86 related articles for article (PubMed ID: 31070916)
1. Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.
Leung L; Niculescu-Duvaz D; Smithen D; Lopes F; Callens C; McLeary R; Saturno G; Davies L; Aljarah M; Brown M; Johnson L; Zambon A; Chambers T; Ménard D; Bayliss N; Knight R; Fish L; Lawrence R; Challinor M; Tang H; Marais R; Springer C
J Med Chem; 2019 Jun; 62(12):5863-5884. PubMed ID: 31070916
[TBL] [Abstract][Full Text] [Related]
2. Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy.
Faridoon ; Zheng J; Zhang T; Tong S; Liu T; Cui J; Xu H; Hu D; Shen Y; Yin Y; Zhao D; Tan C; Dong X; Chen J; Ji F; Tong C; Li JJ; Li J; Zhang G
J Med Chem; 2024 Jun; 67(11):9431-9446. PubMed ID: 38818879
[TBL] [Abstract][Full Text] [Related]
3. A molecular model of human Lysyl Oxidase (LOX) with optimal copper orientation in the catalytic cavity for induced fit docking studies with potential modulators.
Bhuvanasundar R; John A; Sulochana KN; Coral K; Deepa PR; Umashankar V
Bioinformation; 2014; 10(7):406-12. PubMed ID: 25187679
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and biological studies of nitric oxide-donating piperlongumine derivatives triggered by lysyl oxidase as anti-triple negative breast cancer agents.
Zou Y; Wan X; Ding Z; Tang C; Wang C; Chen X
Fitoterapia; 2024 Jun; 177():106091. PubMed ID: 38908760
[TBL] [Abstract][Full Text] [Related]
5. 2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
Smithen DA; Leung LMH; Challinor M; Lawrence R; Tang H; Niculescu-Duvaz D; Pearce SP; Mcleary R; Lopes F; Aljarah M; Brown M; Johnson L; Thomson G; Marais R; Springer C
J Med Chem; 2020 Mar; 63(5):2308-2324. PubMed ID: 31430136
[TBL] [Abstract][Full Text] [Related]
6. Lysyl oxidases: from enzyme activity to extracellular matrix cross-links.
Vallet SD; Ricard-Blum S
Essays Biochem; 2019 Sep; 63(3):349-364. PubMed ID: 31488698
[TBL] [Abstract][Full Text] [Related]
7. Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis.
Nguyen XX; Nishimoto T; Takihara T; Mlakar L; Bradshaw AD; Feghali-Bostwick C
Am J Physiol Lung Cell Mol Physiol; 2021 Jan; 320(1):L29-L40. PubMed ID: 33026236
[TBL] [Abstract][Full Text] [Related]
8. Novel
Van Gucht I; Krebsova A; Diness BR; Laga S; Adlam D; Kempers M; Samani NJ; Webb TR; Baranowska AA; Van Den Heuvel L; Perik M; Luyckx I; Peeters N; Votypka P; Macek M; Meester J; Van Laer L; Verstraeten A; Loeys BL
Int J Mol Sci; 2021 Jul; 22(13):. PubMed ID: 34281165
[TBL] [Abstract][Full Text] [Related]
9. A restriction fragment length polymorphism results in a nonconservative amino acid substitution encoded within the first exon of the human lysyl oxidase gene.
Csiszar K; Mariani TJ; Gosin JS; Deak SB; Boyd CD
Genomics; 1993 May; 16(2):401-6. PubMed ID: 8100215
[TBL] [Abstract][Full Text] [Related]
10. Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy.
Borst R; Meyaard L; Pascoal Ramos MI
J Transl Med; 2024 Apr; 22(1):382. PubMed ID: 38659022
[TBL] [Abstract][Full Text] [Related]
11. Copper homeostasis and cuproptosis in tumor pathogenesis and therapeutic strategies.
Bian C; Zheng Z; Su J; Chang S; Yu H; Bao J; Xin Y; Jiang X
Front Pharmacol; 2023; 14():1271613. PubMed ID: 37767404
[TBL] [Abstract][Full Text] [Related]
12. Stromal inflammation, fibrosis and cancer: An old intuition with promising potential.
Oey O; Sunjaya AF; Khan Y; Redfern A
World J Clin Oncol; 2023 Jul; 14(7):230-246. PubMed ID: 37583950
[TBL] [Abstract][Full Text] [Related]
13. Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics.
Zhang J; Hu Z; Horta CA; Yang J
Semin Cancer Biol; 2023 Jan; 88():46-66. PubMed ID: 36521737
[TBL] [Abstract][Full Text] [Related]
14. A 3D-Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase-Like 2.
Meier AA; Kuczera K; Mure M
Int J Mol Sci; 2022 Nov; 23(21):. PubMed ID: 36362176
[TBL] [Abstract][Full Text] [Related]
15. Lysyl Oxidase Family Proteins: Prospective Therapeutic Targets in Cancer.
Wang W; Wang X; Yao F; Huang C
Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293126
[TBL] [Abstract][Full Text] [Related]
16. Collagen Remodeling along Cancer Progression Providing a Novel Opportunity for Cancer Diagnosis and Treatment.
Song K; Yu Z; Zu X; Li G; Hu Z; Xue Y
Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142424
[TBL] [Abstract][Full Text] [Related]
17. Copper in the tumor microenvironment and tumor metastasis.
Kamiya T
J Clin Biochem Nutr; 2022 Jul; 71(1):22-28. PubMed ID: 35903604
[TBL] [Abstract][Full Text] [Related]
18. Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy.
Jiang Y; Zhang H; Wang J; Liu Y; Luo T; Hua H
J Hematol Oncol; 2022 Mar; 15(1):34. PubMed ID: 35331296
[TBL] [Abstract][Full Text] [Related]
19. Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2.
Meier AA; Moon HJ; Toth R; Folta-Stogniew E; Kuczera K; Middaugh CR; Mure M
Biomolecules; 2021 Dec; 11(12):. PubMed ID: 34944490
[TBL] [Abstract][Full Text] [Related]
20. Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype.
Bahcecioglu G; Yue X; Howe E; Guldner I; Stack MS; Nakshatri H; Zhang S; Zorlutuna P
Adv Sci (Weinh); 2021 Nov; 8(22):e2100128. PubMed ID: 34617419
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
