These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 31067569)

  • 1. The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.
    Barta JA; Pauley K; Kossenkov AV; McMahon SB
    Carcinogenesis; 2020 Mar; 41(1):67-77. PubMed ID: 31067569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lung-Enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-Specific Gain of Oncogenic Function.
    Barta JA; McMahon SB
    Mol Cancer Res; 2019 Jan; 17(1):3-9. PubMed ID: 30224539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insights into Allosteric Mechanisms of the Lung-Enriched p53 Mutants V157F and R158L.
    Lei J; Li X; Cai M; Guo T; Lin D; Deng X; Li Y
    Int J Mol Sci; 2022 Sep; 23(17):. PubMed ID: 36077492
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.
    Yeudall WA; Vaughan CA; Miyazaki H; Ramamoorthy M; Choi MY; Chapman CG; Wang H; Black E; Bulysheva AA; Deb SP; Windle B; Deb S
    Carcinogenesis; 2012 Feb; 33(2):442-51. PubMed ID: 22114072
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plakoglobin restores tumor suppressor activity of p53
    Alaee M; Nool K; Pasdar M
    Cancer Sci; 2018 Jun; 109(6):1876-1888. PubMed ID: 29660231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.
    Vaughan CA; Singh S; Grossman SR; Windle B; Deb SP; Deb S
    Mol Oncol; 2017 Jun; 11(6):696-711. PubMed ID: 28423230
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.
    Wei S; Wang H; Lu C; Malmut S; Zhang J; Ren S; Yu G; Wang W; Tang DD; Yan C
    J Biol Chem; 2014 Mar; 289(13):8947-59. PubMed ID: 24554706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dominant-negative p53 mutant R248Q increases the motile and invasive activities of oral squamous cell carcinoma cells.
    Nakazawa S; Sakata KI; Liang S; Yoshikawa K; Iizasa H; Tada M; Hamada JI; Kashiwazaki H; Kitagawa Y; Yamazaki Y
    Biomed Res; 2019; 40(1):37-49. PubMed ID: 30787262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MicroRNA-324-5p-CUEDC2 Axis Mediates Gain-of-Function Mutant p53-Driven Cancer Stemness.
    Ghatak D; Datta A; Roychowdhury T; Chattopadhyay S; Roychoudhury S
    Mol Cancer Res; 2021 Oct; 19(10):1635-1650. PubMed ID: 34257080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.
    Kolukula VK; Sahu G; Wellstein A; Rodriguez OC; Preet A; Iacobazzi V; D'Orazi G; Albanese C; Palmieri F; Avantaggiati ML
    Oncotarget; 2014 Mar; 5(5):1212-25. PubMed ID: 24681808
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 gain-of-function mutations increase Cdc7-dependent replication initiation.
    Datta A; Ghatak D; Das S; Banerjee T; Paul A; Butti R; Gorain M; Ghuwalewala S; Roychowdhury A; Alam SK; Das P; Chatterjee R; Dasgupta M; Panda CK; Kundu GC; Roychoudhury S
    EMBO Rep; 2017 Nov; 18(11):2030-2050. PubMed ID: 28887320
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP.
    Saini H; Choudhary M; Sharma H; Chowdhury S; Mukherjee S; Chowdhury R
    Mol Biol Rep; 2023 Feb; 50(2):1045-1058. PubMed ID: 36385665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allele specific gain-of-function activity of p53 mutants in lung cancer cells.
    Vaughan CA; Frum R; Pearsall I; Singh S; Windle B; Yeudall A; Deb SP; Deb S
    Biochem Biophys Res Commun; 2012 Nov; 428(1):6-10. PubMed ID: 22989750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1.
    Tanaka N; Zhao M; Tang L; Patel AA; Xi Q; Van HT; Takahashi H; Osman AA; Zhang J; Wang J; Myers JN; Zhou G
    Oncogene; 2018 Mar; 37(10):1279-1292. PubMed ID: 29269868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma.
    Kang N; Wang Y; Guo S; Ou Y; Wang G; Chen J; Li D; Zhan Q
    BMC Cell Biol; 2018 Aug; 19(1):16. PubMed ID: 30126368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis.
    Singh S; Kumar M; Kumar S; Sen S; Upadhyay P; Bhattacharjee S; M N; Tomar VS; Roy S; Dutt A; Kundu TK
    J Biol Chem; 2019 Sep; 294(38):14081-14095. PubMed ID: 31366730
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway.
    Dong P; Xu Z; Jia N; Li D; Feng Y
    Mol Cancer; 2009 Nov; 8():103. PubMed ID: 19917135
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo.
    Xiong S; Chachad D; Zhang Y; Gencel-Augusto J; Sirito M; Pant V; Yang P; Sun C; Chau G; Qi Y; Su X; Whitley EM; El-Naggar AK; Lozano G
    Cancer Res; 2022 May; 82(10):1926-1936. PubMed ID: 35320355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance.
    Sankala H; Vaughan C; Wang J; Deb S; Graves PR
    Arch Biochem Biophys; 2011 Aug; 512(1):52-60. PubMed ID: 21621504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells.
    Di Fiore R; Marcatti M; Drago-Ferrante R; D'Anneo A; Giuliano M; Carlisi D; De Blasio A; Querques F; Pastore L; Tesoriere G; Vento R
    Bone; 2014 Mar; 60():198-212. PubMed ID: 24373920
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.