BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 31060243)

  • 1. Functional Characterization of Colon Cancer-Associated Mutations in
    Pavlenko E; Cabron AS; Arnold P; Dobert JP; Rose-John S; Zunke F
    Int J Mol Sci; 2019 May; 20(9):. PubMed ID: 31060243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
    Schwarz J; Broder C; Helmstetter A; Schmidt S; Yan I; Müller M; Schmidt-Arras D; Becker-Pauly C; Koch-Nolte F; Mittrücker HW; Rabe B; Rose-John S; Chalaris A
    Biochim Biophys Acta; 2013 Dec; 1833(12):3355-3367. PubMed ID: 24135057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
    Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
    J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
    Düsterhöft S; Kahveci-Türköz S; Wozniak J; Seifert A; Kasparek P; Ohm H; Liu S; Kopkanova J; Lokau J; Garbers C; Preisinger C; Sedlacek R; Freeman M; Ludwig A
    Cell Mol Life Sci; 2021 Jun; 78(11):5015-5040. PubMed ID: 33950315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.
    Mustafi R; Dougherty U; Mustafi D; Ayaloglu-Butun F; Fletcher M; Adhikari S; Sadiq F; Meckel K; Haider HI; Khalil A; Pekow J; Konda V; Joseph L; Hart J; Fichera A; Li YC; Bissonnette M
    Clin Cancer Res; 2017 Jan; 23(2):549-561. PubMed ID: 27489286
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
    Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
    FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.
    Park GB; Kim D
    Mol Cell Biochem; 2017 Jan; 425(1-2):191-202. PubMed ID: 27837433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
    Lora J; Weskamp G; Li TM; Maretzky T; Shola DTN; Monette S; Lichtenthaler SF; Lu TT; Yang C; Blobel CP
    J Biol Chem; 2021; 296():100733. PubMed ID: 33957124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway.
    Shi W; Men L; Pi X; Jiang T; Peng D; Huo S; Luo P; Wang M; Guo J; Jiang Y; Peng L; Lin L; Li S; Lv J
    Int J Oncol; 2021 Dec; 59(6):. PubMed ID: 34726248
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.
    Groth E; Pruessmeyer J; Babendreyer A; Schumacher J; Pasqualon T; Dreymueller D; Higashiyama S; Lorenzen I; Grötzinger J; Cataldo D; Ludwig A
    Biochim Biophys Acta; 2016 Nov; 1863(11):2795-2808. PubMed ID: 27599715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular switch in human diseases-disintegrin and metalloproteinases, ADAM17.
    Yang G; Cui M; Jiang W; Sheng J; Yang Y; Zhang X
    Aging (Albany NY); 2021 Jun; 13(12):16859-16872. PubMed ID: 34182543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distance dependent shedding of IL-6R.
    Düsterhöft S; Bartels AK; Koudelka T; Lilienthal E; Schäfer M; Garbers C; Tholey A; Grötzinger J; Lorenzen I
    Biochem Biophys Res Commun; 2020 May; 526(2):355-360. PubMed ID: 32222277
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
    Park GB; Kim D
    Mol Cell Biochem; 2018 Feb; 439(1-2):199-211. PubMed ID: 28819788
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer.
    Elahi A; Ajidahun A; Hendrick L; Getun I; Humphries LA; Hernandez J; Shibata D
    J Surg Res; 2020 Oct; 254():183-190. PubMed ID: 32450419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rare mutations of
    Xie Y; Ma A; Wang B; Peng R; Jing Y; Wang D; Finnell RH; Qiao B; Wang Y; Wang H; Zheng Y
    Clin Sci (Lond); 2019 Jan; 133(2):225-238. PubMed ID: 30610007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
    Riethmueller S; Ehlers JC; Lokau J; Düsterhöft S; Knittler K; Dombrowsky G; Grötzinger J; Rabe B; Rose-John S; Garbers C
    Sci Rep; 2016 May; 6():25550. PubMed ID: 27151651
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The shedding protease ADAM17: Physiology and pathophysiology.
    Zunke F; Rose-John S
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2059-2070. PubMed ID: 28705384
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ADAM17 orchestrates Interleukin-6, TNFα and EGF-R signaling in inflammation and cancer.
    Schumacher N; Rose-John S
    Biochim Biophys Acta Mol Cell Res; 2022 Jan; 1869(1):119141. PubMed ID: 34610348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Status update on iRhom and ADAM17: It's still complicated.
    Düsterhöft S; Babendreyer A; Giese AA; Flasshove C; Ludwig A
    Biochim Biophys Acta Mol Cell Res; 2019 Oct; 1866(10):1567-1583. PubMed ID: 31330158
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
    Shimoda M; Horiuchi K; Sasaki A; Tsukamoto T; Okabayashi K; Hasegawa H; Kitagawa Y; Okada Y
    EBioMedicine; 2016 Mar; 5():114-24. PubMed ID: 27077118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.