These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 31067307)

  • 1. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
    Guerrero EN; Mitra J; Wang H; Rangaswamy S; Hegde PM; Basu P; Rao KS; Hegde ML
    Hum Mol Genet; 2019 Aug; 28(15):2459-2476. PubMed ID: 31067307
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
    Mitra J; Guerrero EN; Hegde PM; Liachko NF; Wang H; Vasquez V; Gao J; Pandey A; Taylor JP; Kraemer BC; Wu P; Boldogh I; Garruto RM; Mitra S; Rao KS; Hegde ML
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4696-4705. PubMed ID: 30770445
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SecinH3 Attenuates TDP-43 p.Q331K-Induced Neuronal Toxicity by Suppressing Endoplasmic Reticulum Stress and Enhancing Autophagic Flux.
    Hu W; Liu X; Wang S; Sun G; Zhao R; Lu H
    IUBMB Life; 2019 Feb; 71(2):192-199. PubMed ID: 30376609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis.
    Mitra J; Hegde ML
    J Exp Neurosci; 2019; 13():1179069519880166. PubMed ID: 31656396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phagocytosis of aggrecan-positive perineuronal nets surrounding motor neurons by reactive microglia expressing MMP-9 in TDP-43
    Cheung SW; Willis EF; Simmons DG; Bellingham MC; Noakes PG
    Neurobiol Dis; 2024 Oct; 200():106614. PubMed ID: 39067491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS.
    Dong H; Xu L; Wu L; Wang X; Duan W; Li H; Li C
    Neuroscience; 2014 Jul; 272():141-53. PubMed ID: 24785678
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
    Konopka A; Whelan DR; Jamali MS; Perri E; Shahheydari H; Toth RP; Parakh S; Robinson T; Cheong A; Mehta P; Vidal M; Ragagnin AMG; Khizhnyak I; Jagaraj CJ; Galper J; Grima N; Deva A; Shadfar S; Nicholson GA; Yang S; Cutts SM; Horejsi Z; Bell TDM; Walker AK; Blair IP; Atkin JD
    Mol Neurodegener; 2020 Sep; 15(1):51. PubMed ID: 32907630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complement components are upregulated and correlate with disease progression in the TDP-43
    Lee JD; Levin SC; Willis EF; Li R; Woodruff TM; Noakes PG
    J Neuroinflammation; 2018 Jun; 15(1):171. PubMed ID: 29859100
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage.
    Giannini M; Bayona-Feliu A; Sproviero D; Barroso SI; Cereda C; Aguilera A
    PLoS Genet; 2020 Dec; 16(12):e1009260. PubMed ID: 33301444
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.
    Ditsworth D; Maldonado M; McAlonis-Downes M; Sun S; Seelman A; Drenner K; Arnold E; Ling SC; Pizzo D; Ravits J; Cleveland DW; Da Cruz S
    Acta Neuropathol; 2017 Jun; 133(6):907-922. PubMed ID: 28357566
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution.
    De Marco G; Lomartire A; Calvo A; Risso A; De Luca E; Mostert M; Mandrioli J; Caponnetto C; Borghero G; Manera U; Canosa A; Moglia C; Restagno G; Fini N; Tarella C; Giordana MT; Rinaudo MT; Chiò A
    Neuropathol Appl Neurobiol; 2017 Feb; 43(2):133-153. PubMed ID: 27178390
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
    Guerrero EN; Mitra J; Wang H; Rangaswamy S; Hegde PM; Basu P; Rao KS; Hegde ML
    Hum Mol Genet; 2019 Sep; 28(18):3161-3162. PubMed ID: 31504503
    [No Abstract]   [Full Text] [Related]  

  • 14. DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.
    Penndorf D; Tadić V; Witte OW; Grosskreutz J; Kretz A
    PLoS One; 2017; 12(8):e0183684. PubMed ID: 28832631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Defects in synaptic transmission at the neuromuscular junction precede motor deficits in a TDP-43
    Chand KK; Lee KM; Lee JD; Qiu H; Willis EF; Lavidis NA; Hilliard MA; Noakes PG
    FASEB J; 2018 May; 32(5):2676-2689. PubMed ID: 29295857
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
    Arnold ES; Ling SC; Huelga SC; Lagier-Tourenne C; Polymenidou M; Ditsworth D; Kordasiewicz HB; McAlonis-Downes M; Platoshyn O; Parone PA; Da Cruz S; Clutario KM; Swing D; Tessarollo L; Marsala M; Shaw CE; Yeo GW; Cleveland DW
    Proc Natl Acad Sci U S A; 2013 Feb; 110(8):E736-45. PubMed ID: 23382207
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo.
    Kabashi E; Lin L; Tradewell ML; Dion PA; Bercier V; Bourgouin P; Rochefort D; Bel Hadj S; Durham HD; Vande Velde C; Rouleau GA; Drapeau P
    Hum Mol Genet; 2010 Feb; 19(4):671-83. PubMed ID: 19959528
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin.
    Liu S; Liu X; Kamdar RP; Wanotayan R; Sharma MK; Adachi N; Matsumoto Y
    Biochem Biophys Res Commun; 2013 Sep; 439(2):173-8. PubMed ID: 23994631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF.
    Jayaram S; Ketner G; Adachi N; Hanakahi LA
    Nucleic Acids Res; 2008 Oct; 36(18):5773-86. PubMed ID: 18782835
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.