BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

397 related articles for article (PubMed ID: 31067297)

  • 1. PAX7 target gene repression is a superior FSHD biomarker than DUX4 target gene activation, associating with pathological severity and identifying FSHD at the single-cell level.
    Banerji CRS; Zammit PS
    Hum Mol Genet; 2019 Jul; 28(13):2224-2236. PubMed ID: 31067297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PAX7 target gene repression associates with FSHD progression and pathology over 1 year.
    Banerji CRS
    Hum Mol Genet; 2020 Aug; 29(13):2124-2133. PubMed ID: 32347924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.
    Banerji CRS; Panamarova M; Hebaishi H; White RB; Relaix F; Severini S; Zammit PS
    Nat Commun; 2017 Dec; 8(1):2152. PubMed ID: 29255294
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pathomechanisms and biomarkers in facioscapulohumeral muscular dystrophy: roles of DUX4 and PAX7.
    Banerji CRS; Zammit PS
    EMBO Mol Med; 2021 Aug; 13(8):e13695. PubMed ID: 34151531
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures.
    Haynes P; Kernan K; Zhou SL; Miller DG
    Skelet Muscle; 2017 Jun; 7(1):13. PubMed ID: 28637492
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Facioscapulohumeral dystrophy transcriptome signatures correlate with different stages of disease and are marked by different MRI biomarkers.
    van den Heuvel A; Lassche S; Mul K; Greco A; San León Granado D; Heerschap A; Küsters B; Tapscott SJ; Voermans NC; van Engelen BGM; van der Maarel SM
    Sci Rep; 2022 Jan; 12(1):1426. PubMed ID: 35082321
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele.
    Haynes P; Bomsztyk K; Miller DG
    Epigenetics Chromatin; 2018 Aug; 11(1):47. PubMed ID: 30122154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The FSHD muscle-blood biomarker: a circulating transcriptomic biomarker for clinical severity in facioscapulohumeral muscular dystrophy.
    Banerji CRS; Greco A; Joosten LAB; van Engelen BGM; Zammit PS
    Brain Commun; 2023; 5(5):fcad221. PubMed ID: 37731904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle.
    Yao Z; Snider L; Balog J; Lemmers RJ; Van Der Maarel SM; Tawil R; Tapscott SJ
    Hum Mol Genet; 2014 Oct; 23(20):5342-52. PubMed ID: 24861551
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development.
    van den Heuvel A; Mahfouz A; Kloet SL; Balog J; van Engelen BGM; Tawil R; Tapscott SJ; van der Maarel SM
    Hum Mol Genet; 2019 Apr; 28(7):1064-1075. PubMed ID: 30445587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DUX4 expressing immortalized FSHD lymphoblastoid cells express genes elevated in FSHD muscle biopsies, correlating with the early stages of inflammation.
    Banerji CRS; Panamarova M; Zammit PS
    Hum Mol Genet; 2020 Aug; 29(14):2285-2299. PubMed ID: 32242220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Facioscapulohumeral muscular dystrophy family studies of DUX4 expression: evidence for disease modifiers and a quantitative model of pathogenesis.
    Jones TI; Chen JC; Rahimov F; Homma S; Arashiro P; Beermann ML; King OD; Miller JB; Kunkel LM; Emerson CP; Wagner KR; Jones PL
    Hum Mol Genet; 2012 Oct; 21(20):4419-30. PubMed ID: 22798623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of
    Duranti E; Villa C
    Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A complex interplay of genetic and epigenetic events leads to abnormal expression of the DUX4 gene in facioscapulohumeral muscular dystrophy.
    Gatica LV; Rosa AL
    Neuromuscul Disord; 2016 Dec; 26(12):844-852. PubMed ID: 27816329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD.
    Wang LH; Friedman SD; Shaw D; Snider L; Wong CJ; Budech CB; Poliachik SL; Gove NE; Lewis LM; Campbell AE; Lemmers RJFL; Maarel SM; Tapscott SJ; Tawil RN
    Hum Mol Genet; 2019 Feb; 28(3):476-486. PubMed ID: 30312408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DUX4 expression in FSHD muscle cells: how could such a rare protein cause a myopathy?
    Tassin A; Laoudj-Chenivesse D; Vanderplanck C; Barro M; Charron S; Ansseau E; Chen YW; Mercier J; Coppée F; Belayew A
    J Cell Mol Med; 2013 Jan; 17(1):76-89. PubMed ID: 23206257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy.
    Cowley MV; Pruller J; Ganassi M; Zammit PS; Banerji CRS
    Elife; 2023 May; 12():. PubMed ID: 37184373
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Facioscapulohumeral muscular dystrophy: molecular pathological advances and future directions.
    Statland JM; Tawil R
    Curr Opin Neurol; 2011 Oct; 24(5):423-8. PubMed ID: 21734574
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of the double homeodomain protein DUX4c interferes with myofibrillogenesis and induces clustering of myonuclei.
    Vanderplanck C; Tassin A; Ansseau E; Charron S; Wauters A; Lancelot C; Vancutsem K; Laoudj-Chenivesse D; Belayew A; Coppée F
    Skelet Muscle; 2018 Jan; 8(1):2. PubMed ID: 29329560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deep characterization of a common D4Z4 variant identifies biallelic DUX4 expression as a modifier for disease penetrance in FSHD2.
    Lemmers RJ; van der Vliet PJ; Balog J; Goeman JJ; Arindrarto W; Krom YD; Straasheijm KR; Debipersad RD; Özel G; Sowden J; Snider L; Mul K; Sacconi S; van Engelen B; Tapscott SJ; Tawil R; van der Maarel SM
    Eur J Hum Genet; 2018 Jan; 26(1):94-106. PubMed ID: 29162933
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.