177 related articles for article (PubMed ID: 31053140)
1. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production.
Newman M; Hin N; Pederson S; Lardelli M
Mol Brain; 2019 May; 12(1):43. PubMed ID: 31053140
[TBL] [Abstract][Full Text] [Related]
2. Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer's disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis.
Dong Y; Newman M; Pederson SM; Barthelson K; Hin N; Lardelli M
BMC Genomics; 2021 Mar; 22(1):211. PubMed ID: 33761877
[TBL] [Abstract][Full Text] [Related]
3. Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer's disease.
Barthelson K; Pederson SM; Newman M; Lardelli M
Mol Brain; 2020 Oct; 13(1):142. PubMed ID: 33076949
[TBL] [Abstract][Full Text] [Related]
4. The Use of Zebrafish in Transcriptome Analysis of the Early Effects of Mutations Causing Early Onset Familial Alzheimer's Disease and Other Inherited Neurodegenerative Conditions.
Lardelli M; Baer L; Hin N; Allen A; Pederson SM; Barthelson K
J Alzheimers Dis; 2024; 99(s2):S367-S381. PubMed ID: 37742650
[TBL] [Abstract][Full Text] [Related]
5. PRESENILIN 1 Mutations Causing Early-Onset Familial Alzheimer's Disease or Familial Acne Inversa Differ in Their Effects on Genes Facilitating Energy Metabolism and Signal Transduction.
Barthelson K; Dong Y; Newman M; Lardelli M
J Alzheimers Dis; 2021; 82(1):327-347. PubMed ID: 34024832
[TBL] [Abstract][Full Text] [Related]
6. Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2.
Hin N; Newman M; Kaslin J; Douek AM; Lumsden A; Nik SHM; Dong Y; Zhou XF; Mañucat-Tan NB; Ludington A; Adelson DL; Pederson S; Lardelli M
PLoS One; 2020; 15(1):e0227258. PubMed ID: 31978074
[TBL] [Abstract][Full Text] [Related]
7. Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of presenilin 1.
Newman M; Nik HM; Sutherland GT; Hin N; Kim WS; Halliday GM; Jayadev S; Smith C; Laird AS; Lucas CW; Kittipassorn T; Peet DJ; Lardelli M
Hum Mol Genet; 2020 Aug; 29(14):2379-2394. PubMed ID: 32588886
[TBL] [Abstract][Full Text] [Related]
8. Brain Transcriptome Analysis of a Protein-Truncating Mutation in Sortilin-Related Receptor 1 Associated With Early-Onset Familial Alzheimer's Disease Indicates Early Effects on Mitochondrial and Ribosome Function.
Barthelson K; Pederson SM; Newman M; Lardelli M
J Alzheimers Dis; 2021; 79(3):1105-1119. PubMed ID: 33386808
[TBL] [Abstract][Full Text] [Related]
9. No observed effect on brain vasculature of Alzheimer's disease-related mutations in the zebrafish presenilin 1 gene.
Barthelson K; Newman M; Nowell CJ; Lardelli M
Mol Brain; 2021 Jan; 14(1):22. PubMed ID: 33494778
[TBL] [Abstract][Full Text] [Related]
10. Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity.
Nornes S; Newman M; Verdile G; Wells S; Stoick-Cooper CL; Tucker B; Frederich-Sleptsova I; Martins R; Lardelli M
Hum Mol Genet; 2008 Feb; 17(3):402-12. PubMed ID: 17981814
[TBL] [Abstract][Full Text] [Related]
11. Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2.
Jiang H; Pederson SM; Newman M; Dong Y; Barthelson K; Lardelli M
PLoS One; 2020; 15(7):e0232559. PubMed ID: 32658922
[TBL] [Abstract][Full Text] [Related]
12. Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism.
Barthelson K; Newman M; Lardelli M
Dis Model Mech; 2022 Jan; 15(1):. PubMed ID: 34842276
[TBL] [Abstract][Full Text] [Related]
13. Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity.
Moussavi Nik SH; Newman M; Wilson L; Ebrahimie E; Wells S; Musgrave I; Verdile G; Martins RN; Lardelli M
Hum Mol Genet; 2015 Jul; 24(13):3662-78. PubMed ID: 25814654
[TBL] [Abstract][Full Text] [Related]
14. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress.
Ebrahimie E; Moussavi Nik SH; Newman M; Van Der Hoek M; Lardelli M
J Alzheimers Dis; 2016 Mar; 52(2):581-608. PubMed ID: 27031468
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate.
Dixit S; Fessel JP; Harrison FE
Free Radic Biol Med; 2017 Nov; 112():515-523. PubMed ID: 28863942
[TBL] [Abstract][Full Text] [Related]
16. Mutational analysis in early-onset familial Alzheimer's disease in Mainland China.
Jiao B; Tang B; Liu X; Xu J; Wang Y; Zhou L; Zhang F; Yan X; Zhou Y; Shen L
Neurobiol Aging; 2014 Aug; 35(8):1957.e1-6. PubMed ID: 24650794
[TBL] [Abstract][Full Text] [Related]
17. Presenilin-1 Targeted Morpholino Induces Cognitive Deficits, Increased Brain Aβ
Nery LR; Silva NE; Fonseca R; Vianna MRM
Neurochem Res; 2017 Oct; 42(10):2959-2967. PubMed ID: 28623607
[TBL] [Abstract][Full Text] [Related]
18. Early-onset familial Alzheimer's disease (EOFAD).
Wu L; Rosa-Neto P; Hsiung GY; Sadovnick AD; Masellis M; Black SE; Jia J; Gauthier S
Can J Neurol Sci; 2012 Jul; 39(4):436-45. PubMed ID: 22728850
[TBL] [Abstract][Full Text] [Related]
19. A novel presenilin 1 mutation (Ser169del) in a Chinese family with early-onset Alzheimer's disease.
Guo J; Wei J; Liao S; Wang L; Jiang H; Tang B
Neurosci Lett; 2010 Jan; 468(1):34-7. PubMed ID: 19853643
[TBL] [Abstract][Full Text] [Related]
20. Clinical characterization of a presenilin 1 mutation (F177S) in a family with very early-onset Alzheimer's disease in the third decade of life.
Hausner L; Tschäpe JA; Schmitt HP; Hentschel F; Hartmann T; Frölich L
Alzheimers Dement; 2014 Mar; 10(2):e27-39. PubMed ID: 23850332
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
