These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 31050027)

  • 1. Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent.
    Nuthakki VK; Sharma A; Kumar A; Bharate SB
    Drug Dev Res; 2019 Aug; 80(5):655-665. PubMed ID: 31050027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones.
    Lee S; Youn K; Lim G; Lee J; Jun M
    Molecules; 2018 Jun; 23(7):. PubMed ID: 29932100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity.
    Nuthakki VK; Yadav Bheemanaboina RR; Bharate SB
    Bioorg Chem; 2021 Feb; 107():104568. PubMed ID: 33418314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability.
    Jannat S; Balupuri A; Ali MY; Hong SS; Choi CW; Choi YH; Ku JM; Kim WJ; Leem JY; Kim JE; Shrestha AC; Ham HN; Lee KH; Kim DM; Kang NS; Park GH
    Exp Mol Med; 2019 Feb; 51(2):1-18. PubMed ID: 30755593
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural determinants of the multifunctional profile of dual binding site acetylcholinesterase inhibitors as anti-Alzheimer agents.
    Galdeano C; Viayna E; Arroyo P; Bidon-Chanal A; Blas JR; Muñoz-Torrero D; Luque FJ
    Curr Pharm Des; 2010; 16(25):2818-36. PubMed ID: 20698824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of dual inhibitors against Alzheimer's disease using fragment-based QSAR and molecular docking.
    Goyal M; Dhanjal JK; Goyal S; Tyagi C; Hamid R; Grover A
    Biomed Res Int; 2014; 2014():979606. PubMed ID: 25019089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors.
    Nuthakki VK; Mudududdla R; Sharma A; Kumar A; Bharate SB
    Bioorg Chem; 2019 Sep; 90():103062. PubMed ID: 31220673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and molecular docking study of fish roe-derived peptides as potent BACE 1, AChE, and BChE inhibitors.
    Yu Z; Ji H; Shen J; Kan R; Zhao W; Li J; Ding L; Liu J
    Food Funct; 2020 Jul; 11(7):6643-6651. PubMed ID: 32656560
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448.
    Nuthakki VK; Choudhary S; Reddy CN; Bhatt S; Jamwal A; Jotshi A; Raghuvanshi R; Sharma A; Thakur S; Jadhav HR; Bharate SS; Nandi U; Kumar A; Bharate SB
    ACS Chem Neurosci; 2023 Mar; 14(6):1193-1219. PubMed ID: 36812360
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides.
    Choi RJ; Roy A; Jung HJ; Ali MY; Min BS; Park CH; Yokozawa T; Fan TP; Choi JS; Jung HA
    J Ethnopharmacol; 2016 Aug; 190():219-30. PubMed ID: 27275774
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative Evaluation of the Antioxidant and Anti-Alzheimer's Disease Potential of Coumestrol and Puerarol Isolated from Pueraria lobata Using Molecular Modeling Studies.
    Koirala P; Seong SH; Jung HA; Choi JS
    Molecules; 2018 Mar; 23(4):. PubMed ID: 29597336
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway.
    Ali MY; Jannat S; Edraki N; Das S; Chang WK; Kim HC; Park SK; Chang MS
    Chem Biol Interact; 2019 Aug; 309():108707. PubMed ID: 31194956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases.
    Jung HA; Ali MY; Jung HJ; Jeong HO; Chung HY; Choi JS
    J Ethnopharmacol; 2016 Sep; 191():152-160. PubMed ID: 27321278
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of potential inhibitors of cholinergic and β-secretase enzymes from phytochemicals derived from Gongronema latifolium Benth leaf: an integrated computational analysis.
    Gyebi GA; Ogunyemi OM; Ibrahim IM; Ogunro OB; Afolabi SO; Ojo RJ; Anyanwu GO; El-Saber Batiha G; Adebayo JO
    Mol Divers; 2024 Jun; 28(3):1305-1322. PubMed ID: 37338673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multitargeted C9-substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics.
    Raghuvanshi R; Jamwal A; Nandi U; Bharate SB
    Drug Dev Res; 2023 Feb; 84(1):121-140. PubMed ID: 36461610
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation of cholinesterase and β-secretase 1 inhibiting compounds from Lycopodiella cernua.
    Nguyen VT; To DC; Tran MH; Oh SH; Kim JA; Ali MY; Woo MH; Choi JS; Min BS
    Bioorg Med Chem; 2015 Jul; 23(13):3126-34. PubMed ID: 26003344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches.
    Han J; Ji Y; Youn K; Lim G; Lee J; Kim DH; Jun M
    Nutrients; 2019 Nov; 11(11):. PubMed ID: 31703329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetics and molecular docking of dihydroxanthyletin-type coumarins from Angelica decursiva that inhibit cholinesterase and BACE1.
    Ali MY; Seong SH; Jung HA; Jannat S; Choi JS
    Arch Pharm Res; 2018 Jul; 41(7):753-764. PubMed ID: 30047040
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-Alzheimer's disease activity of compounds from the root bark of Morus alba L.
    Kuk EB; Jo AR; Oh SI; Sohn HS; Seong SH; Roy A; Choi JS; Jung HA
    Arch Pharm Res; 2017 Mar; 40(3):338-349. PubMed ID: 28093699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz.
    Raghuvanshi R; Nuthakki VK; Singh L; Singh B; Bharate SS; Bhatti R; Bharate SB
    Phytomedicine; 2021 Oct; 91():153659. PubMed ID: 34332286
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.