BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

707 related articles for article (PubMed ID: 31070059)

  • 1. The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy.
    Albadari N; Deng S; Li W
    Expert Opin Drug Discov; 2019 Jul; 14(7):667-682. PubMed ID: 31070059
    [No Abstract]   [Full Text] [Related]  

  • 2. Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways.
    Rohwer N; Cramer T
    Drug Resist Updat; 2011 Jun; 14(3):191-201. PubMed ID: 21466972
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer.
    Wigerup C; Påhlman S; Bexell D
    Pharmacol Ther; 2016 Aug; 164():152-69. PubMed ID: 27139518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.
    Burroughs SK; Kaluz S; Wang D; Wang K; Van Meir EG; Wang B
    Future Med Chem; 2013 Apr; 5(5):553-72. PubMed ID: 23573973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.
    Xia Y; Choi HK; Lee K
    Eur J Med Chem; 2012 Mar; 49():24-40. PubMed ID: 22305612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer.
    Ajith TA
    J Basic Clin Physiol Pharmacol; 2018 Dec; 30(1):11-18. PubMed ID: 30260792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions.
    Jones DT; Harris AL
    Expert Opin Ther Targets; 2012 May; 16(5):463-80. PubMed ID: 22512262
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting HIF-2α as therapy for advanced cancers.
    Murugesan T; Rajajeyabalachandran G; Kumar S; Nagaraju S; Jegatheesan SK
    Drug Discov Today; 2018 Jul; 23(7):1444-1451. PubMed ID: 29753878
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy.
    Yu T; Tang B; Sun X
    Yonsei Med J; 2017 May; 58(3):489-496. PubMed ID: 28332352
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor (HIF)-3alpha is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2.
    Pasanen A; Heikkilä M; Rautavuoma K; Hirsilä M; Kivirikko KI; Myllyharju J
    Int J Biochem Cell Biol; 2010 Jul; 42(7):1189-200. PubMed ID: 20416395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell-permeable hypoxia-inducible factor-1 (HIF-1) antagonists function as tumor radiosensitizers.
    Shi M; Guo XT; Shu MG; Chen FL; Li LW
    Med Hypotheses; 2007; 69(1):33-5. PubMed ID: 17280792
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
    Palayoor ST; Tofilon PJ; Coleman CN
    Clin Cancer Res; 2003 Aug; 9(8):3150-7. PubMed ID: 12912967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part II.
    Wilczynski J; Duechler M; Czyz M
    Arch Immunol Ther Exp (Warsz); 2011 Aug; 59(4):301-7. PubMed ID: 21625847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Comprehensive Description of Hypoxia-inducible Factor 2α Inhibitors as Anticancer Agents: A Mini-review.
    Lu H; Zhu Y; Liu W; Yan Y; Jiang X; Wang Q; Zhao Y; He M; Wei M
    Curr Med Chem; 2023; 30(25):2835-2849. PubMed ID: 36043744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer.
    Jarman EJ; Ward C; Turnbull AK; Martinez-Perez C; Meehan J; Xintaropoulou C; Sims AH; Langdon SP
    Breast Cancer Res; 2019 Jan; 21(1):10. PubMed ID: 30670058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia.
    Aquino-Gálvez A; González-Ávila G; Delgado-Tello J; Castillejos-López M; Mendoza-Milla C; Zúñiga J; Checa M; Maldonado-Martínez HA; Trinidad-López A; Cisneros J; Torres-Espíndola LM; Hernández-Jiménez C; Sommer B; Cabello-Gutiérrez C; Gutiérrez-González LH
    Oncol Rep; 2016 Jan; 35(1):577-83. PubMed ID: 26548300
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia-inducible factors and sphingosine 1-phosphate signaling.
    Cuvillier O; Ader I
    Anticancer Agents Med Chem; 2011 Nov; 11(9):854-62. PubMed ID: 21707486
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors.
    Zhao J; Du F; Luo Y; Shen G; Zheng F; Xu B
    Cancer Treat Rev; 2015 Jul; 41(7):623-33. PubMed ID: 25981453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells.
    Zhao D; Zhai B; He C; Tan G; Jiang X; Pan S; Dong X; Wei Z; Ma L; Qiao H; Jiang H; Sun X
    Cell Signal; 2014 May; 26(5):1030-9. PubMed ID: 24486412
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The inhibitory effect of hypoxic cytotoxin on the expansion of cancer stem cells in ovarian cancer.
    Nozawa-Suzuki N; Nagasawa H; Ohnishi K; Morishige K
    Biochem Biophys Res Commun; 2015 Feb; 457(4):706-11. PubMed ID: 25619133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.