These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 31050000)

  • 1. Evaluation of Weight Thresholds for Pediatric Patients to Use Adult Dosage of Therapeutic Monoclonal Antibodies.
    Yang N; Xu MC; Yao Z
    J Clin Pharmacol; 2019 Oct; 59(10):1309-1318. PubMed ID: 31050000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Model-Aided Adults-to-Children Pharmacokinetic Extrapolation and Empirical Body Size-Based Dosing Exploration for Therapeutic Monoclonal Antibodies-Is Allometry a Reasonable Choice?
    Xu Y; Langevin BA; Zhou H; Xu Z
    J Clin Pharmacol; 2020 Dec; 60(12):1573-1584. PubMed ID: 32578225
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A guide to rational dosing of monoclonal antibodies.
    Bai S; Jorga K; Xin Y; Jin D; Zheng Y; Damico-Beyer LA; Gupta M; Tang M; Allison DE; Lu D; Zhang Y; Joshi A; Dresser MJ
    Clin Pharmacokinet; 2012 Feb; 51(2):119-35. PubMed ID: 22257150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey and hFcRn Tg32 transgenic mouse using a population-modeling approach.
    Betts A; Keunecke A; van Steeg TJ; van der Graaf PH; Avery LB; Jones H; Berkhout J
    MAbs; 2018 Jul; 10(5):751-764. PubMed ID: 29634430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trials.
    Fasanmade AA; Adedokun OJ; Blank M; Zhou H; Davis HM
    Clin Ther; 2011 Jul; 33(7):946-64. PubMed ID: 21741088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Monoclonal Antibodies and Fc-Fusion Proteins for Pediatric Use: Dosing, Immunogenicity, and Modeling and Simulation in Data Submitted to the US Food and Drug Administration.
    Liu XI; Dallmann A; Wang YM; Green DJ; Burnham JM; Chiang B; Wu P; Sheng M; Lu K; van den Anker JN; Burckart GJ
    J Clin Pharmacol; 2019 Aug; 59(8):1130-1143. PubMed ID: 30865317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of drug clearance in children: impact of allometric exponents, body weight, and age.
    Mahmood I
    Ther Drug Monit; 2007 Jun; 29(3):271-8. PubMed ID: 17529882
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fixed dosing versus body size-based dosing of monoclonal antibodies in adult clinical trials.
    Wang DD; Zhang S; Zhao H; Men AY; Parivar K
    J Clin Pharmacol; 2009 Sep; 49(9):1012-24. PubMed ID: 19620385
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pediatric Dose Selection for Therapeutic Proteins.
    Malik PRV; Temrikar ZH; Chelle P; Edginton AN; Meibohm B
    J Clin Pharmacol; 2021 Jun; 61 Suppl 1():S193-S206. PubMed ID: 34185910
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of dosing strategy for pembrolizumab for oncology indications.
    Freshwater T; Kondic A; Ahamadi M; Li CH; de Greef R; de Alwis D; Stone JA
    J Immunother Cancer; 2017; 5():43. PubMed ID: 28515943
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adolescent dosing and labeling since the Food and Drug Administration Amendments Act of 2007.
    Momper JD; Mulugeta Y; Green DJ; Karesh A; Krudys KM; Sachs HC; Yao LP; Burckart GJ
    JAMA Pediatr; 2013 Oct; 167(10):926-32. PubMed ID: 23921678
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pediatric physiology in relation to the pharmacokinetics of monoclonal antibodies.
    Malik P; Edginton A
    Expert Opin Drug Metab Toxicol; 2018 Jun; 14(6):585-599. PubMed ID: 29806953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Population pharmacokinetics of therapeutic monoclonal antibodies.
    Dirks NL; Meibohm B
    Clin Pharmacokinet; 2010 Oct; 49(10):633-59. PubMed ID: 20818831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allometry Is a Reasonable Choice in Pediatric Drug Development.
    Liu T; Ghafoori P; Gobburu JV
    J Clin Pharmacol; 2017 Apr; 57(4):469-475. PubMed ID: 27649629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allometric Scaling of Therapeutic Monoclonal Antibodies Using Antigen Concentration as a Correction Factor: Application to the Human Clearance Prediction.
    Wang L; Qiang W; Cheng Z
    J Pharm Sci; 2016 Mar; 105(3):1335-40. PubMed ID: 26886347
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients.
    Temrikar ZH; Suryawanshi S; Meibohm B
    Paediatr Drugs; 2020 Apr; 22(2):199-216. PubMed ID: 32052309
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Challenges and considerations for development of therapeutic proteins in pediatric patients.
    Zhang Y; Wei X; Bajaj G; Barrett JS; Meibohm B; Joshi A; Gupta M
    J Clin Pharmacol; 2015 Mar; 55 Suppl 3():S103-15. PubMed ID: 25707958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.
    Ge S; Mendley SR; Gerhart JG; Melloni C; Hornik CP; Sullivan JE; Atz A; Delmore P; Tremoulet A; Harper B; Payne E; Lin S; Erinjeri J; Cohen-Wolkowiez M; Gonzalez D;
    Clin Transl Sci; 2020 Nov; 13(6):1189-1198. PubMed ID: 32324313
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Population Pharmacokinetics and Exposure-Response Modeling Analyses of Golimumab in Children With Moderately to Severely Active Ulcerative Colitis.
    Xu Y; Adedokun OJ; Chan D; Hu C; Xu Z; Strauss RS; Hyams JS; Turner D; Zhou H
    J Clin Pharmacol; 2019 Apr; 59(4):590-604. PubMed ID: 30536638
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assessment of Ketamine Adult Anesthetic Doses in Pediatrics Using Pharmacokinetic Modeling and Simulations.
    Elkomy MH; Alruwaili N; Elmowafy M; Shalaby K; Drover DR; Ramamoorthy C
    Pharmacotherapy; 2019 Apr; 39(4):454-462. PubMed ID: 30825333
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.