifungal activity.
    Zhang M; Shi L; Chen L; Liu Z; Zhao T; Zhu C; Yang L
    Org Biomol Chem; 2024 May; 22(17):3459-3467. PubMed ID: 38597668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of new LXRβ agonists as glioblastoma inhibitors.
    Chen H; Chen Z; Zhang Z; Li Y; Zhang S; Jiang F; Wei J; Ding P; Zhou H; Gu Q; Xu J
    Eur J Med Chem; 2020 May; 194():112240. PubMed ID: 32248003
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of 3,3'-pyrrolidinyl-spirooxindoles as cardioprotectant prohibitin ligands.
    Elderwish S; Audebrand A; Nebigil CG; Désaubry L
    Eur J Med Chem; 2020 Jan; 186():111859. PubMed ID: 31735574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.