BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 31070897)

  • 1. pH-Induced Misfolding Mechanism of Prion Protein: Insights from Microsecond-Accelerated Molecular Dynamics Simulations.
    Zhou S; Shi D; Liu X; Yao X; Da LT; Liu H
    ACS Chem Neurosci; 2019 Jun; 10(6):2718-2729. PubMed ID: 31070897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disassociation of β1-α1-β2 from the α2-α3 domain of prion protein (PrP) is a prerequisite for the conformational conversion of PrP
    Chandrasekaran P; Santosh Kumar C; Rangachari K; Sekar K
    Int J Biol Macromol; 2019 Sep; 136():368-376. PubMed ID: 31207327
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation-Dependent Refolding of Prion Protein Unveils Amyloidogenic-Related Structural Ramifications: Insights from Molecular Dynamics Simulations.
    Palaniappan C; Narayanan RC; Sekar K
    ACS Chem Neurosci; 2021 Aug; 12(15):2810-2819. PubMed ID: 34296847
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preventing misfolding of the prion protein by trimethylamine N-oxide.
    Bennion BJ; DeMarco ML; Daggett V
    Biochemistry; 2004 Oct; 43(41):12955-63. PubMed ID: 15476389
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of pH and aggregation in the human prion conversion into scrapie form: a study using molecular dynamics with excited normal modes.
    Lima AN; de Oliveira RJ; Braz ASK; de Souza Costa MG; Perahia D; Scott LPB
    Eur Biophys J; 2018 Jul; 47(5):583-590. PubMed ID: 29546436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Detailed computational analysis revealed mutation V210I on PrP induced conformational conversion on β2-α2 loop and α2-α3.
    Chandrasekaran P; Rajasekaran R
    Mol Biosyst; 2016 Oct; 12(10):3223-33. PubMed ID: 27523988
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rare large scale subdomain motions in prion protein can initiate aggregation.
    Schwarzinger S; Horn AH; Ziegler J; Sticht H
    J Biomol Struct Dyn; 2006 Jun; 23(6):581-90. PubMed ID: 16615804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Dynamics Simulation Study on the Binding and Stabilization Mechanism of Antiprion Compounds to the "Hot Spot" Region of PrP
    Zhou S; Liu X; An X; Yao X; Liu H
    ACS Chem Neurosci; 2017 Nov; 8(11):2446-2456. PubMed ID: 28795797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The folding mechanism and key metastable state identification of the PrP127-147 monomer studied by molecular dynamics simulations and Markov state model analysis.
    Zhou S; Wang Q; Wang Y; Yao X; Han W; Liu H
    Phys Chem Chem Phys; 2017 May; 19(18):11249-11259. PubMed ID: 28406520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular dynamics simulations capture the misfolding of the bovine prion protein at acidic pH.
    Cheng CJ; Daggett V
    Biomolecules; 2014 Feb; 4(1):181-201. PubMed ID: 24970211
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pH-triggered conversion of the PrP(c) to PrP(sc.).
    Zhou GP; Huang RB
    Curr Top Med Chem; 2013; 13(10):1152-63. PubMed ID: 23647538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unraveling the Molecular Mechanism of Prion H2 C-Terminus Misfolding by Metadynamics Simulations.
    Xu Z; Liu H; Wang S; Zhang Q; Yao X; Zhou S; Liu H
    ACS Chem Neurosci; 2020 Mar; 11(5):772-782. PubMed ID: 32023408
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and dynamic properties of the human prion protein.
    Chen W; van der Kamp MW; Daggett V
    Biophys J; 2014 Mar; 106(5):1152-63. PubMed ID: 24606939
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular Mechanism of the Misfolding and Oligomerization of the Prion Protein: Current Understanding and Its Implications.
    Singh J; Udgaonkar JB
    Biochemistry; 2015 Jul; 54(29):4431-42. PubMed ID: 26171558
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Temperature-Induced Misfolding in Prion Protein: Evidence of Multiple Partially Disordered States Stabilized by Non-Native Hydrogen Bonds.
    Chamachi NG; Chakrabarty S
    Biochemistry; 2017 Feb; 56(6):833-844. PubMed ID: 28102071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The octarepeat region of the prion protein is conformationally altered in PrP(Sc).
    Yam AY; Gao CM; Wang X; Wu P; Peretz D
    PLoS One; 2010 Feb; 5(2):e9316. PubMed ID: 20195363
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversibility of prion misfolding: insights from constant-pH molecular dynamics simulations.
    Vila-Viçosa D; Campos SR; Baptista AM; Machuqueiro M
    J Phys Chem B; 2012 Aug; 116(30):8812-21. PubMed ID: 22803931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mapping the early steps in the pH-induced conformational conversion of the prion protein.
    Alonso DO; DeArmond SJ; Cohen FE; Daggett V
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):2985-9. PubMed ID: 11248018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prion protein aggregation and fibrillogenesis in vitro.
    Stöhr J
    Subcell Biochem; 2012; 65():91-108. PubMed ID: 23225001
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prion protein-Semisynthetic prion protein (PrP) variants with posttranslational modifications.
    Hackl S; Becker CFW
    J Pept Sci; 2019 Oct; 25(10):e3216. PubMed ID: 31713950
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.